高级检索
数字医学与健康
期刊首页
过刊列表
高级检索
稿件发表
• 综述 •
ENGLISH ABSTRACT
区块链技术在数字医疗与健康中的应用进展
苏娜
葛乐昕
范雯
袁松涛
作者及单位信息
·
DOI： 10.3760/cma.j.cn101909-20230817-00022
Progress in the application of blockchain technology in digital medicine and health
Su Na
Ge Lexin
Fan Wen
Yuan Songtao
Authors Info & Affiliations
Su Na
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Ge Lexin
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Fan Wen
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Yuan Songtao
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
·
DOI： 10.3760/cma.j.cn101909-20230817-00022
2118
114
0
0
1
0
PDF下载
APP内阅读
摘要

区块链是一种去中心化、不可篡改、可以追溯、公开透明、安全可信、集体维护、分布式的数据库技术，广泛地用于商业、金融、医学等各个领域。在医学领域，各个利益相关者正在积极探索区块链，以降低成本、优化业务流程、提高合规性并更好地利用医疗相关数据改善患者健康状况。本文综述了区块链在医疗卫生领域的应用与潜在发展，包括医疗信息的存储与共享，辅助医疗供应链与可追溯管理，辅助医疗物联网、临床应用与医学研究，集合人工智能（AI）与大数据，辅助传染病的防治与管理。使用大数据作为平台，辅以AI相关技术，鼓励医生、护士，以及生物技术和其他医疗机构参与进来，为支持、优化、加速和促进医疗健康提供手段。

区块链;医疗应用;临床实践;人工智能
ABSTRACT

Blockchain is a collectively maintained and distributed database technology that is decentralized, immutable, traceable, open, transparent, secure, and trusted. It is widely used in business, finance, medicine and other fields. In the healthcare system, stakeholders are exploring blockchain technology to reduce costs, optimize processes, improve compliance, and leverage medical data to enhance patient health. This paper examines the potential use and development of blockchain technology in healthcare, including storage and sharing of medical information, auxiliary medical supply chain and traceability management, auxiliary medical Internet of Things, clinical applications and medical research, integrated artificial intelligence and big data, and auxiliary prevention and management of COVID-19 and other infectious diseases. In the future, big data supplemented by AI technologies could be used as a platform to engage healthcare professionals and organizations, such as doctors, nurses, and biotechnology companies, to support, optimize, accelerate, and promote healthcare systems.

Blockchain;Medical applications;Clinical practice;Artificial intelligence
Yuan Songtao, Email: nc.defudabe.umjnnauyoatgnos
Copyright by Chinese Medical Association
No content published by the journals of Chinese Medical Association may be reproduced or abridged without authorization. Please do not use or copy the layout and design of the journals without permission.
All articles published represent the opinions of the authors, and do not reflect the official policy of the Chinese Medical Association or the Editorial Board, unless this is clearly specified.
引用本文

苏娜,葛乐昕,范雯,等. 区块链技术在数字医疗与健康中的应用进展[J]. 数字医学与健康,2024,02(02)：119-123.

