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炎症细胞在慢性鼻-鼻窦炎伴鼻息肉中的研究进展
陈杨
刘建敏
作者及单位信息
·
DOI： 10.3760/cma.j.issn.1673-4106.2023.05.008
Research progress of inflammatory cells in chronic rhinosinusitis with nasal polyps
Chen Yang
Liu Jianmin
Authors Info & Affiliations
Chen Yang
Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of the WesternTheater Command of the Chinese People's Liberation Army, Chengdu 610036, China
Liu Jianmin
Department of Otorhinolaryngology Head and Neck Surgery, Deyang City People's Hospital, Deyang 618000, China
·
DOI： 10.3760/cma.j.issn.1673-4106.2023.05.008
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摘要

慢性鼻-鼻窦炎伴鼻息肉是耳鼻咽喉头颈外科常见病，其发病机制尚不明确，主要是多种炎症细胞刺激下鼻黏膜发生的慢性持续性炎症。但因其病程长，手术复发率高，严重影响患者的生活质量。近年来，随着对该病发病机制研究的不断深入，将有助于我们寻找新的治疗靶点。本文就慢性鼻-鼻窦炎伴鼻息肉的炎症细胞研究现状做一综述，旨在为临床指导个体化治疗方案提供参考。

鼻窦炎;鼻息肉;炎症细胞
引用本文

陈杨,刘建敏. 炎症细胞在慢性鼻-鼻窦炎伴鼻息肉中的研究进展[J]. 国际耳鼻咽喉头颈外科杂志,2023,47(05)：285-289.

DOI:10.3760/cma.j.issn.1673-4106.2023.05.008

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慢性鼻-鼻窦炎伴鼻息肉（chronic rhinosinusitis with nasal polyps，CRSwNP）是慢性鼻窦炎的一种亚型，最常见的临床症状为鼻塞（97%）和嗅觉减退（90%） [ 1 ]，睡眠障碍及流涕次之。CRSwNP发病机制十分复杂且具有高度异质性，导致患者经常规治疗预后不佳、治疗方案不足等问题，研究表明针对CRSwNP的治疗需根据患者的炎症表型制定个体化方案。本文针对CRSwNP的治疗组织中不同类型的炎症细胞表达情况以及细胞间相互作用做一综述，期待深入了解鼻息肉的炎症特征，为探索其发病机制和个体化治疗提供新思路。
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刘建敏，Email： mocdef.3ab61ylnimnaijuil
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四川省医学会课题 (Q18007)
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