支气管哮喘-慢性阻塞性肺疾病重叠精准诊断之探索

戴元荣; 葛翔挺

doi:10.3760/cma.j.issn.1001-0939.2019.03.006

高级检索

IP登录

登录IP

切换

退出

中华结核和呼吸杂志

• 专题笔谈 •

ENGLISH ABSTRACT

支气管哮喘-慢性阻塞性肺疾病重叠精准诊断之探索

作者及单位信息

出版日期： 2019 -03 -12 ·

DOI： 10.3760/cma.j.issn.1001-0939.2019.03.006

The diagnostic issues of asthma and chronic obstructive pulmonary clisease

Authors Info & Affiliations

Dai Yuanrong

Ge Xiangting

Published： 2019 -03 -12 ·

DOI： 10.3760/cma.j.issn.1001-0939.2019.03.006

841

176

APP内阅读

摘要

支气管哮喘-慢性阻塞性肺疾病重叠（ACO）为近年研究热点，其机制不明，诊治的循证学依据不足，故各国指南或共识对ACO的诊断标准不一。本文简述ACO演变，比较各指南或共识诊断标准异同，评价并寻求有助于诊断的生物标志物，探讨不同分型及意义，提出目前诊疗思路和建议。

引用本文

戴元荣,葛翔挺. 支气管哮喘-慢性阻塞性肺疾病重叠精准诊断之探索[J]. 中华结核和呼吸杂志,2019,42(3)：176-178.

DOI:10.3760/cma.j.issn.1001-0939.2019.03.006

PERMISSIONS

Request permissions for this article from CCC.

评价本文

*以上评分为匿名评价

版权归中华医学会所有。

未经授权，不得转载、摘编本刊文章，不得使用本刊的版式设计。

除非特别声明，本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

在临床实践中，支气管哮喘（哮喘）和慢性阻塞性肺疾病（慢阻肺）有时很难区分，特别是在老年患者、吸烟者和既往吸烟者中，有时两者出现重叠，即哮喘-慢阻肺重叠（ACO），这时患者症状更严重，急性加重和住院风险更高，预后更差，需要额外的治疗。阐明ACO发病机制、明确诊断方法及治疗策略，具有重要意义。

试读结束，您可以通过登录机构账户或个人账户后获取全文阅读权限。

已是订阅账户? 登录

摘要
参考文献

参考文献

[1]

Leung JM , Sin DD . Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets[J]. BMJ, 2017,358:j3772. DOI: 10.1136/bmj.j3772 .

返回引文位置Google Scholar

百度学术

万方数据

[2]

Miravitlles M , Soler-Cataluña JJ , Calle M ,et al. Spanish Guidelines for Management of Chronic Obstructive Pulmonary Disease (GesEPOC) 2017. Pharmacological Treatment of Stable Phase[J]. Arch Bronconeumol, 2017,53(6):324-335. DOI: 10.1016/j.arbres.2017.03.018 .

返回引文位置Google Scholar

百度学术

万方数据

[3]

Tommola M , Ilmarinen P , Tuomisto LE ,et al. Differences between asthma-COPD overlap syndrome and adult-onset asthma[J]. Eur Respir J, 2017,49(5). DOI: 10.1183/13993003.02383-2016 .

返回引文位置Google Scholar

百度学术

万方数据

[4]

James AJ , Reinius LE , Verhoek M ,et al. Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease[J]. Am J Respir Crit Care Med, 2016,193(2):131-142. DOI: 10.1164/rccm.201504-0760OC .

返回引文位置Google Scholar

百度学术

万方数据

[5]

Chen FJ , Huang XY , Liu YL ,et al. Importance of fractional exhaled nitric oxide in the differentiation of asthma-COPD overlap syndrome, asthma, and COPD[J]. Int J Chron Obstruct Pulmon Dis, 2016,11:2385-2390. DOI: 10.2147/COPD.S115378 .

返回引文位置Google Scholar

百度学术

万方数据

[6]

Bafadhel M , Peterson S , De Blas MA ,et al. Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials[J]. Lancet Respir Med, 2018,6(2):117-126. DOI: 10.1016/S2213-2600(18)30006-7 .

返回引文位置Google Scholar

百度学术

万方数据

[7]

Chapman KR , Hurst JR , Frent SM ,et al. Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial[J]. Am J Respir Crit Care Med, 2018,198(3):329-339. DOI: 10.1164/rccm.201803-0405OC .

返回引文位置Google Scholar

百度学术

万方数据

[8]

GOLD Executive Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (Update 2019)[EB/OL]. http://www.goldCOPD.com. [ 2018-11-07].

返回引文位置Google Scholar

百度学术

万方数据

[9]

Shirai T , Hirai K , Gon Y ,et al. Combined Assessment of Serum Periostin and YKL-40 May Identify Asthma-COPD Overlap[J]. J Allergy Clin Immunol Pract, 2019,7(1):134-145.e1. DOI: 10.1016/j.jaip.2018.06.015 .

返回引文位置Google Scholar

百度学术

万方数据

[10]

Hines KL , Peebles RS . Management of the Asthma-COPD Overlap Syndrome (ACOS): a Review of the Evidence[J]. Curr Allergy Asthma Rep, 2017,17(3):15. DOI: 10.1007/s11882-017-0683-4 .

返回引文位置Google Scholar

百度学术

万方数据

[11]

Joo H , Han D , Lee JH ,et al. Heterogeneity of asthma-COPD overlap syndrome[J]. Int J Chron Obstruct Pulmon Dis, 2017,12:697-703. DOI: 10.2147/COPD.S130943 .

返回引文位置Google Scholar

百度学术

万方数据

[12]

Boulet LP , Hanania NA . The many faces of asthma-chronic obstructive pulmonary disease overlap[J]. Curr Opin Pulm Med, 2019,25(1):1-10. DOI: 10.1097/MCP.0000000000000547 .

返回引文位置Google Scholar

百度学术

万方数据

[13]

Miravitlles M . Diagnosis of asthma-COPD overlap: the five commandments[J]. Eur Respir J, 2017,49(5). DOI: 10.1183/13993003.00506-2017 .

返回引文位置Google Scholar

百度学术

万方数据

备注信息

利益冲突

所有作者均声明不存在利益冲突

评论 （0条）

暂无评论，发表第一条评论抢沙发