Wang Yu, Wang Min, Zhang Guanhua, He Fuliang, Ou Xiaojuan, Wang Xiaoming, Jia Jidong
Abstract
The liver is abundant in blood supply and receives 25% of the cardiac output via the hepatic artery and portal vein. Circulatory disorders may cause hepatic injury, resulting in congestive hepatopathy(CH) and ischemic hepatitis(IH). Hepatic congestion arising from increased hepatic venous pressure and decreased cardiac output is the common pathophysiological basis of both CH and IH. In addition, extensive arteriovenous shunts affect portal pressure and cardiac function, leading to alterations of hepatic blood supply. The current review summarizes the pathophysiology, clinical manifestations and therapeutic interventions of the above diseases, in order to provide reference for clinical practice.
Key words:
Circulation system; Cardiovascular disease; Liver disease; Liver injury
Contributor Information
Wang Yu
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Wang Min
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Zhang Guanhua
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
He Fuliang
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Ou Xiaojuan
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Wang Xiaoming
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Jia Jidong
Liver Research Center, Beijing Friendship Hospital, Capital Medical University
Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis &
National Clinical Research Center for Digestive Diseases, Beijing 100050, China
