目的探讨尿液、阴道自我取样和妇科医师取样用于宫颈癌筛查的的人群接受度。
方法对2015年和2018年于山西省襄垣县和阳城县参加宫颈癌筛查者进行问卷调查，问卷内容共3部分，分别为受检者在尿液、阴道自我取样和妇科医师取样过程中的主观感受，对不同取样方法的接受度及对自我取样方法的难易程度评价。
结果共收回有效问卷3 485份。在尿液、阴道自我取样和妇科医师取样过程中，分别有2.3%(81/3 472)、7.1%(247/3 472)和8.6%(299/3 472)的受检者感觉尴尬或难为情，1.3%(46/3 472)、9.7%(337/3 472)和14.9%(518/3 472)的受检者感觉不适，1.0%(35/3 469)、8.5%(295/3 469)和15.3%(531/3 469)的受检者感觉疼痛，98.3%(3 334/3 393)、96.3%(3 267/3 393)和99.0%(3 360/3 393)的受检者认为取样操作规范正确(均 P<0.05)。根据取样过程中的感受，66.5%(2 037/3 064)愿意采用妇科医师取样，其次为尿液自我取样(61.2%，1 876/3 064)及阴道自我取样(39.1%，1 199/3 064，均 P<0.05)。若筛查结果准确性相同，在宫颈癌筛查中，愿意采用自我取样、医师取样方法者占比分别为31.8%(1 109/3 485)和68.2%(2 376/3 485)；愿意采用尿液自我取样、阴道自我取样者分别为76.5%(2 662/3 482)和23.5%(820/3 482)。86.5%(3 007/3 478)的受检者认为尿液自我取样非常容易，而仅40.9%(1 423/3 478)认为阴道自我取样非常容易。
结论在尿液自我取样过程中，受检者产生不适感的程度及比例低于妇科医师取样和阴道自我取样。妇科医师取样的人群接受度最高，尿液自我取样次之，阴道自我取样接受度最低。尿液自我取样比阴道自我取样容易。
ObjectiveTo compare the acceptance of urine self-sampling, vaginal self-sampling and physician sampling in cervical cancer screening.
MethodsQuestionnaire surveys were conducted in women attending cervical cancer screening in Xiangyuan County and Yangcheng County in Shanxi Province from July to November 2015 and from October to December 2018. Both surveys included the following three parts: feelings and acceptance of women in urine self-sampling, vaginal self-sampling and physician sampling, and the ease evaluation of two self-samplings.
ResultsThere were 3 485 questionnaires were collected finally. The proportions of women felt embarrassed in urine self-sampling, vaginal self-sampling and physician sampling were 2.3% (81/3 472), 7.1% (247/3 472) and 8.6% (299/3 472), and 1.3% (46/3 472), 9.7%(3 37/3 472) and 14.9% (518/3 472) of women felt uncomfortable, and 1.0% (35/3 469), 8.5% (295/3 469) and 15.3% (531/3 469) felt pain, and 98.3% (3 334/3 393), 96.3% (3 267/3 393) and 99.0% (3 360/3 393) thought that the sampling were conducted properly ( P<0.05). Based on the feeling during sample collection, 61.2% (1 876/3 064), 39.1% (1 199/3 064) and 66.5% (2 037/3 064) women were willing to use the corresponded sampling methods in cervical cancer screening, respectively ( P<0.05). If the accuracy was the same, there were 31.8% (1 109/3 485) women preferred self-sampling and 68.2% (2 376/3 485) preferred physician sampling for cervical cancer screening. Meanwhile, 23.5% (820/3 482) preferred vaginal self-sampling in comparison with 76.5% (2 662/3 482) for urine self-sampling in cervical cancer screening. 86.5% (3 007/3 478) of the women thought urine self-sampling was very easy, comparing 40.9% (1 423/3 478) for vaginal self-sampling.
ConclusionsThe bad feeling of women during urine self-sampling is less common and less serious than those during physician sampling and vaginal self-sampling, and the acceptance for physician sampling is highest, following by urine self-sampling and vaginal self-sampling. Urine self-sampling is much easier than vaginal self-sampling.
徐慧芳,余艳琴,党乐,等. 宫颈癌筛查不同取样方法的人群接受度评价[J]. 中华肿瘤杂志,2021,43(12)：1282-1286.
DOI:10.3760/cma.j.cn112152-20190419-00252版权归中华医学会所有。
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