目的观察自体细胞再生技术治疗深度烧伤削痂后植皮的效果。
方法分析2014年3月至2018年3月我科住院的深度烧伤患者54例，其中27例患者术中应用自体细胞再生技术（细胞分选仪，广州市麦施缔医疗科技有限公司，粤穗械备：20201238号）结合游离皮片移植，27例患者常规使用游离皮片移植修复创面。于术后对比两组创面的愈合时间和愈合效果。
结果应用自体细胞再生技术结合植皮后，与对照组相比，实验组愈合时间更短愈合后远期效果更佳，两组差异有统计学意义（P<0.05）。在术后首次换药时疼痛程度，术后植皮并发症方面，两组之间差异无统计学意义。
结论自体细胞再生技术可有效促进烧伤创面愈合，缩短愈合时间，并且安全性高。
ObjectiveTo investigate the outcomes of skin grafting aided with autologous cell regeneration technique for treatment of deep burn wounds following tangential excision of eschars.
MethodsIncluded in this study were a total of 54 patients with deep burns hospitalized in our department between March 2014 and March 2018. Among them, 27 patients (study group) underwent free skin grafting aided with autologous cell regeneration technique (MYSEED ®kit) , and the other 27 (control group) received conventional free skin grafting, for wound repair. The wound healing time and healing outcome after operation were compared between the two groups.
ResultsCompared with the control group, use of autologous cell regeneration technique lead to shorter healing time and better long-term outcome after wound healing in the study group, with statistically significant difference between groups ( P<0.05) . The two groups did not differ statistically in terms of pain during the first dressing change and postoperative complications of the skin grafting.
ConclusionUse of autologous cell regeneration technique can effectively promote healing of burn wounds and shorten the healing time, with high patient safety profiles.
胡志成,张逸,唐冰,等. 深度烧伤创面削痂后植皮结合自体细胞再生技术治疗的临床研究[J]. 中华生物医学工程杂志,2020,26(06)：536-540.
DOI:10.3760/cma.j.cn115668-20201104-00302版权归中华医学会所有。
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