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ENGLISH ABSTRACT
纠正生长发育不平衡 预防儿童青少年重要共病
宋逸
马军
作者及单位信息
·
DOI: 10.3760/cma.j.cn112150-20221006-00962
Correct the imbalance of growth and development and prevent important comorbidities of children and adolescents
Song Yi
Ma Jun
Authors Info & Affiliations
Song Yi
Institute of Child and Adolescent Health/School of Public Health, Peking University, Beijing 100191, China
Ma Jun
Institute of Child and Adolescent Health/School of Public Health, Peking University, Beijing 100191, China
·
DOI: 10.3760/cma.j.cn112150-20221006-00962
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摘要

儿童青少年生长发育存在一定的阶段性和连续性,在某些因素诱发下,其生长发育偏离正常规律和轨迹,可能会出现各系统不平衡的现象,甚至可导致重要共病的发生。儿童生长发育不平衡可能是导致儿童青少年肥胖、近视和心理问题等重要共病发生的内部因素,而环境改变与生长发育不匹配可能是其发生的外部因素。因此,需要在定期监测儿童青少年生长发育各项指标的基础上,找到其生长发育不平衡的影响因素,改善致病环境,揭示致病机制,从根本上预防重要共病的发生。

儿童;青少年;生长发育不平衡;共病
ABSTRACT

There are certain stages and continuities in the growth and development of children and adolescents. Under the induction of some factors, their growth and development may deviate from the normal pattern and trajectory, which may lead to an imbalance of various systems, and even result in the occurrence of significant comorbidities. The imbalance of children′s growth and development might be an internal factor leading to the occurrence of important comorbidities such as obesity, myopia and psychological problems in children and adolescents, while the mismatch between environmental changes and growth and development might be an external factor. Therefore, it is necessary to find the influencing factors of imbalance regarding growth and development based on regular monitoring of the growth and development indicators of children and adolescents, improve the pathogenic environment, reveal the behind mechanism, and fundamentally prevent the important comorbidities.

Child;Adolescent;Growth imbalance;Comorbidities
Ma Jun, Email: nc.defudabe.umjbtnujam
引用本文

宋逸,马军. 纠正生长发育不平衡 预防儿童青少年重要共病[J]. 中华预防医学杂志,2023,57(04):451-456.

DOI:10.3760/cma.j.cn112150-20221006-00962

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儿童青少年生长发育是复杂的生物学现象,是多系统共同参与的过程,涉及生理功能、体格指标、体能素质、认知功能成熟、社会化发展诸多方面 1。儿童青少年生长发育过程存在以下规律:首先,机体按照一般规律正常生长发育,使得发育水平达到一定的成熟度,以完成相应的发育任务;其次,生长发育存在一定的阶段性和连续性,阶段性表现在前一阶段能够为后一阶段的发育准备基础,连续性表现在生长发育过程会遵循正常轨迹而不偏离;最后,机体各方面的生长发育虽不同时发生,但相互协调,整体平衡。个体只有在形态、生理功能、心理素质等方面均达到成年水平才标志着机体成熟,其生长发育进程得以平稳有序完成 2。因此,应该将儿童青少年生长发育的各个方面视为有关联的,相互依赖的,其中任何一方面都不应出现滞后或偏离。
儿童青少年生长发育不平衡是指在某些因素诱发下,儿童青少年生长发育进程部分偏离正常发育规律和轨迹,从而导致各系统、各部分之间不协调,整体失衡的现象。以体格发育和行为发育为例,约有5%~6%的儿童存在发育协调障碍,表现为运动技能发育迟缓或协调运动困难,这些儿童在运动时动作笨拙、不协调,难以完成日常任务 3,可导致读写困难、社交能力下降、产生抑郁自卑心理等问题 4 , 5,对于家庭生活质量和父母心理健康也会造成负面影响 6。以儿童青少年身高生长和体重增长为例,当体重增加超过身高生长轨迹时,就会引起生长不平衡,表现为体脂增加过多,进而成为成年期血脂水平异常的诱因 7
健康和疾病的发育起源(developmental origins of health and disease,DOHaD)学说指出,宫内营养不良的环境会迫使胎儿做出“预知适应性反应”,提前调整机体的组织结构和生理代谢功能,以适应出生后乃至成年的生存环境,如出生后真实环境与适应性反应不符,就会影响机体代谢功能和健康 8 , 9 , 10。同理,在生长发育时期,如果出现外部环境与内在生长发育速度不匹配,也会使得生长发育出现不平衡的情况,成为儿童青少年许多重要共病的原因之一。
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备注信息
A
马军,Email: nc.defudabe.umjbtnujam
B
宋逸, 马军. 纠正生长发育不平衡 预防儿童青少年重要共病[J]. 中华预防医学杂志, 2023, 57(4): 451-456. DOI: 10.3760/cma.j.cn112150-20221006-00962.
C
所有作者声明无利益冲突
D
首都卫生发展科研专项 (2022-1G-4251)
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