临床论著
ENGLISH ABSTRACT
JeRP钢板与微型钛板经口咽入路单节段固定治疗不稳定型寰椎骨折的疗效比较
涂强
陈虎
孙昊
黄显华
朱昌荣
马向阳
王建华
章凯
尹庆水
夏虹
作者及单位信息
·
DOI: 10.3760/cma.j.cn115530-20220523-00280
Comparison of Jefferson-fracture reduction plate and micro titanium plate in the transoral single-segment fixation of unstable atlas fractures
Tu Qiang
Chen Hu
Sun Hao
Huang Xianhua
Zhu Changrong
Ma Xiangyang
Wang Jianhua
Zhang Kai
Yin Qingshui
Xia Hong
Authors Info & Affiliations
Tu Qiang
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
The First Clinical Medical College of Southern Medical University, Guangzhou 510010, China
Guangzhou University of Chinese Medicine, Guangzhou 510010, China
Chen Hu
The First Clinical Medical College of Southern Medical University, Guangzhou 510010, China
Sun Hao
Guangzhou University of Chinese Medicine, Guangzhou 510010, China
Huang Xianhua
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Zhu Changrong
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Ma Xiangyang
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Wang Jianhua
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Zhang Kai
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Yin Qingshui
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
Xia Hong
Department of Orthopedic Surgery, General Hospital of Southern Theatre Command, Guangzhou 510010, China
·
DOI: 10.3760/cma.j.cn115530-20220523-00280
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摘要

目的比较JeRP钢板与微型钛板经口咽入路单节段固定治疗不稳定型寰椎骨折的疗效。

方法回顾性分析2008年1月至2020年12月中国人民解放军南部战区总医院骨科收治的45例不稳定型寰椎骨折患者资料。男24例,女21例;年龄15~67岁;寰椎骨折Gehweiler分型:Ⅰ型11例,Ⅲ型34例;美国脊髓损伤协会(ASIA)脊髓损伤分级:D级7例,E级38例;寰椎横韧带损伤的Dickman分型:Ⅰ型4例,Ⅱ型11例。将所有患者根据治疗方法不同分为2组:JeRP钢板组26例(采用JeRP钢板经口咽入路单节段固定治疗)和微型钛板组19例(采用微型钛板经口咽入路单节段固定治疗)。记录并比较两组患者基线资料、手术时间、出血量、住院时间、术前和末次随访时颈部疼痛视觉模拟评分(VAS)、寰椎侧块位移的距离(LMD)及术中、术后并发症发生情况。

结果两组术前一般资料比较差异均无统计学意义( P>0.05),具有可比性。所有患者术后获12~55个月(平均21.8个月)随访。所有患者术后均未出现伤口裂开、感染。术后12个月左右所有患者骨折均获骨性愈合,颈部疼痛基本消失,颈部活动无明显受限。JeRP钢板组与微型钛板组患者住院时间分别为(13.9±2.2)、(14.2±2.9)d,两组间比较差异无统计学意义( P>0.05)。JeRP钢板组患者手术时间为(203.5±173.4)min,出血量为(167.3±138.6)mL,均显著多于微型钛板组的(121.5±50.5)min、(98.4±57.2)mL,两组间比较差异均有统计学意义( P<0.05)。JeRP钢板组术前LMD为(6.7±1.7)mm,VAS评分为(6.8±1.0)分,显著大于末次随访时的(0.7±0.6)mm、(0.7±0.6)分,差异均有统计学意义( P<0.05)。微型钛板组术前LMD为(6.6±1.5)mm,VAS评分为(6.7±0.9)分,显著大于末次随访时的(0.9±0.6)mm、(0.8±0.7)分,差异均有统计学意义( P<0.05)。但以上指标术前、末次随访时两组间比较差异均无统计学意义( P>0.05)。JeRP组有1例患者术后1周发现内固定物松动。微型钛板组有1例患者术后出现咽喉部异物感。

结论经口咽入路寰椎单节段JeRP钢板与微型钛板固定均能有效治疗不稳定型寰椎骨折。相对JeRP钢板,微型钛板小巧、切迹低,能有效缩短手术时间,降低出血量。

寰枢关节;寰枕关节;脊髓损伤;经口咽入路;寰椎骨折;JeRP钢板;微型钛板
ABSTRACT

ObjectiveTo compare Jefferson-fracture reduction plate (JeRP) and micro titanium plate in the transoral single-segment fixation of unstable atlas fractures.

MethodsFrom January 2008 to December 2020, 45 patients with unstable atlas fracture were treated by single-segment fixation through an oral approach with a JeRP or a micro titanium plate at Department of Orthopedic Surgery, General Hospital of Southern Theatre Command. They were 24 males and 21 females, aged from 15 to 67 years. By the Gehweiler classification, 11 atlas fractures were type Ⅰ and 34 type Ⅲ; by the American Spinal Injury Association (ASIA) classification, the spinal cord injury was grade D in 7 cases and grade E in 38 cases; by the Dickman classification, the atlas transverse ligament injury was type Ⅰ in 4 cases and type Ⅱ in 11 cases. Of the patients, 26 were treated by transoral single-segment fixation with a JeRP and 19 by transoral single-segment fixation with a micro titanium plate. The 2 groups were compared in terms of baseline data, operation time, blood loss, hospital stay, visual analog scale (VAS) for neck pain and atlas lateral mass displacement (LMD) before operation and at the last follow-up, and intraoperative and postoperative complications.

