[综述]
[综述]
特发性黄斑前膜(iERM)是一种因黄斑区及周边视网膜形成非血管性纤维膜，继而因纤维膜的牵拉导致黄斑的变形、皱褶等导致患眼视力下降及视物变形的眼底疾病。光学相干断层扫描血管成像(OCTA)凭借无创、分辨率高、可分层显示视网膜血管、量化视网膜血管密度和无灌注血管区大小等优势，已被广泛应用于包括iERM在内的黄斑疾病的诊断中。OCTA除了可以提供视网膜微血管结构、血流灌注的数字化信息，揭示iERM对微血管结构的牵拉作用，还可以在疾病的随访中用于监测血流灌注的改变。虽然目前OCTA尚不能完全替代眼底血管造影检查，但其已经为进一步了解iERM的发病机制、疾病进程及预后因素带来了更加丰富的信息。本文就OCTA在iERM中的应用研究进展作一综述，以期为OCTA在iERM中的应用提供更多启示。
Idiopathic macular epiretinal membrane (iERM) is a kind of fundus disease caused by fibrocellular proliferation over the internal limiting membrane (ILM) followed by deformation and wrinkling of the macula due to traction of the fibrous membranes, leading to vision loss and visual distortion in the affected eye.Optical coherence tomography angiography (OCTA) has been widely used in the diagnosis of macular diseases including iERM by virtue of non-invasive, high resolution and stratified display of superficial and deep retinal vessels and quantification of retinal vessel density and non-perfusion area.OCTA can provide information of retinal microvascular structure and blood perfusion under disease conditions, revealing the pulling effect of iERM on the microvascular structure, and it can also be used to evaluate changes in blood flow during the course of disease follow-up.After surgery, OCTA can also be used for follow-up monitoring of microvascular structure and blood flow to further predict vision.Although OCTA cannot completely replace fundus angiography, it has provided richer information about the pathogenesis, disease progression and prognostic factors of iERM.This article reviews the progress of research on the application of OCTA in iERM to provide more insight into the application of OCTA in iERM.
徐钊楷,毛剑波,沈丽君. 光学相干断层扫描血管成像在特发性黄斑前膜中的应用研究进展[J]. 中华实验眼科杂志,2024,42(05)：483-486.
DOI:10.3760/cma.j.cn115989-20200713-00493版权归中华医学会所有。
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