DOI:10.3760/cma.j.cn101909-20230817-00022

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价

版权归中华医学会所有。

未经授权，不得转载、摘编本刊文章，不得使用本刊的版式设计。

除非特别声明，本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

近年来，人工智能（artificial intelligence，AI）、区块链等现代技术被广泛提出并越来越多地应用于医疗健康领域。其中，人工智能通过深度学习能力在疾病筛查、诊疗、预测方面达到甚至超过人类水平而被广泛接受 ［ 1 ］ ，区块链因其去中心化、安全可信、集体维护、不可篡改等特点在医疗领域独具优势，但其在医疗中的应用尚处于初级阶段。目前国际上“区块链+医疗”的研究主要集中在计算机科学、工程学、医疗信息学、医疗保健和科学服务等领域，大多仅在技术阶段介绍了区块链平台的技术性能和设计，仅2.2%的研究显示了其临床应用 ［ 2 ］ 。
就诊信息的电子化转变使得医疗保健方案发生了巨大的变化。然而，数据的存储和在不同机构甚至不同学科之间的共享可能导致数据丢失或患者隐私泄露。此外，医疗供应链、物联网（internet of things，IoT）、药物研发、医学研究、治疗效果以及AI辅助医学大数据研究等方面缺乏透明性和公正性，特别是在突发传染病的监督和管理方面，这些问题突显了将区块链技术转化为临床用途的必要性。本文通过文献综述，从临床角度出发，讨论区块链在医疗领域中的潜在应用及如何更好地将区块链与AI技术相结合，提高医疗健康水平。
试读结束，您可以通过登录机构账户或个人账户后获取全文阅读权限。
参考文献
[1]
Ali S ,Abdullah, Armand T ,et al. Metaverse in healthcare integrated with explainable AI and blockchain: enabling immersiveness, ensuring trust, and providing patient data security[J]. Sensors (Basel), 2023,23(2):565. DOI: 10.3390/s23020565 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Ng WY , Tan TE , Movva P ,et al. Blockchain applications in health care for COVID-19 and beyond: a systematic review[J]. Lancet Digit Health, 2021,3(12):e819-e829. DOI: 10.1016/S2589-7500(21)00210-7 .
返回引文位置Google Scholar
百度学术
万方数据
[3]
Abu-Elezz I , Hassan A , Nazeemudeen A ,et al. The benefits and threats of blockchain technology in healthcare: A scoping review[J]. Int J Med Inform, 2020,142:104246. DOI: 10.1016/j.ijmedinf.2020.104246 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
Ng WY , Tan TE , Xiao Z ,et al. Blockchain technology for ophthalmology: coming of age?[J]. Asia Pac J Ophthalmol (Phila), 2021,10(4):343-347. DOI: 10.1097/APO.0000000000000399 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
魏明月,王淑,许德俊. 基于区块链的互联网医院患者电子病历安全共享模式与实践[J]. 医学信息学杂志, 2023,44(7):68-72. DOI: 10.3969/j.issn.1673-6036.2023.07.011 .
返回引文位置Google Scholar
百度学术
万方数据
Wei MY , Wang S , Xu DJ . Practice of the secure sharing mode of patient electronic medical records in internet hospitals based on blockchain[J]. Journal of Medical Informatics, 2023,44(7):68-72. DOI: 10.3969/j.issn.1673-6036.2023.07.011 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[6]
Ghayvat H , Pandya S , Bhattacharya P ,et al. CP-BDHCA: Blockchain-based confidentiality-privacy preserving big data scheme for healthcare clouds and applications[J]. IEEE J Biomed Health Inform, 2022,26(5):1937-1948. DOI: 10.1109/JBHI.2021.3097237 .
返回引文位置Google Scholar
百度学术
万方数据
[7]
张睿,李言飞,苏雪梅,等. 基于区块链和星际文件系统的电子健康档案存储和共享方案探讨[J/OL]. 疾病监测:1-6[2023-12-08]. http://kns.cnki.net/kcms/detail/11.2928.R.20230705.1544.004.html.
返回引文位置Google Scholar
百度学术
万方数据
Zhang R , Li YF , Su XM ,et al. Blockchain and interplanetary file system-based solution for storing and sharing electronic health records[J/OL]. Disease Surveillance:1-6[2023-12-08]. http://kns.cnki.net/kcms/detail/11.2928.R.20230705.1544.004.html.
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[8]
Lo YS , Yang CY , Chien HF ,et al. Blockchain-enabled iwellchain framework integration with the national medical referral system: development and usability study[J]. J Med Internet Res, 2019,21(12):e13563. DOI: 10.2196/13563 .
返回引文位置Google Scholar
百度学术
万方数据
[9]
Uddin M , Salah K , Jayaraman R ,et al. Blockchain for drug traceability: Architectures and open challenges[J]. Health Informatics J, 2021,27(2):14604582211011228. DOI: 10.1177/14604582211011228 .
返回引文位置Google Scholar
百度学术
万方数据
[10]
胡诗玮,李楠,徐利. 基于区块链技术和综合评价的医疗器械追溯系统研究[J]. 自动化与仪器仪表, 2023(3):269-274. DOI: 10.14016/j.cnki.1001-9227.2023.03.269 .
返回引文位置Google Scholar
百度学术
万方数据
Hu SW , Li N , Xu L ,et al. Research on medical device traceability system based on blockchain technology and comprehensive evaluation[J]. Automation and Instrumentation, 2023(3):269-274. DOI: 10.14016/j.cnki.1001-9227.2023.03.269 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[11]
Singh R , Dwivedi AD , Srivastava G . Internet of things based blockchain for temperature monitoring and counterfeit pharmaceutical prevention[J]. Sensors (Basel), 2020,20(14):3951. DOI: 10.3390/s20143951 .
返回引文位置Google Scholar
百度学术
万方数据
[12]
McBee MP , Wilcox C . Blockchain technology: principles and applications in medical imaging[J]. J Digit Imaging, 2020,33(3):726-734. DOI: 10.1007/s10278-019-00310-3 .
返回引文位置Google Scholar
百度学术
万方数据
[13]
Lakhan A , Mohammed MA , Nedoma J ,et al. Federated-learning based privacy preservation and fraud-enabled blockchain ioMT System for Healthcare[J]. IEEE J Biomed Health Inform, 2023,27(2):664-672. DOI: 10.1109/JBHI.2022.3165945 .
返回引文位置Google Scholar
百度学术
万方数据
[14]
李嘉豪,李冬梅,张晓梅. 基于区块链的轻量级物联网医疗数据访问控制方案[J/OL]. 重庆邮电大学学报(自然科学版):1-8[2023-12-08]. http://kns.cnki.net/kcms/detail/50.1181.N.20230530.1026.002.html.
返回引文位置Google Scholar
百度学术
万方数据
Li JH , Li DM , Zhang XM . Blockchain-based lightweight IoT medical data access control scheme[J/OL]. Journal of Chongqing University of Posts and Telecommunications (Natural Science Edition):1-8[2023-12-08]. http://kns.cnki.net/kcms/detail/50.1181.N.20230530.1026.002.html.
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[15]
Wong DR , Bhattacharya S , Butte AJ . Prototype of running clinical trials in an untrustworthy environment using blockchain[J]. Nat Commun, 2019,10(1):917. DOI: 10.1038/s41467-019-08874-y .
