高级检索
国际麻醉学与复苏杂志
期刊首页
过刊列表
高级检索
稿件发表
• 综述·临床麻醉 •
ENGLISH ABSTRACT
术后疲劳综合征防治措施的研究进展
葛震坤
李娟
作者及单位信息
·
DOI： 10.3760/cma.j.cn321761-20230417-00910
Research progress on prevention and treatment of postoperative fatigue syndrome
Ge Zhenkun
Li Juan
Authors Info & Affiliations
Ge Zhenkun
Graduate School of Wannan Medical College, Wuhu 241001, China
Department of Anesthesiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China
Li Juan
Department of Anesthesiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China
·
DOI： 10.3760/cma.j.cn321761-20230417-00910
961
150
0
0
4
3
PDF下载
APP内阅读
摘要

术后疲劳综合征（postoperative fatigue syndrome, POFS）是大中型外科手术后常见的并发症，可能与手术创伤、术后疼痛、睡眠质量、营养支持和精神状态有关，是妨碍患者术后康复的重要原因之一。随着快速康复理念在围手术期普及，POFS的防治越来越受到重视。文章通过对POFS的发病率、评估方法、可能的发病机制及防治措施等进行综述分析，为临床促进患者术后快速康复提供参考。

术后疲劳综合征;麻醉;术后康复
ABSTRACT

Postoperative fatigue syndrome (POFS) is a common complication after medium and large surgical operations, which may be related to surgical trauma, postoperative pain, sleep quality, nutritional support, and mental state, and is one of the important reasons hindering postoperative rehabilitation of patients. With the popularization of the concept of enhanced recovery after surgery in the perioperative period, POFS has attracted more and more attention. This article reviews and analyzes the incidence, evaluation methods, possible pathogenesis, and prevention measures of POFS, and the aim is to provide a reference for the clinical promotion of rapid recovery after surgery.

Postoperative fatigue syndrome;Anaesthesia;Postoperative recovery
Li Juan, Email: mocdef.6ab219991izumauh
Copyright by Chinese Medical Association
No content published by the journals of Chinese Medical Association may be reproduced or abridged without authorization. Please do not use or copy the layout and design of the journals without permission.
All articles published represent the opinions of the authors, and do not reflect the official policy of the Chinese Medical Association or the Editorial Board, unless this is clearly specified.
引用本文

葛震坤,李娟. 术后疲劳综合征防治措施的研究进展[J]. 国际麻醉学与复苏杂志,2023,44(10)：1105-1110.

