临床研究
ENGLISH ABSTRACT
基于扩展现实的眼镜式可穿戴视觉训练系统在黄斑裂孔术后患者康复中的应用
袁静
王兴昌
孙锡全
焦辉广
王倩
俞建雄
涂碧玥
严茜茜
赵振
童艳霞
张书文
作者及单位信息
·
DOI: 10.3760/cma.j.cn115989-20240731-00217
Application of wearable visual training system based on extended reality glasses in patients after macular hole surgery
Yuan Jing
Wang Xingchang
Sun Xiquan
Jiao Huiguang
Wang Qian
Yu Jianxiong
Tu Biyue
Yan Xixi
Zhao Zhen
Tong Yanxia
Zhang Shuwen
Authors Info & Affiliations
Yuan Jing
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
Wang Xingchang
Shenzhen Vison Stick Medical Technology Co., Ltd., Shenzhen 518055, China
Sun Xiquan
Shenzhen Vison Stick Medical Technology Co., Ltd., Shenzhen 518055, China
Jiao Huiguang
Shenzhen Vison Stick Medical Technology Co., Ltd., Shenzhen 518055, China
Wang Qian
Shenzhen Vison Stick Medical Technology Co., Ltd., Shenzhen 518055, China
Yu Jianxiong
Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
Tu Biyue
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
Yan Xixi
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
Zhao Zhen
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
Tong Yanxia
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
Zhang Shuwen
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
·
DOI: 10.3760/cma.j.cn115989-20240731-00217
106
23
0
0
0
0
PDF下载
APP内阅读
摘要

目的评价基于扩展现实(XR)的眼镜式可穿戴视觉训练设备短期使用对黄斑裂孔术后患者的康复效果。

方法采用自身对照研究方法,于2022年10月至2024年3月在武汉大学人民医院眼科中心连续招募黄斑裂孔术后单眼低视力患者11例11眼作为研究对象。所有患者采用自主研发的视觉康复训练镜LOOKBON T10进行生物反馈训练3个月,比较训练前后LogMAR最佳矫正视力(BCVA)、视网膜敏感度、有效注视率、固视稳定性、阅读速度、视物垂直变形度(MV)和水平变形度(MH)及视觉相关生活质量评分量表(CVRQoL-25)评分。

结果患者训练后BCVA、视网膜敏感度、有效注视率、固视稳定率、阅读速度分别为0.69±0.19、(21.61±2.75)db、(92.43±4.06)%、(93.09±4.31)%和(104.82±21.85)个/min,较训练前的0.85±0.28、(17.71±3.17)db、(31.83±19.05)%、(32.35±19.12)%和(69.64±20.17)个/min明显改善,差异均有统计学意义( t=5.253、-5.987、-11.561、-12.003、-11.682,均 P<0.001)。训练后MV和MH分别为(0.29±0.20)°和(0.21±0.24)°,较训练前的(0.44±0.24)°和(0.43±0.41)°明显减轻,差异均有统计学意义( t=9.238、4.068,均 P<0.01)。训练后CVRQoL-25评分为(1 193.18±229.43)分,较训练前的(947.73±203.86)分显著提高,差异有统计学意义( t=-11.687, P<0.001)。

结论基于XR的眼镜式可穿戴视觉训练设备能有效改善黄斑裂孔术后视功能恢复不佳患者的视功能,提高患者生活质量。

低视力;可穿戴电子设备;黄斑裂孔;生物反馈训练;低视力康复;扩展现实;优选视网膜位点;受训视网膜位点
ABSTRACT

ObjectiveTo evaluate the short-term rehabilitation effect of wearable visual training devices based on extended reality (XR) glasses in patients after macular hole surgery.

MethodsA self-controlled study was conducted.Eleven patients with monocular low vision after macular hole surgery were recruited at Renmin Hospital of Wuhan University from October 2022 to March 2024.All patients underwent biofeedback training for 3 months using the independently developed visual rehabilitation training glasses LOOKBON T10.The LogMAR best corrected visual acuity (BCVA), retinal sensitivity, effective fixation rate, fixation stability, reading speed, vertical metamorphopsia (MV), horizontal metamorphopsia (MH), and Chinese version of the visual-related quality of life assessment form (CVRQoL-25) were compared before and after training.This study adhered to the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Renmin Hospital of Wuhan University (No.WDRY2024-K263).Written informed consent was obtained from each subject.