返回引文位置Google Scholar
百度学术
万方数据
[16]
云东源,陈文贲. 区块链在药物临床试验中的应用[J]. 眼科学报, 2021,36(1):46-49. DOI: 10.3978/j.issn.1000-4432.2021.01.20 .
返回引文位置Google Scholar
百度学术
万方数据
Yun DY , Chen WH . Application of blockchain technology in clinical drug trial[J]. Yan Ke Xue Bao, 2021,36(1):46-49. DOI: 10.3978/j.issn.1000-4432.2021.01.20 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[17]
Zhuang Y , Sheets LR , Shae Z ,et al. Applying Blockchain Technology to Enhance Clinical Trial Recruitment[J]. AMIA Annu Symp Proc, 2019,2019:1276-1285.
返回引文位置Google Scholar
百度学术
万方数据
[18]
Gong Y , Shi Q , Duan D ,et al. Research on application of intelligent tracing system for IVD reagents based on blockchain technology][J]. Chinese Journal of Medical Instrumentation, 2021,45(1):105-108. DOI: 10.3969/j.issn.1671-7104.2021.01.022 .
返回引文位置Google Scholar
百度学术
万方数据
[19]
Gürsoy G , Brannon CM , Gerstein M . Using ethereum blockchain to store and query pharmacogenomics data via smart contracts[J]. BMC Med Genomics, 2020,13(1):74. DOI: 10.1186/s12920-020-00732-x .
返回引文位置Google Scholar
百度学术
万方数据
[20]
Jin XL , Zhang M , Zhou ZY ,et al. Application of a blockchain platform to manage and secure personal genomic data: a case study of LifeCODE.ai in China[J]. J Med Internet Res, 2019,21(9):e13587. DOI: 10.2196/13587 .
返回引文位置Google Scholar
百度学术
万方数据
[21]
Nasir MU , Khan S , Mehmood S ,et al. IoMT-based osteosarcoma cancer detection in histopathology images using transfer learning empowered with blockchain, fog computing, and edge computing[J]. Sensors (Basel), 2022,22(14):5444. DOI: 10.3390/s22145444 .
返回引文位置Google Scholar
百度学术
万方数据
[22]
Rehman A , Abbas S , Khan MA ,et al. A secure healthcare 5.0 system based on blockchain technology entangled with federated learning technique[J]. Comput Biol Med, 2022,150:106019. DOI: 10.1016/j.compbiomed.2022.106019 .
返回引文位置Google Scholar
百度学术
万方数据
[23]
Kuo TT , Gabriel RA , Cidambi KR ,et al. Expectation propagation logistic regression on permissioned blockchain (explorerchain): decentralized online healthcare/genomics predictive model learning[J]. J Am Med Inform Assoc, 2020,27(5):747-756. DOI: 10.1093/jamia/ocaa023 .
返回引文位置Google Scholar
百度学术
万方数据
[24]
Tan TE , Anees A , Chen C ,et al. Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study[J]. Lancet Digit Health, 2021,3(5):e317-e329.
返回引文位置Google Scholar
百度学术
万方数据
[25]
Ahmad RW , Salah K , Jayaraman R ,et al. Blockchain and COVID-19 pandemic: applications and challenges[J]. Cluster Comput, 2023,26(4):2383-2408.
返回引文位置Google Scholar
百度学术
万方数据
[26]
Ahmed I , Chehri A , Jeon G . Artificial intelligence and blockchain enabled smart healthcare system for monitoring and detection of COVID-19 in biomedical images[J]. IEEE/ACM Trans Comput Biol Bioinform, 2023:1-10. DOI: 10.1109/TCBB.2023.3294333 .
返回引文位置Google Scholar
百度学术
万方数据
[27]
Alkhader W , Salah K , Sleptchenko A ,et al. Blockchain-based decentralized digital manufacturing and supply for COVID-19 medical devices and supplies[J]. IEEE Access, 2021,9:137923-137940. DOI: 10.1109/ACCESS.2021.3118085 .
返回引文位置Google Scholar
百度学术
万方数据
[28]
Samuel O , Omojo AB , Onuja AM ,et al. IoMT: a COVID-19 healthcare system driven by federated learning and blockchain[J]. IEEE J Biomed Health Inform, 2023,27(2):823-834. DOI: 10.1109/JBHI.2022.3143576 .
返回引文位置Google Scholar
百度学术
万方数据
[29]
Wu X , Chen J , Yun D ,et al. Effectiveness of an ophthalmic hospital-based virtual service during the COVID-19 pandemic[J]. Ophthalmology, 2021,128(6):942-945. DOI: 10.1016/j.ophtha.2020.10.012 .
返回引文位置Google Scholar
百度学术
万方数据
[30]
Egala BS , Pradhan AK , Badarla V ,et al. iBlock: an intelligent decentralised blockchain-based pandemic detection and assisting system[J]. J Signal Process Syst, 2022,94(6):595-608. DOI: 10.1007/s11265-021-01704-9 .
返回引文位置Google Scholar
百度学术
万方数据
[31]
Tagliafico AS , Campi C , Bianca B ,et al. Blockchain in radiology research and clinical practice: current trends and future directions[J]. Radiol Med, 2022,127(4):391-397. DOI: 10.1007/s11547-022-01460-1 .
返回引文位置Google Scholar
百度学术
万方数据
[32]
Yu Z , Liu Y , Zhu C . Application of propofol in oral and maxillofacial surgery anesthesia based on smart medical blockchain technology[J]. J Healthc Eng, 2021,2021:5529798. DOI: 10.1155/2021/5529798 .
返回引文位置Google Scholar
百度学术
万方数据
[33]
Farooq MS , Suhail M , Qureshi JN ,et al. Consortium framework using blockchain for asthma healthcare in pandemics[J]. Sensors (Basel), 2022,22(21):8582. DOI: 10.3390/s22218582 .
返回引文位置Google Scholar
百度学术
万方数据
[34]
桂玉然,周红艳,舒细记. 利用区块链技术强化慢性病患者信息管理探讨[J]. 医学信息学杂志, 2023,44(1):75-78. DOI: 10.3969/j.issn.1673-6036.2023.01.014 .
返回引文位置Google Scholar
百度学术
万方数据
Gui YR , Zhou HY , Shu XJ . Discussion on using blockchain technology to strengthen information management of chronic patients[J]. Journal of Medical Informatics, 2023,44(1):75-78. DOI: 10.3969/j.issn.1673-6036.2023.01.014 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[35]
Zhou L , Wang L , Sun Y . MIStore: a Blockchain-Based Medical Insurance Storage System[J]. Journal of Medical Systems, 2018,42(8):Article:149. DOI: 10.1007/s10916-018-0996-4 .
返回引文位置Google Scholar
百度学术
万方数据
备注信息
A
袁松涛，Email： nc.defudabe.umjnnauyoatgnos
B

