Expert Opinion
Role of hepatic venous pressure gradient in the overall management process of portal hypertension
Wang Hongliang, Sun Junhui
Published 2020-09-20
Cite as Chin J Hepatol, 2020, 28(9): 728-731. DOI: 10.3760/cma.j.cn501113-20200613-00313
Abstract
Portal hypertension is a common complication of many chronic liver diseases and an important factor affecting the clinical prognosis of patients. Portal hypertension can bring a series of serious complications such as esophagogastric varices, gastrointestinal bleeding, ascites, spontaneous peritonitis, renal insufficiency, hypersplenism, and hepatopulmonary syndrome. Hepatic venous pressure gradient is the best clinical indicator that indirectly reflects the portal venous pressure. Currently, it is the gold standard test for diagnosing clinically significant portal hypertension. In addition, the hepatic venous pressure gradient has important application value in predicting the degree of liver cirrhosis, the risk and prognosis of portal hypertension variceal bleeding, ascites production, portal hypertension drugs reduction, and antiviral drugs efficacy. At the same time, individualized treatment based on portal pressure gradient has important theoretical and clinical significance, and provides new clinical ideas in the overall management of patients with portal hypertension.
Key words:
Portal hypertension; Hepatic venous pressure gradient; Whole course of management
Contributor Information
Wang Hongliang
Hepatobiliary and Pancreatic Interventional Treatment Center, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases
Zhejiang Provincial Research Center for Diagnosis and Treatment of Heapatobiliary Diseases
Hangzhou 310003, China
Sun Junhui
Hepatobiliary and Pancreatic Interventional Treatment Center, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases
Zhejiang Provincial Research Center for Diagnosis and Treatment of Heapatobiliary Diseases
Hangzhou 310003, China