ResultsAfter training, the patients' BCVA, retinal sensitivity, effective fixation rate, fixation stability, and reading speed were 0.69±0.19, (21.61±2.75)db, (92.43±4.06)%, (93.09±4.31)%, and (104.82±21.85) characters/minute, respectively, which were significantly improved compared to 0.85±0.28, (17.71±3.17)db, (31.83±19.05)%, (32.35±19.12)%, and (69.64±20.17) characters/minute before training ( t=5.253, -5.987, -11.561, -12.003, -11.682; all at P<0.001).After training, MV and MH were (0.29±0.20)° and (0.21±0.24)°, respectively, which were significantly reduced compared to pre-training (0.44±0.24)° and (0.43±0.41)° ( t=9.238, 4.068; both at P<0.01).After training, the CVRQoL-25 score was 1 193.18±229.43, which was significantly higher than pre-training 947.73±203.86 ( t=-11.687, P<0.001).

ConclusionsThe application of wearable visual training equipment based on XR glasses can effectively improve the visual function of patients with poor visual function recovery after macular hole surgery, and enhance their quality of life.

Low vision;Wearable electronic devices;Macular hole;Biofeedback training;Low vision rehabilitation;Extended reality;Preferred retinal localization;Trained retinal localization
Yuan Jing, Email: mocdef.3ab61117jyx
引用本文

袁静,王兴昌,孙锡全,等. 基于扩展现实的眼镜式可穿戴视觉训练系统在黄斑裂孔术后患者康复中的应用[J]. 中华实验眼科杂志,2024,42(12):1142-1147.