DOI:10.3760/cma.j.cn321761-20230417-00910

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价

版权归中华医学会所有。

未经授权，不得转载、摘编本刊文章，不得使用本刊的版式设计。

除非特别声明，本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

术后疲劳综合征（postoperative fatigue syndrome, POFS）发生于患者手术后的恢复期，主要表现为程度不一的心不在焉、机体乏力、主观能动性不足等，临床症状常为疲惫不堪、力困筋乏、身体伤痛、体力不支、胃肠功能紊乱和睡眠反常等 [ 1 ]。POFS延缓患者术后康复，延长住院时间，严重影响患者术后心理健康和生活质量，降低满意度 [ 2 ]。随着加速康复外科在临床中的广泛应用，POFS防治越来越受到重视。本文将从POFS的发病率、评估方法、发病机制及防治措施等方面进行综述，为临床防治POFS提供依据。
参考文献
[1]
Christensen T , Kehlet H . Postoperative fatigue[J]. World J Surg, 1993,17(2):220-225. DOI: 10.1007/BF01658930 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Mendy N , Moriceau J , Sacuto Y ,et al. Postoperative fatigue after day surgery: prevalence and risk factors. A prospective observational study[J]. Minerva Anestesiol, 2020,86(12):1269-1276. DOI: 10.23736/S0375-9393.20.14358-X .
返回引文位置Google Scholar
百度学术
万方数据
[3]
Oliveira M , Oliveira G , Souza-Talarico J ,et al. Surgical oncology: evolution of postoperative fatigue and factors related to its severity[J]. Clin J Oncol Nurs, 2016,20(1):E3-E8. DOI: 10.1188/16.CJON.E3-E8 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
Christensen T , Bendix T , Kehlet H . Fatigue and cardiorespiratory function following abdominal surgery[J]. Br J Surg, 1982,69(7):417-419. DOI: 10.1002/bjs.1800690721 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
Mohamed NE , Shah QN , Kata HE ,et al. Dealing with the unthinkable: bladder and colorectal cancer patients ' and informal caregivers ' unmet needs and challenges in life after ostomies [J]. Semin Oncol Nurs, 2021,37(1):151111. DOI: 10.1016/j.soncn.2020.151111 .
返回引文位置Google Scholar
百度学术
万方数据
[6]
Crane PB , Efird JT , Abel WM . Fatigue in older adults postmyocardial infarction[J]. Front Public Health, 2016,4:55. DOI: 10.3389/fpubh.2016.00055 .
返回引文位置Google Scholar
百度学术
万方数据
[7]
Verschuur EM , Steyerberg EW , Kuipers EJ ,et al. Experiences and expectations of patients after oesophageal cancer surgery: an explorative study[J]. Eur J Cancer Care (Engl), 2006,15(4):324-332. DOI: 10.1111/j.1365-2354.2006.00659.x .
返回引文位置Google Scholar
百度学术
万方数据
[8]
Winters-Stone KM , Bennett JA , Nail L ,et al. Strength, physical activity, and age predict fatigue in older breast cancer survivors[J]. Oncol Nurs Forum, 2008,35(5):815-821. DOI: 10.1188/08.ONF.815-821 .
返回引文位置Google Scholar
百度学术
万方数据
[9]
Wirken L , van Middendorp H , Hooghof CW ,et al. The course and predictors of health-related quality of life in living kidney donors: a systematic review and meta-analysis[J]. Am J Transplant, 2015,15(12):3041-3054. DOI: 10.1111/ajt.13453 .
返回引文位置Google Scholar
百度学术
万方数据
[10]
Dew MA , Myaskovsky L , Steel JL ,et al. Managing the psychosocial and financial consequences of living donation[J]. Curr Transplant Rep, 2014,1(1):24-34. DOI: 10.1007/s40472-013-0003-4 .
返回引文位置Google Scholar
百度学术
万方数据
[11]
Zargar-Shoshtari K , Hill AG . Postoperative fatigue: a review[J]. World J Surg, 2009,33(4):738-745. DOI: 10.1007/s00268-008-9906-0 .
返回引文位置Google Scholar
百度学术
万方数据
[12]
Paddison JS , Booth RJ , Hill AG ,et al. Comprehensive assessment of peri-operative fatigue: development of the Identity-Consequence Fatigue Scale[J]. J Psychosom Res, 2006,60(6):615-622. DOI: 10.1016/j.jpsychores.2005.08.008 .
