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ENGLISH ABSTRACT
放射治疗引起动脉狭窄的研究进展
丁江燚
倪昕晔
作者及单位信息
·
DOI： 10.3760/cma.j.cn112271-20230418-00124
Advances in research on artery stenosis induced by radiation therapy
Ding Jiangyi
Ni Xinye
Authors Info & Affiliations
Ding Jiangyi
Department of Radiation Oncology, Changzhou No. 2 People′s Hospital Affiliated to Nanjing Medical University, Center of Medical Physics, Nanjing Medical University, Jiangsu Province Engineering Research Center of Medical Physics, Changzhou 213003, China
Ni Xinye
Department of Radiation Oncology, Changzhou No. 2 People′s Hospital Affiliated to Nanjing Medical University, Center of Medical Physics, Nanjing Medical University, Jiangsu Province Engineering Research Center of Medical Physics, Changzhou 213003, China
·
DOI： 10.3760/cma.j.cn112271-20230418-00124
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摘要

作为当下癌症治疗的一个重要组成部分，放射治疗带来治疗效果的同时，也伴随着慢性并发症的风险，这引起了人们的高度关注。患者接受放疗后，随着年限的增加，颈部和心脏周边血管疾病的发病率增高，其中一项主要原因就是放射线导致血管损伤引起的动脉狭窄病变。为了更深入地了解动脉狭窄，对其危险因素、临床表现、发病机制、预防建议及治疗方法作一综述。

放射治疗;慢性并发症;心血管疾病;血管损伤;动脉狭窄
ABSTRACT

Radiation therapy (RT), as a crucial part of current cancer treatment, has caused great concern since it brings therapeutic efficacy along with the risk of chronic complications. With an increase in age, patients treated with RT are subjected to a high incidence of vascular diseases in the neck and peripheral heart primarily due to the artery stenosis induced by radiation-caused vascular injury. To gain a deeper understanding of artery stenosis, its hazards, clinical presentation, pathogenesis, preventive recommendations, and treatment method was reviewed.

Radiation therapy;Chronic complications;Cardiovascular disease;Vascular injury;Artery stenosis
Ni Xinye, Email: mocdef.nabuyila0002yxn
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引用本文

丁江燚,倪昕晔. 放射治疗引起动脉狭窄的研究进展[J]. 中华放射医学与防护杂志,2023,43(12)：1041-1048.

DOI:10.3760/cma.j.cn112271-20230418-00124

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癌症病发率逐年上升，放射治疗(radiation therapy，RT)是治疗多种肿瘤的重要手段，通过大量临床实例，发现放疗会对组织、血管及器官等造成一定的损伤。因为在照射肿瘤的同时，照射范围附近的血管或器官也会受到照射影响 [ 1 , 2 ]。例如在胸段放疗(乳腺癌、肺癌等)时，心脏的部分边缘会涵盖在照射范围内，因此增加了心血管疾病(cardiovascular，CV，冠脉狭窄、心肌梗死、瓣膜性心脏病、心包炎等)发生的风险 [ 3 ]。
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备注信息
A
倪昕晔，Email: mocdef.nabuyila0002yxn
B

丁江燚负责文献阅读和论文撰写；倪昕晔指导论文修改

C
丁江燚，倪昕晔．放射治疗引起动脉狭窄的研究进展[J]．中华放射医学与防护杂志，2023, 43(12): 1041-1048.DOI：10.3760/cma.j.cn112271-20230418-00124.
D
Ding JY, Ni XY. Advances in research on artery stenosis induced by radiation therapy[J]．Chin J Radiol Med Prot，2023, 43(12): 1041-1048. DOI：10.3760/cma.j.cn112271-20230418-00124.
E
所有研究者未因该研究而接受任何不正当的职务或财务利益，在此对研究的独立性核科学性予以保障
F
国家自然科学基金 (62371243)
江苏省重点研发计划社会发展项目 (BE2022720)
江苏省卫健委面上项目 (M2020006)
江苏省医学重点学科建设单位（肿瘤治疗学-放射治疗） (JSDW202237)
江苏省自然科学基金 (BK20231190)
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