综述
ENGLISH ABSTRACT
飞秒激光角膜屈光手术生物力学效应研究进展
张耀花
王雁 [综述]
作者及单位信息
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DOI: 10.3760/cma.j.cn115989-20200512-00339
Advances in biomechanical effects of femtosecond laser corneal refractive surgery
Zhang Yaohua
Wang Yan
Authors Info & Affiliations
Zhang Yaohua
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China
Wang Yan
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China
·
DOI: 10.3760/cma.j.cn115989-20200512-00339
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摘要

飞秒激光以其独特的优势广泛应用于角膜屈光手术。角膜屈光手术通过切削角膜来改变屈光状态的同时也改变了角膜的组织结构及其生物力学特性,不同的手术方式对角膜生物力学的改变也有所不同。目前临床上常用的飞秒激光角膜屈光手术有飞秒激光辅助的角膜原位磨镶术(FS-LASIK)和飞秒激光小切口角膜基质透镜取出术(SMILE)。本文就角膜生物力学特性的结构基础,目前常用的角膜生物力学测量方法,FS-LASIK手术中瓣厚度、侧切角度、残余基质床厚度、瓣蒂方向等参数的设置,及SMILE手术中切口大小、光学区大小、帽厚度、组织切削量等参数的设置对角膜生物力学的影响进行综述。

飞秒激光;屈光手术;角膜生物力学;飞秒激光辅助的角膜原位磨镶术;飞秒激光小切口角膜基质透镜取出术
ABSTRACT

Femtosecond laser has been widely used in corneal refractive surgery.The refractive state, corneal tissue structure and biomechanical properties are changed through cutting the corneal tissue.Femtosecond laser-assisted in situ keratomileusis(FS-LASIK)and small incision lenticule extraction(SMILE)are the most commonly used femtosecond laser corneal refractive surgery.In this study, the structural basis of corneal biomechanical properties, the commonly used methods for corneal biomechanics measuring, biomechanical effect of corneal flap thickness, side-cut angles, residual stromal bed thickness, flap hinge position for F-LASIK and the size of corneal incision, optical zone diameter, cap thickness, tissue cutting thickness for SMILE on corneal biomechanics are reviewed.

Femtosecond laser;Refractive surgery;Biomechanics;Femtosecond laser-assisted in situ keratomileusis;Small incision lenticule extraction
Wang Yan, Email: mocdef.aabnis.piv3417naygnaw
引用本文

张耀花,王雁. 飞秒激光角膜屈光手术生物力学效应研究进展[J]. 中华实验眼科杂志,2020,38(06):534-538.

DOI:10.3760/cma.j.cn115989-20200512-00339

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目前,近视眼患病率呈升高趋势 [ 1 , 2 ],人们对近视矫正的需求越来越多。飞秒激光以其高精准性和安全性等优势被广泛运用于近视矫正 [ 3 ],然而,角膜扩张是角膜屈光手术后罕见但较为严重的并发症 [ 4 ]。研究表明,角膜扩张的发生和发展与角膜生物力学特性密切相关 [ 5 ]。角膜组织的切削会导致角膜生物力学特性的改变,不同的手术方式对角膜生物力学特性的影响不同。了解各种术式的角膜生物力学变化有助于临床医师对术式的选择及手术的设计以优化手术结果。本文就飞秒激光角膜屈光手术生物力学效应的研究进展进行综述。
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王雁,Email: mocdef.aabnis.piv3417naygnaw
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所有作者均声明不存在利益冲突
C
国家自然科学基金项目 (81670884)
天津市应用基础与前沿技术研究计划重点项目 (14JCZDJC35900)
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