首页 中华肿瘤杂志 2022年44卷06期 中国食管癌筛查与早诊早治指南(2022，北京)
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中国食管癌筛查与早诊早治指南(2022，北京)
赫捷 
陈万青
李兆申
李霓
任建松
田金徽
田文静
胡付兰
彭绩
中国食管癌筛查与早诊早治指南制定专家组
中国食管癌筛查与早诊早治指南制定工作组
作者及单位信息
·
DOI： 10.3760/cma.j.cn112152-20220517-00348
China guideline for the screening, early detection and early treatment of esophageal cancer (2022, Beijing)
He Jie
Chen Wanqing
Li Zhaoshen
Li Ni
Ren Jiansong
Tian Jinhui
Tian Wenjing
Hu Fulan
Peng Ji
Expert Group of China Guideline for the Screening, Early Detection and Early Treatment of Esophageal Cancer
Work Group of China Guideline for the Screening,Early Detection and Early Treatment of Esophageal Cancer
Authors Info & Affiliations
He Jie
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Chen Wanqing
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Li Zhaoshen
Changhai Hospital, Shanghai 200433, China
Li Ni
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Ren Jiansong
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Tian Jinhui
Evidence-Based Medicine Center, Lanzhou University, Lanzhou 730000, China
Tian Wenjing
Public Health College of Harbin Medical University, Harbin 150081, China
Hu Fulan
School of Public Health, Shenzhen University Health Science Center, Shenzhen 518037, China
Peng Ji
Shenzhen Centre for Chronic Disease Control, Shenzhen 518020, China
Expert Group of China Guideline for the Screening, Early Detection and Early Treatment of Esophageal Cancer
Work Group of China Guideline for the Screening,Early Detection and Early Treatment of Esophageal Cancer
·
DOI： 10.3760/cma.j.cn112152-20220517-00348
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摘要
食管癌是我国常见的消化道恶性肿瘤之一，严重威胁我国居民生命健康。食管癌高风险人群接受筛查和早诊早治能够有效降低食管癌的发病率和死亡率。制定符合中国国情的食管癌筛查与早诊早治指南，将促进中国食管癌筛查的同质性和规范性，提高食管癌筛查的效果。中国食管癌筛查与早诊早治指南受国家卫生健康委员会疾病预防控制局的委托与指导，由国家癌症中心发起，联合多学科专家，整合食管癌筛查与早诊早治领域的国内外研究进展，同时考虑中国国情和食管癌筛查的实际经验，根据世界卫生组织推荐的指南制定原则和方法，针对食管癌筛查过程中的筛查人群、技术、流程等给出了基于证据的推荐，旨在保证食管癌筛查与早诊早治效果，为中国的食管癌防控提供科学依据。
食管肿瘤;筛查;早诊早治;指南;中国
ABSTRACT
Esophageal cancer (EC) is a major digestive tract malignancy in China, which seriously threatens the health of Chinese population. A large number of researches have demonstrated that screening and early detection are effective in reducing the incidence and mortality of EC. The development of the guideline for EC screening and early detection in line with epidemic characteristics of EC in China will greatly promote the homogeneity and standardization, and improve the effect of EC screening. This guideline was commissioned by the Bureau of Disease Control and Prevention of the National Health Commission. The National Cancer Center of China initiated and convened a working group comprising multidisciplinary experts. Following the World Health Organization Handbook for Guideline Development, this guideline combined the most up-to-date evidence of EC screening, China′s national conditions, and practical experience in cancer screening. This guideline provided evidence-based recommendations with respect to the screening population, technology and procedure management, aiming to improve the effect of EC screening and provide scientific evidence for the EC prevention and control in China.
Esophageal neoplasms;Screening;Early diagnosis and early treatment;Guideline;China
He Jie, Email:
nc.defcaab.smaciceijeh
He Jie and Chen Wanqing contributed equally to this article
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引用本文
赫捷,陈万青,李兆申,等. 中国食管癌筛查与早诊早治指南(2022，北京)[J]. 中华肿瘤杂志,2022,44(06)：491-522.
DOI:10.3760/cma.j.cn112152-20220517-00348PERMISSIONS
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一、引言
食管癌是威胁我国居民生命健康的主要恶性肿瘤之一。世界卫生组织数据显示，2020年我国食管癌新发病例为32.4万例，死亡病例为30.1万例，分别占全球食管癌发病与死亡的53.70%和55.35%
[
1
]。食管癌严重威胁我国居民生命健康，如何有效降低食管癌疾病负担也是我国重大公共卫生问题之一。
按照组织类型分类，食管癌主要分为食管鳞状细胞癌和食管腺癌，在我国以食管鳞状细胞癌为主
[
2
]。食管癌早期患者缺乏典型的临床症状和体征，大多数患者就诊时已达肿瘤中晚期，导致我国食管癌患者的总体预后较差。2003—2015年间，尽管我国食管癌年龄标化5年生存率从20.9%上升到30.3%，但总体5年生存率仍偏低
[
3
]。食管癌患者的生存时间与其临床分期密切相关，早期食管癌患者在接受治疗后5年生存率可达95%
[
4
]。目前已有多项研究表明，针对食管癌高风险人群开展筛查能够有效降低食管癌的发病率和死亡率
[
5
,
6
]。我国的食管癌筛查始于20世纪70年代，并于21世纪迅速发展。目前，我国已开展包括食管癌筛查在内的多个重大公共卫生项目，均取得了较好的社会效益。
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备注信息
A
赫捷，Email:
nc.defcaab.smaciceijeh
B
赫捷和陈万青对本文有同等贡献
C
感谢以下专家在本指南制定过程中提出的宝贵建议(以姓氏汉语拼音排序)安俊平(徐州市肿瘤医院)、郭嫦媛(国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院)、刘亚洲(徐州市肿瘤医院)、王洛伟(上海长海医院)、王慜杰(国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院)、薛学敏(国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院)
D
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