返回引文位置Google Scholar
百度学术
万方数据
[13]
Nøstdahl T , Bernklev T , Raeder J ,et al. Postoperative fatigue; translation and validation of a revised 10-item short form of the Identity-Consequence Fatigue Scale (ICFS)[J]. J Psychosom Res, 2016,84:1-7. DOI: 10.1016/j.jpsychores.2016.03.002 .
返回引文位置Google Scholar
百度学术
万方数据
[14]
Paddison JS , Sammour T , Kahokehr A ,et al. Development and validation of the Surgical Recovery Scale (SRS)[J]. J Surg Res, 2011,167(2):e85-e91. DOI: 10.1016/j.jss.2010.12.043 .
返回引文位置Google Scholar
百度学术
万方数据
[15]
Sammour T , Kahokehr A , Chan S ,et al. The humoral response after laparoscopic versus open colorectal surgery: a meta-analysis[J]. J Surg Res, 2010,164(1):28-37. DOI: 10.1016/j.jss.2010.05.046 .
返回引文位置Google Scholar
百度学术
万方数据
[16]
董千铜,章晓东,余震,等. 胃癌患者术后疲劳综合征的中西医结合治疗研究[J]. 中国中西医结合杂志, 2010,30(10):1036-1040.
返回引文位置Google Scholar
百度学术
万方数据
[17]
裘益辉,虞冠锋,叶星照,等. 脑5-羟色胺及其旁路关键酶在术后疲劳综合征大鼠模型中的变化[J]. 温州医科大学学报, 2015, (2):85-88;85-88, 94. DOI: 10.3969/j.issn.2095-9400.2015.02.002 .
返回引文位置Google Scholar
百度学术
万方数据
[18]
陈万,田诗彬,吴春燕. 中枢疲劳恢复期大鼠海马GDNF、GFRα-1mRNA及其蛋白表达的动态变化特征[J]. 山东体育学院学报, 2015,31(2):68-73. DOI: 10.3969/j.issn.1006-2076.2015.02.014 .
返回引文位置Google Scholar
百度学术
万方数据
[19]
Chen WZ , Liu S , Chen FF , et al . Prevention of postoperative fatigue syndrome in rat model by ginsenoside Rb1 via down-regulation of inflammation along the NMDA receptor pathway in the hippocampus[J]. Biol Pharm Bull, 2015,38(2):239-247. DOI: 10.1248/bpb.b14-00599 .
返回引文位置Google Scholar
百度学术
万方数据
[20]
Liu S , Cheng Y , Chen WZ ,et al. Inflammation disturbed the tryptophan catabolites in hippocampus of post-operative fatigue syndrome rats via indoleamine 2,3-dioxygenas enzyme and the improvement effect of ginsenoside Rb1[J]. Front Neurosci, 2021,15:652817. DOI: 10.3389/fnins.2021.652817 .
返回引文位置Google Scholar
百度学术
万方数据
[21]
Zhuang CL , Mao XY , Liu S ,et al. Ginsenoside Rb1 improves postoperative fatigue syn drome by reducing skeletal muscle oxidative stress through activation of the PI3K/Akt/Nrf2 pathway in aged rats [J]. Eur J Pharmacol, 2014,740:480-487. DOI: 10.1016/j.ejphar.2014.06.040 .
返回引文位置Google Scholar
百度学术
万方数据
[22]
毛翔宇,庄成乐,陈伟哲,等. 人参皂苷Rb1激活Nrf2/ARE通路对术后疲劳综合征老年大鼠骨骼肌氧化应激损伤的影响[J]. 医学研究杂志, 2014,43(5):26-30.
返回引文位置Google Scholar
百度学术
万方数据
[23]
Yang QY , Lai XD , Ouyang J ,et al. Effects of ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats[J]. Toxicology, 2018,409:144-151. DOI: 10.1016/j.tox.2018.08.010 .
返回引文位置Google Scholar
百度学术
万方数据
[24]
Yu J , Zhuang CL , Shao SJ ,et al. Risk factors for postoperative fatigue after gastrointestinal surgery[J]. J Surg Res, 2015,194(1):114-119. DOI: 10.1016/j.jss.2014.09.041 .
返回引文位置Google Scholar
百度学术
万方数据
[25]
余欣梅. 不同手术方式对宫颈癌根治术后疲劳综合征和免疫功能的影响[J]. 国际妇产科学杂志, 2017,44(5):512-515. DOI: 10.3969/j.issn.1674-1870.2017.05.007 .
返回引文位置Google Scholar
百度学术
万方数据
[26]
张利普,马红霞. 个体化心理干预对胃癌术后疲劳综合征的影响[J]. 世界最新医学信息文摘（连续型电子期刊）, 2019,19(85):83-84. DOI: 10.19613/j.cnki.1671-3141.2019.85.050 .
返回引文位置Google Scholar
百度学术
万方数据
[27]
唐楠,钟梦诗,李晓波. 积极心理品质对急性心肌梗死介入术后患者疲劳的影响[J]. 护理学杂志, 2017,32(23):85-87. DOI: 10.3870/j.issn.1001-4152.2017.23.085 .
返回引文位置Google Scholar
百度学术
万方数据
[28]
罗湘玉,张军,郭家龙. 食管癌术后实施同理心护理干预对患者心理及疲劳综合征的影响[J]. 长春中医药大学学报, 2016,32(5):988-991. DOI: 10.13463/j.cnki.cczyy.2016.05.038 .
返回引文位置Google Scholar
百度学术
万方数据