DOI:10.3760/cma.j.cn115989-20240731-00217

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价
黄斑裂孔是指黄斑中心区域视网膜上皮层的组织缺损,一旦裂孔发展到全层,患者会出现中心视力减退和中心暗点,从而显著影响患者的生活质量 [ 1 ]。手术是目前临床上治疗黄斑裂孔的唯一方式,但部分患者术后的中心视功能仍难以恢复,表现为中心暗点、视物变形等。既往研究表明,借助微视野计,通过生物反馈训练(biofeedback training,BFT)有目的反复训练黄斑中心凹旁优选视网膜位点(preferred retinal localization,PRL)或受训视网膜位点(trained retinal localization,TRL),能将视觉系统训练到一个新的功能状态,进而促进视网膜-大脑的信息传递,实现视觉重塑,改善黄斑裂孔术后中心视力损伤患者的视觉功能 [ 2 , 3 , 4 ]。但微视野计的应用场景目前仅在医院,行动不便或特殊时期有需求的患者可能很难长时间坚持往返医院,导致训练后长期效果回退。近年来,随着头戴式显示器和大数据分析技术的迅速发展,有望开发出小型化的可穿戴设备,以方便患者居家训练,可为中心视力损伤患者的主动视觉康复训练提供一种新的技术手段。本研究团队前期开发了一款基于扩展现实(extended reality,XR)的眼镜式视觉康复训练设备 [ 5 ],该设备具备智能化、便携化及小型化的可穿戴效果,借助XR眼镜可实现数字化视野检测及BFT。本研究拟评价该设备短期使用对黄斑裂孔术后患者的康复效果,为其临床应用提供参考依据。
试读结束,您可以通过登录机构账户或个人账户后获取全文阅读权限。
参考文献
[1]
Burton MJ Ramke J Marques AP et al. The Lancet Global Health Commission on Global Eye Health:vision beyond 2020[J/OL]. Lancet Glob Health 20219(4)∶e489e551[2024-07-10]. https://pubmed.ncbi.nlm.nih.gov/33607016/. DOI: 10.1016/S2214-109X(20)30488-5 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
国家重点研发计划2020YFC2008200项目组中华医学会眼科学分会眼视光学组中国医师协会眼科医师分会眼视光专业委员会中国低视力康复临床指南(2021)[J]. 中华眼视光学与视觉科学杂志 202123(3)∶161170. DOI: 10.3760/cma.j.cn115909-20210221-00068 .
返回引文位置Google Scholar
百度学术
万方数据
Research Panel of the National Key R & D Project 2020YFC2008200 Chinese Optometric Association of Chinese Ophthalmological SocietyOptometry Committee of Chinese Ophthalmologists Association. Chinese low vision rehabilitation clinical guideline (2021)[J]. Chin J Optom Ophthalmol Vis Sci 202123(3)∶161170. DOI: 10.3760/cma.j.cn115909-20210221-00068 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[3]
俞素勤许迅中国黄斑病变低视力患者康复训练的专家共识[J]. 中华眼底病杂志 202339(5)∶360367. DOI: 10.3760/cma.j.cn511434-20230404-00150 .
返回引文位置Google Scholar
百度学术
万方数据
Yu SQ Xu X Expert consensus on low vision rehabilitation for patients with macular disease in China[J]. Chin J Ocul Fundus Dis 202339(5)∶360367. DOI: 10.3760/cma.j.cn511434-20230404-00150 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[4]
Sborgia G Niro A Tritto T et al. Microperimetric biofeedback training after successful inverted flap technique for large macular hole[J/OL]. J Clin Med 20209(2)∶556[2024-07-10]. https://pubmed.ncbi.nlm.nih.gov/32085592/. DOI: 10.3390/jcm9020556 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
王倩王兴昌孙锡全基于拓展现实的视觉障碍康复训练设备、系统及方法[P].中国专利: CN117357381A2024-01-09.
返回引文位置Google Scholar
百度学术
万方数据
[6]
葛丽娜张旭沈丽君特发性黄斑裂孔手术后视物变形及视觉相关生存质量评估及影响因素的研究[J]. 中华眼底病杂志 201733(2)∶153156. DOI: 10.3760/cma.j.issn.1005-1015.2017.02.010 .
返回引文位置Google Scholar
百度学术
万方数据
Ge LN Zhang X Shen LJ . Metamorphopsia and vision-related quality of life and its influencing factor after surgical treatment of idiopathic macular hole[J]. Chin J Ocul Fundus Dis 201733(2)∶153156. DOI: 10.3760/cma.j.issn.1005-1015.2017.02.010 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[7]
黄江刘晓玲中文视功能相关生存质量量表-25的初步应用评价[J]. 中华眼视光学与视觉科学杂志 201618(11)∶660664. DOI: 10.3760/cma.j.issn.1674-845X.2016.11.005 .
返回引文位置Google Scholar
百度学术
万方数据
Huang J Liu XL . Development and evaluation of Chinese version vision-related quality of life questionnaire-25[J]. Chin J Optom Ophthalmol Vis Sci 201618(11)∶660664. DOI: 10.3760/cma.j.issn.1674-845X.2016.11.005 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[8]
Bozkurt Oflaz A Turgut Öztürk B Gönül Ş et al. Short-term clinical results of preferred retinal locus training[J]. Turk J O phthalmol 202252(1)∶1422. DOI: 10.4274/tjo.galenos.2021.73368 .
返回引文位置Google Scholar
百度学术
万方数据
[9]
Tarita-Nistor L Mandelcorn MS . Binocularity principles of PRL development in patients with macular disease[J/OL]. Invest Ophthalmol Vis Sci 202263(9)∶19[2024-07-10]. https://pubmed.ncbi.nlm.nih.gov/35976637/. DOI: 10.1167/iovs.63.9.19 .
返回引文位置Google Scholar
百度学术
万方数据
[10]
Tarita-Nistor L Mandelcorn MS Mandelcorn ED et al. Effect of disease progression on the PRL location in patients with bilateral central vision loss[J/OL]. Transl Vis Sci Technol 20209(8)∶47[2024-07-11]. htt ps://pubmed.ncbi.nlm.nih.gov/32855893/ . DOI: 10.1167/tvst.9.8.47 .
返回引文位置Google Scholar
百度学术
万方数据
[11]
Bernard JB Chung S Visual acuity is not the best at the preferred retinal locus in people with macular disease[J]. Optom Vis Sci 201895(9)∶829836. DOI: 10.1097/OPX.0000000000001229 .
返回引文位置Google Scholar
百度学术
万方数据
备注信息
A
袁静,Email: mocdef.3ab61117jyx
B

袁静:设计试验、指导研究、论文撰写及定稿;王兴昌:设备的制备和维护、收集数据、分析和解释数据、论文修改;孙锡全、焦辉广:设备的制备和维护、收集数据、分析和解释数据;王倩、俞建雄:数据统计、分析和解释数据;涂碧玥:实施研究、数据统计、分析和解释数据;严茜茜、赵振、童艳霞、张书文:实施研究、收集数据

C
所有作者均声明不存在利益冲突
D
湖北省重点研发计划 (2021BCA125)
评论 (0条)
注册
登录
时间排序
暂无评论,发表第一条评论抢沙发
MedAI助手(体验版)
文档即答
智问智答
机器翻译
回答内容由人工智能生成,我社无法保证其准确性和完整性,该生成内容不代表我们的态度或观点,仅供参考。
生成快照
文献快照

你好,我可以帮助您更好的了解本文,请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持:

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号