综述
ENGLISH ABSTRACT
吸入装置:慢性阻塞性肺疾病管理中不容忽视的环节
刘锦铭
作者及单位信息
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DOI: 10.3760/cma.j.issn.1001-0939.2019.02.009
The importance of inhalation therapy in COPD management
Liu Jinming
Authors Info & Affiliations
Liu Jinming
·
DOI: 10.3760/cma.j.issn.1001-0939.2019.02.009
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摘要

慢性阻塞性肺病(慢阻肺)已成为我国第三大致死性疾病。吸入治疗是慢阻肺治疗的主要给药方式,但其是否能成功实施依赖于患者对吸入装置的正确使用,而这仍是慢阻肺疾病管理中的一个巨大挑战。本文将从吸入装置、患者和医疗工作者等三个方面,对如何实现成功的吸入治疗进行探讨。

引用本文

刘锦铭. 吸入装置:慢性阻塞性肺疾病管理中不容忽视的环节[J]. 中华结核和呼吸杂志,2019,42(2):122-124.

DOI:10.3760/cma.j.issn.1001-0939.2019.02.009

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最新的流行病学调查结果显示,我国20岁以上人群的慢性阻塞性肺疾病(慢阻肺)的患病率为8.6%,患病人数接近1亿 [ 1 ],而其中40岁以上人群的患病率高达13.6%,以此推算有将近7千多万的慢阻肺患者 [ 2 ]。目前,慢阻肺已成为我国第三大致死性疾病,仅次于脑卒中和缺血性心脏病 [ 3 ]。吸入治疗可直接作用于靶器官,具有起效迅速和药物全身暴露量少的特点,一直是慢阻肺治疗的主要给药方式,而其是否能成功实施依赖于患者对吸入装置的正确使用,目前看来这依然是慢阻肺疾病管理中的一个挑战 [ 4 , 5 ]。本文将从吸入装置、患者和医疗工作者等三个方面,对如何实现成功的吸入治疗进行探讨。
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参考文献
[1]
Wang C , Xu J , Yang L ,et al. China Pulmonary Health Study Group. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study):a national cross-sectional study[J]. Lancet, 2018,391(10131):1706-1717. DOI: 0.1016/S0140-6736(18)30841-9 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Fang L , Gao P , Bao H ,et al. Chronic obstructive pulmonary disease in China:a nationwide prevalence study[J]. Lancet Respir Med, 2018,6(6):421-430. DOI: 10.1016/S2213-2600(18)30103-6 .
返回引文位置Google Scholar
百度学术
万方数据
[3]
Yang G , Wang Y , Zeng Y ,et al. Rapid health transition in China, 1990—2010:findings from the Global Burden of Disease Study 2010[J]. Lancet, 2013,381(9882):1987-2015. DOI: 10.1016/S0140-6736(13)61097-1 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
Global Initiative for Chronic Obstructive Lung Disease(GOLD). Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease: 2019 Report.[EB/OL].[ 2018-05-12]. https://goldcopd.org/wp-content/uploads/2018/11/GOLD-2019-v1.6-FINAL-08Nov2018-wms.pdf.
返回引文位置Google Scholar
百度学术
万方数据
[5]
中华医学会呼吸病学分会慢性阻塞性肺疾病学组. 慢性阻塞性肺疾病诊治指南(2013年修订版)[J]. 中华结核和呼吸杂志 201336(4):1-10DOI: 10.3760/cma.j.issn.1001-0939.2013.04.000 .
返回引文位置Google Scholar
百度学术
万方数据
[6]
Fink JB , Colice GL , Hodder R . Inhaler devices for patients with COPD[J]. COPD, 2013,10(4):523-535. DOI: 10.3109/15412555.2012.761960 .
返回引文位置Google Scholar
百度学术
万方数据
[7]
Capstick TG , Clifton IJ . Inhaler technique and training in people with chronic obstructive pulmonary disease and asthma[J]. Expert Rev Respir Med, 2012,6(1):91-101. DOI: 10.1586/ers.11.89 .
返回引文位置Google Scholar
百度学术
万方数据
[8]
Newman SP . Aerosol deposition considerations in inhalation therapy[J]. Chest, 1985,88(2Suppl):152S-160S.
返回引文位置Google Scholar
百度学术
万方数据
[9]
Palander A , Mattila T , Karhu M ,et al. In vitro comparison of three salbutamol-containing multidose dry powder inhalers[J]. Clin Drug Investig, 2000,20(1):25-33. DOI: 10.2165/00044011-200020010-00004 .
返回引文位置Google Scholar
百度学术
万方数据
[10]