苏娜、葛乐昕：文献综述，论文撰写；范雯、袁松涛：研究指导，论文修改

C
苏娜, 葛乐昕, 范雯, 等. 区块链技术在数字医疗与健康中的应用进展[J]. 数字医学与健康, 2024, 2(2): 119-123. DOI: 10.3760/cma.j.cn101909-20230817-00022.
D
所有作者声明无利益冲突
E
国家自然科学基金面上项目 (81870694)
江苏省科技厅重点研发计划 (BE2018131)
江苏省基础研究计划青年基金项目 (BK20220730)
评论 （0条）
注册
登录
时间排序
暂无评论，发表第一条评论抢沙发
最新推荐
更多
扩散MRI技术在颞叶癫痫中的应用进展
杨文蕊 等
磁共振成像 2024,15(01)
叙事医学在患者健康教育中的应用进展
柏李裕年 等
中华全科医师杂志 2023,22(03)
电子健康档案区块链应用前景及其挑战
田生湖 等
中华医院管理杂志 2022,38(05)
虚拟现实技术在健康管理中的应用进展
洪文静 等
中华健康管理学杂志 2021,15(05)
MedAI助手（体验版）
文档即答
智问智答
机器翻译
回答内容由人工智能生成，我社无法保证其准确性和完整性，该生成内容不代表我们的态度或观点，仅供参考。
生成快照
文献快照

你好，我可以帮助您更好的了解本文，请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持：

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号
小中大