甲状腺眼病(TED)是与甲状腺疾病密切相关的致盲眼眶病,严重影响患者的视功能和生活质量。25%~50%的弥漫性毒性甲状腺肿患者会继发TED。活动性分期是TED的重要评估指标,对于临床病情评估、治疗方案制定、预后评估等十分关键,而临床活动性评分(CAS)是目前国内外应用广泛的分期方法。为了提升CAS评价的准确性和一致性,欧洲Graves眼病专家组在TED指南中推荐使用CAS评分图谱。然而,该图谱主要基于高加索人,鉴于中国人与高加索人眼眶的解剖学差异以及眼部特征的不同,需要综合现有指南中评分细则进一步完善CAS评分,从而规范其在中国TFD患者中的操作方法和判断标准,为疾病精准诊疗提供可靠依据。
Thyroid eye disease (TED) is an orbital disease closely associated with thyroid disorders, with 25%-50% of patients with diffuse toxic goiter (Graves Disease) developing secondary TED, which can lead to blindness and disability and significantly impair patients' visual function and quality of life.Activity staging is a crucial assessment index for TED and is essential for clinical evaluation, treatment planning, and prognosis.The Clinical Activity Score (CAS) is currently the most widely used method for this purpose both domestically and internationally.To improve the accuracy and consistency of CAS evaluations, the European Group of Graves' Orbitopathy (EUGOGO) recommended the use of a CAS scoring atlas in the TED guidelines.However, existing atlases are primarily based on Caucasians.Considering the anatomical differences in the orbit between Chinese and Caucasians and the resulting divergent ocular characteristics, there is a need for a comprehensive interpretation of the CAS scoring details in the current guidelines.This should be followed by further refinement to tailor the CAS scoring criteria to Chinese patients with TED.Such measures will standardize the operational methods and judgment criteria of CAS scoring in China, thereby providing a reliable basis for the accurate diagnosis and treatment of the disease.
雷超宇,王慧,孙静,等. 关注适合中国人群的甲状腺眼病临床活动性评分方法[J]. 中华实验眼科杂志,2024,42(11):977-982.
DOI:10.3760/cma.j.cn115989-20240418-00112版权归中华医学会所有。
未经授权,不得转载、摘编本刊文章,不得使用本刊的版式设计。
除非特别声明,本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

你好,我可以帮助您更好的了解本文,请向我提问您关注的问题。