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ENGLISH ABSTRACT
外科肺活检在弥漫性实质性肺疾病中的价值：再评价与新认识
施举红
作者及单位信息
·
DOI： 10.3760/cma.j.cn112147-20220110-00028
Diagnostic value of surgical lung biopsies for diffuse parenchymal lung disease:re-evaluation and new insight
Shi Juhong
Authors Info & Affiliations
Shi Juhong
Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
·
DOI： 10.3760/cma.j.cn112147-20220110-00028
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摘要

外科肺活检由于能提供更多的信息，对弥漫性实质性肺疾病（DPLD）诊治具有重要价值，被多数指南推荐为确诊的主要手段。然而，随着新的无创或微创等手段在DPLD诊治中的运用，SLB在DPLD诊断中的地位和应用价值需要再评估。

ABSTRACT

Surgical lung biopsy (SLB) has been clearly recommended for the diagnosis of diffuse parenchymal lung disease (DPLD) in major guidelines because it provides the largest and most informative tissue samples. However, with the use of new non-invasive or minimally invasive tools in the diagnosis and treatment of DPLD, the dominance of SLB as the gold standard in the diagnosis of DPLD has been questioned, the diagnostic value of SLB for diffuse parenchymal lung should be re-evaluated.

Shi Juhong, Email: nc.defhcabmuphjihs
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施举红. 外科肺活检在弥漫性实质性肺疾病中的价值：再评价与新认识[J]. 中华结核和呼吸杂志,2022,45(03)：243-246.

DOI:10.3760/cma.j.cn112147-20220110-00028

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弥漫性实质性肺疾病（diffuse parenchymal lung disease，DPLD）是主要累及肺间质和肺泡腔，在影像学上表现为双肺弥漫病变的一组疾病的统称。2002年美国胸科协会和欧洲呼吸病学会关于特发性间质性肺疾病的分类共识中首次提出DPLD的概念 ［ 1 ］ 。DPLD的病因多样，明确诊断有助于精准治疗及判断预后。与支气管镜肺活检和经皮肺穿刺活检相比 ［ 2 , 3 ］ ，外科肺活检（surgical lung biopsy，SLB）可提供更多的诊断信息，对诊治具有重要价值，是DPLD诊断的金标准。但近30年来，随着临床诊治经验的积累和认识加深、诊治策略不断修订与完善，无创或微创等手段在DPLD诊治中的运用日渐增多，因此对SLB在DPLD的诊断价值及地位也需要再评估。结合本期我们团队总结的疾病谱改变 ［ 4 ］ ，现对SLB在临床的应用价值总结如下。
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施举红，Email： nc.defhcabmuphjihs
B

施举红. 外科肺活检在弥漫性实质性肺疾病中的价值：再评价与新认识[J]. 中华结核和呼吸杂志, 2022, 45(3): 243-246. DOI: 10.3760/cma.j.cn112147-20220110-00028.

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