[综述]
中心性浆液性脉络膜视网膜病变(CSC)是当今影响青壮年人群视力的主要疾病，因发病率较高且易复发的特点使得其治疗较为棘手。目前临床上常用的CSC治疗方法包括光动力疗法、传统激光光凝治疗、阈值下微脉冲激光光凝(SDM)治疗、抗血管内皮生长因子治疗等，其中SDM是一种高频率、短促、阈值下、选择性光凝的激光，因为其能量小，安全性好、创伤小等优点受到了众多临床医生的青睐。不同波长的激光可被眼内不同色素吸收，因此不同CSC的发病部位所选用的SDM发射的治疗光波长也不尽相同。SDM治疗需要确定有效的治疗范围和参数，避免治疗不足或治疗过度。本文就SDM治疗CSC的机制、不同波长阈值下微脉冲激光的区别、治疗部位及参数选择、有效性及安全性进行了综述并对其未来的治疗前景进行展望。
Central serous chorioretinopathy (CSC) is a primary disease that affects the vision of young and middle-aged people.Its treatment is difficult because of its high incidence and easy recurrence.Currently, the commonly used clinical treatment methods for CSC include photodynamic therapy, traditional laser photocoagulation, subthreshold micropulse laser photocoagulation (SDM), anti-vascular endothelial growth factor therapy, and so on.SDM is a high-frequency, short, subthreshold and selective laser, which is preferred by many clinicians because of its low energy, good safety, small trauma and so on.Different wavelengths of laser can be absorbed by different pigments in the eye, so the therapeutic wavelengths of SDM for different sites of CSC are also different.In SDM treatment, it is necessary to determine the effective treatment range and parameters to avoid undertreatment or overtreatment.In this article, the mechanism of SDM in the treatment of CSC, the difference of SDM under different wavelengths, the selection of treatment site and parameters, the efficacy and safety were reviewed, and the prospect of SDM in the future was envisioned.
乔芯蕊,安建斌. 阈值下微脉冲激光光凝治疗中心性浆液性脉络膜视网膜病变的研究现状和展望[J]. 中华实验眼科杂志,2023,41(07)：688-692.
DOI:10.3760/cma.j.cn115989-20200506-00309版权归中华医学会所有。
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