ResultsThe 2 groups were comparable because there was no significant difference between them in the preoperative general data ( P>0.05). All patients were followed up for 12 to 55 months (mean, 21.8 months). Wound dehiscence or infection was observed in none of the patients after operation. About 12 months after operation, all fractures achieved bony union, neck pain basically disappeared, and neck movement had no obvious limitation. The hospital stay was (13.9±2.2) d for the JeRP group and (14.2±2.9) d for the micro titanium plate group, showing no significant difference between the 2 groups ( P>0.05). The operation time was (203.5±173.4) min and the blood loss (167.3±138.6) mL in the JeRP group, significantly more than those in the micro titanium plate group [(121.5±50.5) min and (98.4±57.2) mL] ( P<0.05). In the JeRP group, the preoperative LMD was (6.7±1.7) mm and the preoperative VAS score (6.8±1.0) points, significantly higher than the last follow-up values [(0.7±0.6) mm and (0.7±0.6) points] ( P<0.05). In the micro titanium plate group, the preoperative LMD was (6.6±1.5) mm and the preoperative VAS score (6.7±0.9) points, significantly higher than the last follow-up values [(0.9±0.6) mm and (0.8±0.7) points] ( P<0.05). However, there was no significant difference in the preoperative or the last follow-up comparison between the 2 groups ( P>0.05). Implant loosening was observed in one patient in the JeRP group while foreign body sensation in the throat was reported in one patient after operation in the micro titanium plate group.

ConclusionsBoth JeRP and micro titanium plate in the transoral single-segment fixation can lead to effective treatment of unstable atlas fractures. Compared with JeRP, the micro titanium plate can effectively shorten operation time and reduce blood loss due to its smaller size and lower incision.

Atlanto-axial joint;Atlanto-occipital joint;Spinal cord injuries;Transoral pharyngeal approach;Atlas fractures;Jefferson-fracture reduction plate (JeRP);Micro titanium plate
Xia Hong, Email: mocdef.6ab212gnohaixzg
引用本文

涂强,陈虎,孙昊,等. JeRP钢板与微型钛板经口咽入路单节段固定治疗不稳定型寰椎骨折的疗效比较[J]. 中华创伤骨科杂志,2022,24(11):957-964.

DOI:10.3760/cma.j.cn115530-20220523-00280

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寰椎是头颅与颈椎联系的枢纽,具有独特的环状结构,没有椎体及棘突,与脊柱的其他椎骨相比,其具有更大的灵活性和更大的运动范围。作为枕-寰-枢复合体中的一种过渡结构,寰椎可以将轴向载荷从枕骨传递到枢椎。当轴向暴力从枕骨髁自上而下传递至楔形结构的寰椎侧块时,会转化为水平向外的应力,导致寰椎发生骨折。随着交通事故伤、高处坠落伤等高能量损伤的增多,寰椎骨折发病率逐年递增,约占颈椎骨折的10%。寰椎骨折的治疗目标是使骨折获得骨性愈合,保持枕-寰-枢复合体的稳定,防止出现任何神经功能损害及骨不连、畸形愈合导致的后遗症,最终获得良好的功能 [ 1 , 2 ]。对于不稳定型骨折可采取Halo架、硬质颈托、头颈胸支具等外固定,治疗过程漫长且痛苦。而且保守措施常导致骨折断端得不到满意的复位,治疗效果往往不理想,可能发生骨不连或畸形愈合。因此不稳定型寰椎骨折常常需要行手术治疗,后路寰枢椎融合术或枕颈融合术是治疗寰椎骨折的经典术式,但它牺牲了上颈椎运动功能,明显降低了患者术后生活质量。为了保留寰椎骨折患者上颈椎的运动功能,有学者提出采用单节段固定治疗不稳定型寰椎骨折,称之为"生理性固定",可分为后路和前路经口咽入路 [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ]。后路单节段固定虽然可借助器械横向加压,但对于前弓骨折断端的复位,常常不理想。而前路经口咽入路单节段固定,可以直视下复位前弓骨折断端,效果更直接、更满意 [ 3 , 4 , 5 , 6 , 7 ]
2004年Ruf等 [ 13 ]首次介绍了经口咽入路通过侧块螺钉系统单节段固定治疗寰椎骨折。2006年焦云龙和尹庆水 [ 14 ]研制出具有即时复位功能的寰椎骨折复位钢板(Jefferson-fracture reduction plate,JeRP)内固定系统,夏虹等 [ 11 ]不断改进该型钢板( 图1 ),用于治疗不稳定型寰椎骨折获得了满意疗效。但在临床实践中,我们还采用体积及形态更小巧的微型钛板治疗寰椎骨折( 图1 )。两种钢板在治疗寰椎骨折时是否存在临床疗效的差异暂不明确。本研究回顾性分析2008年1月至2020年12月收治的45例不稳定型寰椎骨折患者资料,旨在比较口咽入路JeRP钢板系统与微型钛板系统治疗不稳定寰椎骨折的疗效,为临床提供参考。
2种钢板正面观(A)及侧面观(B):a为微型钛板,b为JeRP钢板;钢板配套配套螺钉(C):c为微型钛板螺钉,d为JeRP钢板螺钉
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备注信息
A
夏虹,Email: mocdef.6ab212gnohaixzg
B

涂强:课题设计、临床操作、数据采集、论文撰写;陈虎、孙昊、黄显华、朱昌荣:数据采集、数据处理;马向阳:研究指导、论文修改;王建华、章凯、尹庆水:研究指导;夏虹:论文修改

C
所有作者声明无利益冲突
D
军队医学科技青年培育计划孵化项目 (19QNP040)
军队后勤科研计划项目 (CLB20J033)
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