首页 中华结核和呼吸杂志 2022年45卷03期 抗氧化治疗在肺癌合并肺间质病应用中的潜在问题
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抗氧化治疗在肺癌合并肺间质病应用中的潜在问题
陶沛智 
刘娜
郭秀
迟昊
张捷
董春玲 
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DOI： 10.3760/cma.j.cn112147-20211216-00892
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摘要
肺癌（LC）的发病率近些年逐渐上升，与间质性肺疾病（ILD）尤其是特发性肺纤维化（IPF）密切相关。氧化应激是肺恶性肿瘤以及肺间质病的共同病理生理因素之一，近年来，关于抗氧化剂应用于LC-ILD患者的疗效一直倍受学界关注，本文对氧化应激在肺癌和肺间质病中的作用机制进行汇总，探讨抗氧化剂应用于LC-ILD治疗的潜在价值及可能的矛盾性，以期探索该类患者的治疗方案，并为后续研究方向提供部分理论依据。
引用本文
陶沛智,刘娜,郭秀,等. 抗氧化治疗在肺癌合并肺间质病应用中的潜在问题[J]. 中华结核和呼吸杂志,2022,45(03)：318-320.
DOI:10.3760/cma.j.cn112147-20211216-00892PERMISSIONS
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近年来肺癌的发病率逐渐升高，文献报道肺癌与间质性肺疾病（ILD）尤其是特发性肺纤维化（IPF）关系密切。氧化应激是肺部恶性肿瘤以及肺间质病的共同病理生理因素之一，近年来关于抗氧化剂应用于肺癌合并ILD（LC-ILD）患者的疗效一直备受关注，LC-ILD患者并不能完全受益于抗氧化剂和免疫治疗等新的肿瘤治疗方法。本文探讨抗氧化剂应用于LC-ILD治疗的潜在价值及可能存在的矛盾，探索LC-ILD患者的治疗和研究方向。
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备注信息
A
董春玲，Email：
nc.defudabe.uljgnodlc
B
陶沛智, 刘娜, 郭秀, 等. 抗氧化治疗在肺癌合并肺间质病应用中的潜在问题[J]. 中华结核和呼吸杂志, 2022, 45(3): 318-320. DOI: 10.3760/cma.j.cn112147-20211216-00892.
C
所有作者声明无利益冲突
D
吉林省财政厅卫生专项项目 (2020SCZT023，3D5177713429)
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