论著
ENGLISH ABSTRACT
介入栓塞治疗肺动脉假性动脉瘤伴大咯血的临床疗效分析
王宾
文宠佩
王爱珠
王勇
严阳刚
林志东
作者及单位信息
·
DOI: 10.3760/cma.j.issn.1001-0939.2020.03.017
Endovascular embolization for pulmonary artery pseudoaneurysms with massive hemoptysis
Wang Bin
Wen Chongpei
Wang Aizhu
Wang Yong
Yan Yanggang
Lin Zhidong
Authors Info & Affiliations
Wang Bin
Department of Interventional Radiology, the Second Affiliated Hospital of Hainan Medical University, Haikou 570311, China
Wen Chongpei
Wang Aizhu
Wang Yong
Yan Yanggang
Lin Zhidong
·
DOI: 10.3760/cma.j.issn.1001-0939.2020.03.017
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摘要

目的探讨体肺双途径栓塞治疗肺动脉假性动脉瘤(pulmonary artery pseudoaneurysms,PAPs)伴大咯血的临床疗效及安全性。

方法回顾性分析2016年1月至2018年2月海南医学院第二附属医院收治的经CT血管造影(CT angiography,CTA)/数字减影血管造影(digital subtractive angiography,DSA)证实为PAPs伴大咯血的15例肺结核患者的临床资料。记录相关影像学表现、介入治疗技术和临床止血成功情况,随访1年内咯血复发状况。

结果共发现15个PAPs,肺CTA发现14个,血管造影发现1个。术中仅支气管动脉造影发现6个,仅肺动脉造影发现4个,支气管动脉及肺动脉造影均发现4个,1个体肺动脉造影均未发现。介入栓塞术后咯血有效止血14例,1例患者术中因大咯血窒息导致死亡。患者随访12个月,其中1例患者术后2周复发大咯血行外科切除术;1例咯血术后3个月余复发,再次行介入栓塞后咯血停止。

结论经体肺双途径栓塞治疗肺结核患者PAPs伴大咯血的临床疗效确切,方法可行,但仍有一定风险。

肺动脉;假性动脉瘤;咯血;栓塞,治疗性;血管造影术
ABSTRACT

ObjectiveTo investigate the efficacy and safety of transcatheter embolization for the treatment of pulmonary artery pseudoaneurysms (PAPs) with massive hemoptysis via both arterial and venous access.

MethodsThe clinical data of 15 patients of pulmonary tuberculosis presenting with massive hemoptysis, who were confirmed by CTA/DSA with PAPs at the Second Affiliated Hospital of Hainan Medical University from January 2016 to February 2018, were retrospectively analyzed. The imaging presentation, technical and clinical success of endovascular treatment, and recurrence of hemoptysis within 1 year was recorded.

ResultsA total of 15 PAPs were involved. Fourteen PAPs were confirmed by pulmonary CTA and one by angiography. Six PAPs were visualized during bronchial artery angiography, 4 PAPs during pulmonary artery angiography, and 4 PAPs both. One PAP was not shown during catheter-directed angiography. Except for one patient who died of asphyxia due to severe hemoptysis undergoing embolization, hemoptysis relapse was achieved in 14 patients after endovascular treatment. During 12 months follow-up, one patient underwent surgical resection because of recurrent hemoptysis 2 weeks after embolization, and another patient with recurrence hemoptysis 3 months after embolization received repeated intervention and hemoptysis relapsed.

ConclusionTranscatheter embolization via dual access is effective and feasible for the treatment of PAPs with massive hemoptysis in patients with pulmonary tuberculosis, but still some risks.

Pulmonary artery;Pseudoaneurysm;Hemoptysis;Embolization, therapeutic;Angiography
Lin Zhidong, Email: mocdef.3ab61gnodihznil
引用本文

王宾,文宠佩,王爱珠,等. 介入栓塞治疗肺动脉假性动脉瘤伴大咯血的临床疗效分析[J]. 中华结核和呼吸杂志,2020,43(03):223-227.

DOI:10.3760/cma.j.issn.1001-0939.2020.03.017

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*以上评分为匿名评价
咯血是肺结核患者常见且较严重的并发症,尤其是大咯血(>300 ml/24 h或100 ml/次)患者的病死率高达50% [ 1 ],是需要紧急干预的临床急症。目前对于支气管动脉及非支气管动脉体循环分支动脉(统称支气管动脉)栓塞已成为治疗咯血的首选方法,其临床疗效可靠 [ 2 ]。但部分患者经支气管动脉栓塞后仍继续咯血,此时应想到肺源性咯血可能,文献报道 [ 3 ]其发病率较低,约5%~10%,最主要原因是肺动脉假性动脉瘤(pulmonary artery pseudoaneurysms,PAPs)。国内外文献对于PAPs治疗的报道不多 [ 1 , 4 , 5 ],且治疗方式各异。本研究回顾性分析海南医学院第二附属医院收治的肺结核大咯血伴PAPs患者的临床资料,对PAPs的诊断及体肺双途径栓塞治疗疗效进行探讨。
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备注信息
A
林志东,Email: mocdef.3ab61gnodihznil
B

王宾及文宠佩完成本研究设计、实施及文章撰写;王爱珠及严阳刚完成本研究数据收集及统计分析;王勇及林志东完成对本研究行批评性审阅及工作支持

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