目的了解拉萨地区藏族成年人群眼球生物测量值的分布及影响因素。
方法采用横断面研究设计，连续收集2017年3—7月就诊于西藏自治区人民医院进行眼球生物测量的拉萨地区藏族成年白内障患者100例100眼，其中男51例，女49例；平均年龄(63.38±12.80)岁。以60岁为年龄界限划分，60岁以上57例57眼为老年组，60岁以下43例43眼为中青年组。对所有患者进行角膜曲率、角膜散光、前房深度和眼轴长度的测量，并对纳入人群与北京地区人群眼轴长度和不同年龄及性别人群眼球生物测量参数进行比较分析。
结果拉萨地区藏族成年人群的平均角膜曲率、角膜散光、前房深度和眼轴长度分别为(43.68±1.62)D、0.750(0.375，1.000)D、(3.05±0.41)mm和(23.07±0.86)mm。与北京地区人群相比，藏族成年人群眼轴长度明显偏短，差异有统计学意义( t＝2.65， P<0.01)。老年组人群的角膜散光值明显高于中青年组，差异有统计学意义( t＝2.11， P<0.05)；不同年龄组间角膜曲率、前房深度和眼轴长度比较，差异均无统计学意义(均 P>0.05)。男性组前房深度、眼轴长度明显大于女性组，差异均有统计学意义( t＝2.71、2.25，均 P<0.05)；不同性别组间角膜曲率和角膜散光值差异均无统计学意义(均 P>0.05)。
结论藏族成年人群眼轴长度偏短，前房偏深，老年人群角膜散光增加，眼轴长度和前房深度表现出一定的性别差异。
ObjectiveTo investigate the variations in ocular biometry and its influencing factors in adult Tibetans of Lhasa.
MethodsA cross-sectional study was adopted.A total of 100 consecutive adult Tibetans (100 eyes) with cataract, who were treated in Tibet Autonomous Region People's Hospital from March 2017 to July 2017 were enrolled, including 51 males and 49 females, with an average age of (63.38±12.80) years.The subjects were divided into two groups, with 57 subjects (57 eyes) older than 60 years in the elder group and 43 subjects (43 eyes) younger than 60 years in the youth group.Corneal curvature, corneal astigmatism, anterior chamber depth and axial length of subjects were measured and compared with those of Beijing population which were used as standardized data of Han Chinese.The differences in ocular parameters associated with age and gender were analyzed.This study adhered to the Declaration of Helsinki.The study protocol was approved by an Ethics Committee of Tibet Autonomous Region People's Hospital (No.ME-TBHP-21-KJ-005).Written informed consent was obtained from each subject prior to any examination.
ResultsThe mean corneal curvature, corneal astigmatism, anterior chamber depth and axial length of the 100 Tibetans were (43.68±1.62)D, 0.750 (0.375, 1.000)D, (3.05±0.41)mm, (23.07±0.86)mm, respectively.The axial length of Tibetan was shorter than that of Beijing Han people and the difference was significant ( t=2.65, P<0.01).Corneal astigmatism of the elder group was higher than that of youth group and the difference was significant ( t=2.11, P<0.05).There were no significant differences in corneal curvature, anterior chamber depth and axial length between the elder group and youth group (all at P>0.05).The anterior chamber depth and axial length of males were much longer than those of females, and the differences were significant ( t=2.71, 2.25; both at P<0.05).
ConclusionsIn adult Tibetan population, the axial length is short, and the anterior chamber is deep.The corneal astigmatism increases with age and there is a gender difference in axial length and anterior chamber depth.
刘江,次仁琼达,吴元,等. 拉萨地区藏族成年人群眼球生物测量参数分析[J]. 中华实验眼科杂志,2021,39(04)：337-340.
DOI:10.3760/cma.j.cn115989-20210114-00035版权归中华医学会所有。
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