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ENGLISH ABSTRACT
早发性卵巢功能不全的临床诊疗专家共识（2023版）
中华医学会妇产科学分会绝经学组
作者及单位信息
·
DOI： 10.3760/cma.j.cn112141-20230316-00122
Consensus of clinical diagnosis and treatment of premature ovarian insufficiency (2023)
Menopause Subgroup, Chinese Society of Obstetrics and Gynecology, Chinese Medical Association
Authors Info & Affiliations
Menopause Subgroup, Chinese Society of Obstetrics and Gynecology, Chinese Medical Association
·
DOI： 10.3760/cma.j.cn112141-20230316-00122
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摘要

早发性卵巢功能不全（POI）指女性在40岁之前出现的卵巢功能减退，发病率为1%~4%。不同于正常女性的自然绝经，POI不仅影响患者的生育力、心理健康及生命质量，而且对骨骼、心血管、泌尿生殖系统和认知等神经系统健康造成严重影响。POI的病因包括遗传、免疫、感染、环境及医源性因素等，但确切的发病机制尚不明确，迄今为止尚无确切有效的恢复卵巢功能的方法。因此，早期筛查、诊断和处理POI，有利于改善患者的生育结局、提高生命质量、减少长期健康问题及远期并发症。由中华医学会妇产科学分会绝经学组组织中国绝经专业领域的专家对国内外最新循证医学证据进行深入分析，结合我国的具体情况，制定了《早发性卵巢功能不全的临床诊疗专家共识（2023版）》，旨在为各级医师的临床实践提供指导。

引用本文

中华医学会妇产科学分会绝经学组. 早发性卵巢功能不全的临床诊疗专家共识（2023版）[J]. 中华妇产科杂志,2023,58(10)：721-728.

DOI:10.3760/cma.j.cn112141-20230316-00122

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早发性卵巢功能不全（premature ovarian insufficiency，POI）是指女性在40岁之前出现的卵巢功能减退，主要表现为月经异常（闭经、月经稀发）、卵泡刺激素（follicle stimulating hormone，FSH）>25 U/L、雌激素水平波动性下降［ 1 ］。POI的发病率为1%~4%［ 2 ］，全球性POI发病率的分析显示为3.7%［ 3 ］。根据是否曾有自发月经，分为原发性POI和继发性POI。
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备注信息
A
吴洁，南京医科大学第一附属医院妇产科，南京 210036，Email：mocdef.6ab21dmeijuw
B
郁琦，中国医学科学院北京协和医院妇产科，北京 100730，Email：mocdef.aabnis1008002iquy
C
中华医学会妇产科学分会绝经学组. 早发性卵巢功能不全的临床诊疗专家共识（2023版）[J]. 中华妇产科杂志, 2023, 58(10): 721-728. DOI: 10.3760/cma.j.cn112141-20230316-00122.
D
所有作者声明无利益冲突。参与本共识制定的所有成员申明无与本共识主题相关的任何商业、专业及其他方面的利益
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