Review
Research advances on biomaterials for the delivery of growth factors to regulate wound repair
Weng Tingting, Cai Chenghao, Han Chunmao, Wang Xingang
Published 2022-07-20
Cite as Chin J Burns, 2022, 38(7): 691-696. DOI: 10.3760/cma.j.cn501225-20220430-00166
Abstract
Wound repair is a highly coordinated and mutually regulated complex process involving various kinds of cells, extracellular matrices and cytokines. A variety of growth factors play an important regulatory role in wound healing, and it is critical to achieve effective delivery and sustained function of growth factors. In recent years, the application of biomaterials in tissue engineering has shown great potential, and the effective delivery of growth factors by biomaterials has attracted increasing attention. Based on this, this paper introduces the mechanism of related growth factors in the process of wound healing, focusing on the recent progress of biomaterial delivery of growth factors to accelerate wound healing, in order to provide new enlightenment for clinical wound treatment.
Key words:
Wound healing; Biocompatible materials; Tissue engineering; Skin; growth factors
Contributor Information
Weng Tingting
The Second Clinical College, College of Medicine, Zhejiang University, Hangzhou 310009, China
Cai Chenghao
The Second Clinical College, College of Medicine, Zhejiang University, Hangzhou 310009, China
Han Chunmao
Department of Burn and Wound Repair, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
Wang Xingang
Department of Burn and Wound Repair, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
