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ENGLISH ABSTRACT
中国病毒性角膜内皮炎诊疗专家共识（2023年）
中国医师协会眼科医师分会眼感染学组
作者及单位信息
·
DOI： 10.3760/cma.j.cn112142-20220407-00163
Chinese expert consensus on diagnosis and treatment of viral corneal endotheliitis (2023)
Ocular Infection Group of Chinese Ophthalmologist Association
Hong Jing
Authors Info & Affiliations
Ocular Infection Group of Chinese Ophthalmologist Association
Hong Jing
Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China
·
DOI： 10.3760/cma.j.cn112142-20220407-00163
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摘要

病毒性角膜内皮炎是一种致盲性角膜病，因临床表现多样，病情复杂，诊断标准不明确以及眼部病毒检测手段有限等原因，易误诊或漏诊，且目前尚缺乏统一和规范的治疗方案。鉴于此，中国医师协会眼科医师分会眼感染学组汇集国内眼感染和角膜病专家，以国内外相关最新研究为基础，参考国内相关专家的临床经验，经过充分讨论，针对病毒性角膜内皮炎的临床诊疗形成共识性意见，以期为临床开展工作提供参考和指导。

角膜炎;眼感染， 病毒性;诊疗准则（主题）
ABSTRACT

Viral corneal endotheliitis, a blinding corneal disease, is often misdiagnosed due to the diverse clinical manifestations, complex conditions, unclear diagnostic criteria, and limited methods of ocular virus detection. In addition, there is still a lack of unified and standardized treatment for viral corneal endotheliitis. The consensus, basing upon the latest research progress and expert recommendations regarding the clinical care of patients with viral corneal endotheliitis, targets to offer best practice advice for the clinical management of viral corneal endotheliitis and has been fully discussed by the experts of the Ocular Infection Group of Chinese Ophthalmologist Association.

Keratitis;Eye infections, viral;Practice guidelines as topic
Hong Jing, Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China, Email: mocdef.aabnis4691gnijgnoh
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引用本文

中国医师协会眼科医师分会眼感染学组. 中国病毒性角膜内皮炎诊疗专家共识（2023年）[J]. 中华眼科杂志,2023,59(01)：13-19.

DOI:10.3760/cma.j.cn112142-20220407-00163

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病毒性角膜炎是导致单眼角膜盲的主要病因之一。流行病学调查表明我国病毒性角膜炎发病率为0.110%~0.148% ［ 1 , 2 ］ ，无论发达国家还是发展中国家，单纯疱疹病毒（herpes simplex virus，HSV）角膜炎最为常见，发病率为5.3/100万至31.5/100万，复发病例比新发病例多1.2~1.5倍 ［ 3 ］ 。相较于HSV和水痘-带状疱疹病毒（varicella-kerpes zoster virus，VZV），巨细胞病毒（cytomegalovirus，CMV）角膜炎在西方国家少见，在亚洲国家发生更为普遍，且发病数量逐年增加 ［ 4 , 5 ］ 。病毒性角膜炎可表现为角膜上皮炎、基质炎、内皮炎、神经营养性角膜病变。
病毒性角膜内皮炎是一种严重的致盲性角膜病 ［ 6 , 7 ］ ，因临床表现多样，病情复杂，诊断标准不明确以及眼部病毒检测手段有限等原因，易漏诊、误诊和误治。若得到及时有效诊疗，预后则较好；若治疗不及时或不当，将导致角膜内皮细胞数量急剧减少，甚至发生角膜内皮功能失代偿。目前病毒性角膜内皮炎尚缺乏统一和规范的治疗方案。鉴于此，中国医师协会眼科医师分会眼感染学组汇集国内眼感染和角膜病专家，以国内外相关最新研究进展为基础，参考国内相关专家的临床经验，经过充分讨论，针对病毒性角膜内皮炎的临床诊疗形成共识性意见，以期为临床开展工作提供参考和指导。
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备注信息
A
洪晶，北京大学第三医院眼科 眼部神经损伤的重建保护与康复北京市重点实验室，北京100191，Email： mocdef.aabnis4691gnijgnoh
B
中国医师协会眼科医师分会眼感染学组. 中国病毒性角膜内皮炎诊疗专家共识（2023年）[J]. 中华眼科杂志, 2023, 59(1): 13-19. DOI: 10.3760/cma.j.cn112142-20220407-00163.
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