首页 中华肿瘤杂志 2022年44卷07期 中国胃癌筛查与早诊早治指南(2022，北京)
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中国胃癌筛查与早诊早治指南(2022，北京)
赫捷 
陈万青
李兆申
李霓
任建松
田金徽
田文静
胡付兰
彭绩
中国胃癌筛查与早诊早治指南制定专家组
中国胃癌筛查与早诊早治指南制定工作组
作者及单位信息
·
DOI： 10.3760/cma.j.cn112152-20220617-00430
China guideline for the screening, early detection and early treatment of gastric cancer (2022, Beijing)
He Jie
Chen Wanqing
Li Zhaoshen
Li Ni
Ren Jiansong
Tian Jinhui
Tian Wenjing
Hu Fulan
Peng Ji
Expert Group of China Guideline for the Screening,Early Detection and Early Treatment of Gastric Cancer;
Working Group of China Guideline for the Screening, Early Detection and Early Treatment of Gastric Cancer
Authors Info & Affiliations
He Jie
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Chen Wanqing
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Li Zhaoshen
The First Affiliated Hos-pital of Naval Medical University, Shanghai 200433, China
Li Ni
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Ren Jiansong
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Tian Jinhui
Evidence Based Medicine Center, Lanzhou University, Lanzhou 730000, China
Tian Wenjing
Public Health College of Harbin Medical University, Harbin 150081, China
Hu Fulan
School of Public Health, Shenzhen University Health Science Center, Shenzhen 518037, China
Peng Ji
Shenzhen Centre for Chronic Disease Control, Shenzhen 518020, China
Expert Group of China Guideline for the Screening,Early Detection and Early Treatment of Gastric Cancer;
Working Group of China Guideline for the Screening, Early Detection and Early Treatment of Gastric Cancer
·
DOI： 10.3760/cma.j.cn112152-20220617-00430
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摘要
胃癌是中国常见的恶性肿瘤之一，严重威胁居民生命健康。胃癌高风险人群接受筛查和早诊、早治能够有效降低胃癌的发病率和死亡率。制定符合中国国情的胃癌筛查与早诊早治指南，将促进中国胃癌筛查的同质性和规范性，提高胃癌筛查的效果。中国胃癌筛查与早诊早治指南受国家卫生健康委员会疾病预防控制局的委托与指导，由国家癌症中心发起，联合多学科专家，整合胃癌筛查与早诊早治领域的国内外研究进展，同时考虑中国国情和胃癌筛查的实际经验，根据世界卫生组织推荐的指南制定原则和方法，针对胃癌筛查过程中的筛查人群、技术、流程等给出了基于证据的推荐，旨在保证胃癌筛查与早诊早治效果，为中国的胃癌防控提供科学依据。
胃肿瘤;筛查;早诊早治;指南;中国
ABSTRACT
Gastric cancer (GC) is a major digestive tract malignancy in China, which seriously threatens the health of Chinese population. A large number of researches have demons-trated that screening, early detection and early treatment are effective in reducing the incidence and mortality of GC. The development of the guideline for GC screening, early detection and early treatment in line with epidemic characteristics of GC in China will greatly promote the homogeneity and standardization, and improve the effect of GC screening. This guideline was commissioned by the Bureau of Disease Control and Prevention of the National Health Commission. The National Cancer Center of China initiated and convened a working group comprising multidisciplinary experts. Following the World Health Organization Handbook for Guideline Development, this guideline combined the most up-to-date evidence of GC screening, China′s national conditions, and practical experience in cancer screening. This guideline provided evidence-based recommendations with respect to the screening population, technology and procedure management, aiming to improve the effect of GC screening and provide scientific evidence for the GC prevention and control in China.
Gastric neoplasms;Screening;Early diagnosis and early treatment;Guide-line;China
He Jie, Email:
nc.defcaab.smaciceijeh
He Jie and Chen Wanqing contributed equally to this article
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引用本文
赫捷,陈万青,李兆申,等. 中国胃癌筛查与早诊早治指南(2022，北京)[J]. 中华肿瘤杂志,2022,44(07)：634-666.
DOI:10.3760/cma.j.cn112152-20220617-00430PERMISSIONS
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一、引言
胃癌是威胁我国居民生命健康的主要恶性肿瘤之一。世界卫生组织(World Health Organization, WHO)数据显示，2020年我国胃癌新发病例47.9万例，死亡病例37.4万例，分别占全球胃癌新发和死亡病例的44.0%和48.6%
[
1
]。在我国，胃癌发病率位列恶性肿瘤发病率的第4位，死亡率的第3位，严重威胁人民群众的生命健康，成为我国重大的公共卫生问题
[
1
]。胃癌防治是我国恶性肿瘤防控面临的重大挑战。
2003—2015年，我国胃癌5年相对生存率有所升高，从27.4%提高至35.1%，但仍然明显低于日本(80.1%)
[
2
]和韩国(75.4%)
[
3
]。胃癌患者的生存时间与其临床诊断发现的早晚密切相关。胃癌早期症状不明显，多数患者在确诊时已处于中晚期，即使接受手术治疗的患者5年生存率仍<30%，而早期患者经过及时治疗5年生存率可>90%
[
4
,
5
,
6
]。
开展胃癌筛查可显著提高胃癌早期病变检出率，改善患者预后，大幅提高患者生存率。民众对于胃癌及其筛查的认知程度低等现状制约着我国胃癌筛查与早诊早治工作的效果与收益。我国目前已发布多部胃癌筛查与早诊早治相关的专家共识
[
7
,
8
,
9
]，但尚缺乏基于循证医学证据的胃癌筛查与早诊早治指南。为了推进我国胃癌筛查工作的规范化、均质化和优质化，国家癌症中心成立中国胃癌筛查与早诊早治指南制定专家组，联合肿瘤学、消化内科学、内镜学、外科学、病理学、临床检验学、流行病学、循证医学、卫生经济学和卫生管理学等多学科专家，基于WHO推荐的指南制定原则和方法，制定符合我国国情的胃癌筛查与早诊早治指南，以期为我国胃癌筛查与早诊早治的规范开展提供参考。
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备注信息
A
赫捷，Email：
nc.defcaab.smaciceijeh
B
赫捷和陈万青对本文有同等贡献
C
感谢以下专家在本指南制定过程中提出的宝贵建议(按姓氏汉语拼音字母排序) 安俊平(徐州市肿瘤医院)、郭嫦媛(国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院)、李琳(国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院)、刘亚洲(徐州市肿瘤医院)、王洛伟(海军军医大学第一附属医院)、王慜杰(国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院)、薛学敏(国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院)参
D
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