Chodosh S , Flanders JS , Kesten S ,et al. Effective delivery of particles with the HandiHaler dry powder inhalation system over a range of chronic obstructive pulmonary disease severity[J]. J Aerosol Med, 2001,14(3):309-315. DOI: 10.1089/089426801316970268 .
返回引文位置Google Scholar
百度学术
万方数据
[11]
Bourbeau J , Bartlett SJ . Patient adherence in COPD[J]. Thorax, 2008,63(9):831-838. DOI: 10.1136/thx.2007.086041 .
返回引文位置Google Scholar
百度学术
万方数据
[12]
Lewis A , Torvinen S , Dekhuijzen PN ,et al. The economic burden of asthma and chronic obstructive pulmonary disease and the impact of poor inhalation technique with commonly prescribed dry powder inhalers in three European countries[J]. BMC Health Serv Res, 2016,16:251. DOI: 10.1186/s12913-016-1482-7 .
返回引文位置Google Scholar
百度学术
万方数据
[13]
Chrystyn H , van der Palen J , Sharma R ,et al. Device errors in asthma and COPD:systematic literature review and meta-analysis[J]. NPJ Prim Care Respir Med, 2017,27(1):22. DOI: 10.1038/s41533-017-0016-z .
返回引文位置Google Scholar
百度学术
万方数据
[14]
Rogueda P , Traini D . The future of inhalers:how can we improve drug delivery in asthma and COPD?[J]. Expert Rev Respir Med, 2016,10(10):1041-1044. DOI: 10.1080/17476348.2016.1227246 .
返回引文位置Google Scholar
百度学术
万方数据
[15]
Usmani OS , Lavorini F , Marshall J ,et al. Critical inhaler errors in asthma and COPD:a systematic review of impact on health outcomes[J]. Respir Res, 2018,19(1):10. DOI: 10.1186/s12931-017-0710-y .
返回引文位置Google Scholar
百度学术
万方数据
[16]
Dekhuijzen PN , Vincken W , Virchow JC ,et al. Prescription of inhalers in asthma and COPD:towards a rational, rapid and effective approach[J]. Respir Med, 2013,107(12):1817-1821. DOI: 10.1016/j.rmed.2013.09.013 .
返回引文位置Google Scholar
百度学术
万方数据
[17]
Chrystyn H , Small M , Milligan G ,et al. Impact of patients′ satisfaction with their inhalers on treatment compliance and health status in COPD[J]. Respir Med, 2014,108(2):358-365. DOI: 10.1016/j.rmed.2013.09.021 .
返回引文位置Google Scholar
百度学术
万方数据
[18]
Vogelmeier CF , Criner GJ , Martinez FJ ,et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary[J]. Eur Respir J, 2017,49(3). 10.1183/3993003.00214-2017 . DOI:.
返回引文位置Google Scholar
百度学术
万方数据
[19]
熊焕文吴地尧宋宁燕. 哮喘、COPD患者吸入治疗现状及影响吸入技术因素调查[J]. 南昌大学学报(医学版) 201050(2):112-114DOI: 10.3969/j.issn.1000-2294.2010.02.040 .
返回引文位置Google Scholar
百度学术
万方数据
[20]
Partridge MR , Dal Negro RW , Olivieri D . Understanding patients with asthma and COPD:insights from a European study[J]. Prim Care Respir J, 2011,20(3):315-323. DOI: 10.4104/pcrj.2011.00056 .
返回引文位置Google Scholar
百度学术
万方数据
[21]
van der Palen J , Thomas M , Chrystyn H ,et al. A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma:comparison of ELLIPTA with other inhaler devices[J]. NPJ Prim Care Respir Med, 2017,27:17001. DOI: 10.1038/npjpcrm.2017.1 .
返回引文位置Google Scholar
百度学术
万方数据
[22]
Plaza V , Sanchis J , Roura P ,et al. Physicians′ knowledge of inhaler devices and inhalation techniques remains poor in Spain[J]. J Aerosol Med Pulm Drug Deliv, 2012,25(1):16-22. DOI: 10.1089/jamp.2011.0895 .
返回引文位置Google Scholar
百度学术
万方数据
[23]
Plaza V , Giner J , Rodrigo GJ ,et al. Errors in the use of inhalers by health care professionals:a systematic review[J]. J Allergy Clin Immunol Pract, 2018,6:987-995. DOI: 10.1016/j.jaip.2017.12.032 .
