To explore the values of small dense low-density lipoprotein (sdLDL), apolipoprotein A1 (apoA1), apolipoprotein B (apoB), and lipoprotein a (LPa) levels in evaluating the severity of clinical classification in patients with coronary heart diseases (CHD).

A total of 72 patients with CHD (CHD group) and 35 healthy people (healthy group) in our hospital from January to June 2020 were selected. There were 44 males and 28 females in the CHD group, with the age of (67.01±6.42) years old; there were 23 males and 12 females in the healthy group, with the age of (65.43±5.27) years old. Seventy-two patients with coronary heart diseases were divided into 3 groups according to the clinical classification, including 26 patients with stable angina pectoris, 25 patients with unstable angina pectoris, and 21 patients with acute myocardial infarction. The levels of sdLDL, apoA1, apoB, and LPa were detected, and the data of all groups were analyzed and discussed.

The levels of sdLDL, apoB, and LPa in the CHD group were (1.53±0.32) mmol/L, (1.17±0.27) g/L, (237.16±40.29) g/L, which were higher than those in the healthy group [(0.92±0.19) mmol/L, (0.78±0.22) g/L, (117.06±28.20) g/L], the level of apoA1 in the CHD group was lower than that in the healthy group [(0.99±0.23) g/L vs.(1.24±0.35) g/L],with statistically significant differences (allP<0.05). In the CHD group, sdLDL, apoB, and LPa increased with the severity of clinical classification, while apoA1 decreased with the severity of clinical classification (allP<0.05).

The levels of sdLDL, apoA1, apoB, and LPa in patients with CHD are correlated with the severity of clinical classification, which have high evaluation values.

Coronary heart disease; Clinical classification; Small dense low-density lipoprotein; Apolipoprotein A1; Apolipoprotein B; Lipoprotein a