To compare the efficacy and safety of tamsulosin and terazosin in the treatment of upper urinary stones after lithotripsy with lithotripsy, and to provide evidence for clinical safety and rational drug use.

A retrospective analysis was made on 77 patients with lower ureteral stone streets after upper urinary stones were treated with extracorporeal lithotripsy in our hospital from January 2017 to December 2017. According to the type of castor 1 receptor blockers used, there were 42 cases in the tensoroxine group and 35 cases in the trazozine group. The curative effect and the occurrence of cardiovascular adverse reactions were compared between the groups.

The stone removal rate of the tamsulosin group was 80.95%, which was significantly higher than that of the trazozine group (60.00%)(P<0.05). The average frequency of renal colic attack in the tamsulosin group was 0.50 times, which was significantly lower than that in the terazosin group was 2.11 times(P<0.05). The average longest duration of renal colic in the tamsulosin group was 0.71 hours, significantly lower than that in the trazosin group(P<0.05). The incidence of postural hypotension was 9.52%, palpitation 11.90% and syncope 0.0% in the tamsulosin group, all significantly lower than 31.43%, 34.29% and 11.43% in the trazozine group(P<0.05).

The effect of tamsulosin on conservative lithotripsy in ureteral calculi after extracorporeal shockwave lithotripsy is su-perior to that of terazosin.

Urinary Calculi; Adrenergic alpha-1 Receptor Antagonists; Lithotripsy