返回引文位置Google Scholar
百度学术
万方数据
[24]
Hochrainer D , Hölz H , Kreher C ,et al. Comparison of the aerosol velocity and spray duration of Respimat Soft Mist inhaler and pressurized metered dose inhalers[J]. J Aerosol Med, 2005,18(3):273-282. DOI: 10.1089/jam.2005.18.273 .
返回引文位置Google Scholar
百度学术
万方数据
[25]
Dalby RN , Eicher J , Zierenberg B . Development of Respimat R Soft Mist TM Inhaler and its clinical utility in respiratory disorders [J]. Med Devices(Auckl), 2011,4:145-155. DOI: 10.2147/MDER.S7409 .
返回引文位置Google Scholar
百度学术
万方数据
[26]
Pitcairn G , Reader S , Pavia D ,et al. Deposition of corticosteroid aerosol in the human lung by Respimat Soft Mist inhaler compared to deposition by metered dose inhaler or by Turbuhaler dry powder inhaler[J]. J Aerosol Med, 2005,18(3):264-272. DOI: 10.1089/jam.2005.18.264 .
返回引文位置Google Scholar
百度学术
万方数据
[27]
Newman SP . Use of gamma scintigraphy to evaluate the performance of new inhalers[J]. J Aerosol Med, 1999,12(Suppl 1):S25-31.
返回引文位置Google Scholar
百度学术
万方数据
[28]
Restrepo RD , Alvarez MT , Wittnebel LD ,et al. Medication adherence issues in patients treated for COPD[J]. Int J Chron Obstruct Pulmon Dis, 2008,3(3):371-384. DOI: 10.2147/COPD.S3036 .
返回引文位置Google Scholar
百度学术
万方数据
[29]
Leach CL , Davidson PJ , Boudreau RJ . Improved airway targeting with the CFC-free HFA-beclomethasone metered-dose inhaler compared with CFC-beclomethasone[J]. Eur Respir J, 1998,12(6):1346-1353.
返回引文位置Google Scholar
百度学术
万方数据
[30]
Haidl P , Heindl S , Siemon K ,et al. Inhalation device requirements for patients′ inhalation maneuvers[J]. Respir Med, 2016,118:65-75. DOI: 10.1016/j.rmed.2016.07.013 .
返回引文位置Google Scholar
百度学术
万方数据
[31]
Ghosh S , Ohar JA , Drummond MB . Peak inspiratory flow rate in chronic obstructive pulmonary disease: implications for dry powder inhalers[J]. J Aerosol Med Pulm Drug Deliv, 2017,30(6):381-387. DOI: 10.1089/jamp.2017.1416 .
返回引文位置Google Scholar
百度学术
万方数据
[32]
Hira D , Koide H , Nakamura S ,et al. Assessment of inhalation flow patterns of soft mist inhaler co-prescribed with dry powder inhaler using inspiratory flow meter for multi inhalation devices[J]. PLoS One, 2018,13(2):e0193082. DOI: 10.1371/journal.pone.0193082 .
返回引文位置Google Scholar
百度学术
万方数据
[33]
Hill LS , Slater AL . A comparison of the performance of two modern multidose dry powder asthma inhalers[J]. Respir Med, 1998,92(1):105-110.
返回引文位置Google Scholar
百度学术
万方数据
[34]
National Clinical Guideline Centre(UK). Chronic obstructive pulmonary disease:management of chronic obstructive pulmonary disease in adults in primary and secondary care[M]. London:National Clinical Guideline Centre, 2010.
[35]
Rogliani P , Calzetta L , Coppola A ,et al. Optimizing drug delivery in COPD:the role of inhaler devices[J]. Respir Med, 2017,124:6-14. DOI: 10.1016/j.rmed.2017.01.006 .
返回引文位置Google Scholar
百度学术
万方数据
备注信息
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刘锦铭,Email: mocdef.3ab617002uilgnimnij
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所有作者均声明不存在利益冲突
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