[29]
王坤,陈长英,艾建赛,等. 正念减压疗法对乳腺癌患者化疗期间疲乏及睡眠质量的影响[J]. 中华护理杂志, 2017,52(5):518-523. DOI: 10.3761/j.issn.0254-1769.2017.05.001 .
返回引文位置Google Scholar
百度学术
万方数据
[30]
任博博,巩玉亮. 磷酸肌酸钠对胃癌根治术后疲劳综合征患者炎症反应及营养状态的影响[J]. 海南医学, 2020,31(21):2758-2760. DOI: 10.3969/j.issn.1003-6350.2020.21.011 .
返回引文位置Google Scholar
百度学术
万方数据
[31]
章晓东,余震,姚建高,等. 肠内营养联合人参皂甙Rb1对术后疲劳综合征大鼠模型的影响[J]. 中华临床营养杂志, 2010,18(1):38-41. DOI: 10.3760/cma.j.issn.1674-635X.2010.01.010 .
返回引文位置Google Scholar
百度学术
万方数据
[32]
Machado P , Pimenta S , Oliveiros B ,et al. Effect of exercise training on quality of life after colorectal and lung cancer surgery: a meta-analysis[J]. Cancers (Basel), 2021,13(19):4975. DOI: 10.3390/cancers13194975 .
返回引文位置Google Scholar
百度学术
万方数据
[33]
Baumann FT , Zopf EM , Bloch W . Clinical exercise interventions in prostate cancer patients--a systematic review of randomized controlled trials[J]. Support Care Cancer, 2012,20(2):221-233. DOI: 10.1007/s00520-011-1271-0 .
返回引文位置Google Scholar
百度学术
万方数据
[34]
张立,黄艳娇,郑红梅. 心肺康复训练在改善高龄食管癌患者术后疲劳综合征中的应用[J]. 湖北医药学院学报, 2022,41(5):518-520. DOI: 10.13819/j.issn.2096-708X.2022.05.020 .
返回引文位置Google Scholar
百度学术
万方数据
[35]
王鹏浩,孟宪慧. 经皮穴位电刺激通过抑制炎性反应缓解老年患者肺癌根治术后疲劳综合征[J]. 国际医药卫生导报, 2021,27(10):1428-1432. DOI: 10.3760/cma.j.issn.1007-1245.2021.10.002 .
返回引文位置Google Scholar
百度学术
万方数据
[36]
杨泽填. 艾灸改善大肠癌术后疲劳综合征的临床研究[D]. 广州:广州中医药大学, 2019:12-24.
返回引文位置Google Scholar
百度学术
万方数据
[37]
王丽芬,姜岚. 耳穴贴压联合情志护理治疗老年患者髋部骨折术后疲劳综合征的临床疗效观察[J]. 中医临床研究, 2021,13(27):66-68;66-68, 94. DOI: 10.3969/j.issn.1674-7860.2021.27.024 .
返回引文位置Google Scholar
百度学术
万方数据
[38]
Bartlett EL , Zavlin D , Friedman JD ,et al. Enhanced recovery after surgery: the plastic surgery paradigm shift[J]. Aesthet Surg J, 2018,38(6):676-685. DOI: 10.1093/asj/sjx217 .
返回引文位置Google Scholar
百度学术
万方数据
[39]
王丽卉,刘昕,董玉颖,等. 不同阿片类镇痛药对无痛胃镜检查术后疲劳综合征的影响[J]. 国际麻醉学与复苏杂志, 2022,43(4):341-344. DOI: 10.3760/cma.j.cn321761-20210923-00515 .
返回引文位置Google Scholar
百度学术
万方数据
[40]
周冬娜,肖旺频,周红梅,等. 超声引导改良胸腰筋膜间平面阻滞对腰椎融合术老年患者术后疲劳综合征的影响[J]. 中华实验外科杂志, 2021,38(12):2527-2530. DOI: 10.3760/cma.j.cn421213-20210415-01124 .
返回引文位置Google Scholar
百度学术
万方数据
[41]
隆巧玉,葛亚丽,腾永杰,等. BIS指导下全麻对腔镜胃肠肿瘤切除术老年患者术后疲劳综合征的影响[J]. 中华麻醉学杂志, 2022,42(4):394-398. DOI: 10.3760/cma.j.cn131073.20220102.00403 .
返回引文位置Google Scholar
百度学术
万方数据
[42]
Yang X , Wu Q , Wang H ,et al. Effects of ultrasound-guided stellate ganglion block on postoperative quality of recovery in patients undergoing breast cancer surgery: a randomized controlled clinical trial[J]. J Healthc Eng, 2022,2022:7628183. DOI: 10.1155/2022/7628183 .
返回引文位置Google Scholar
百度学术
万方数据
[43]
董军久,易斌,鲁开智. 低剂量氯胺酮配合右美托咪定对宫颈癌根治术病人术后疲劳程度及疼痛介质、免疫功能状态的影响[J]. 蚌埠医学院学报, 2022,47(4):456-461. DOI: 10.13898/j.cnki.issn.1000-2200.2022.04.008 .
返回引文位置Google Scholar
百度学术
万方数据
备注信息
A
李娟，Email： mocdef.6ab219991izumauh
B
所有作者声明无利益冲突
C
中央高校基本科研业务费专项资金资助 (YD9110002015)
评论 （0条）
注册
登录
时间排序
暂无评论，发表第一条评论抢沙发
最新推荐
更多
帕金森病患者情感淡漠评估工具的研究进展
肖梦伟 等
中华现代护理杂志 2025,31(01)
快眼动睡眠行为障碍与早期帕金森病患者运动及非运动症状特征
刘柳 等
中华行为医学与脑科学杂志 2022,31(07)
伴情感淡漠的帕金森病患者前瞻性记忆研究
杨静 等
中华神经医学杂志 2018,17(04)
早期帕金森病患者非运动症状的临床表现
李振光 等
中华神经科杂志 2015,48(08)
MedAI助手（体验版）
文档即答
智问智答
机器翻译
回答内容由人工智能生成，我社无法保证其准确性和完整性，该生成内容不代表我们的态度或观点，仅供参考。
生成快照
文献快照

你好，我可以帮助您更好的了解本文，请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持：

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号
小中大