高级检索
中华皮肤科杂志
期刊首页
过刊列表
高级检索
稿件发表
• 指南与共识·老年皮肤病 •
ENGLISH ABSTRACT
老年皮肤瘙痒症诊疗与康复专家共识（2025版）
中国康复医学会皮肤病康复专业委员会
中国中西医结合学会皮肤性病专业委员会老年皮肤病学组
作者及单位信息
·
DOI： 10.35541/cjd.20240407
Expert consensus on the diagnosis, treatment, and rehabilitation of pruritus in the elderly (2025 edition)
Chinese Association of Rehabilitation Dermatology
Working Group on Geriatric Dermatology, Combination} of Traditional and Western Medicine Dermatology
Wang Hongwei
Xie Zhiqiang
Authors Info & Affiliations
Chinese Association of Rehabilitation Dermatology
Working Group on Geriatric Dermatology, Combination} of Traditional and Western Medicine Dermatology
Wang Hongwei
Xie Zhiqiang
·
DOI： 10.35541/cjd.20240407
405
165
0
0
5
1
PDF下载
APP内阅读
摘要

近年来，国内外老年皮肤瘙痒症研究进展迅速，对该病的认识也越来越深入。为规范老年皮肤瘙痒症的诊疗与康复，中国康复医学会皮肤病康复专业委员会、中国中西医结合学会皮肤性病专业委员会老年皮肤病学组组织相关专家，结合国内外最新研究进展，特别是一些循证医学证据，制订了《老年皮肤瘙痒症诊疗与康复专家共识（2025版）》，为解决临床实际问题、缓解或消除患者症状、提高患者生活质量提供建议。

瘙痒症;老年人;诊断;治疗;康复;专家共识
ABSTRACT

In recent years, research on pruritus in the elderly has progressed rapidly, deepening the understanding of this condition. In order to standardize the diagnosis, treatment and rehabilitation of pruritus in the elderly, experts from the Chinese Association Rehabilitation of Dermatology, and the Working Group on Geriatric Dermatology, Combination of Traditional and Western Medicine Dermatology organized relevant experts and formulated an expert consensus on the diagnosis, treatment, and rehabilitation of pruritus in the elderly (2025 edition) based on the latest Chinese and international research advancements, with a particular focus on evidence-based medicine. This consensus aims to provide recommendations to address clinical problems, alleviate or eliminate patients′ symptoms and improve their quality of life.

Pruritus;Aged;Diagnosis;Therapy;Rehabilitation;Expert consensus
Wang Hongwei, Email: mocdef.nabuyila5002gnawiewgnoh
Xie Zhiqiang, Email: mocdef.3ab6166qzeix
Copyright by Chinese Medical Association
No content published by the journals of Chinese Medical Association may be reproduced or abridged without authorization. Please do not use or copy the layout and design of the journals without permission.
All articles published represent the opinions of the authors, and do not reflect the official policy of the Chinese Medical Association or the Editorial Board, unless this is clearly specified.
引用本文

中国康复医学会皮肤病康复专业委员会,中国中西医结合学会皮肤性病专业委员会老年皮肤病学组. 老年皮肤瘙痒症诊疗与康复专家共识（2025版）[J]. 中华皮肤科杂志,2025,58(01)：1-8.

DOI:10.35541/cjd.20240407

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价

版权归中华医学会所有。

未经授权，不得转载、摘编本刊文章，不得使用本刊的版式设计。

除非特别声明，本刊刊出的所有文章不代表中华医学会和本刊编委会的观点。

皮肤瘙痒症是老年人群中最常见的临床病症之一，病因复杂，可源于皮肤病和非皮肤病，也可能病因不清 [ 1 ]，其发病率随年龄增加而逐渐升高 [ 2 , 3 ]。我国60岁以上老年人群中瘙痒症总患病率为31.0% [ 4 ]。2018年版世界卫生组织国际疾病分类（ICD）11首次针对衰老相关疾病纳入了扩展代码"Ageing-Related衰老相关"（XT9T），即衰老是一个年龄相关疾病的重要危险因素，或将衰老作为年龄相关疾病病因 [ 5 ]，老年皮肤瘙痒症属于一种衰老相关的疾病或综合征 [ 6 , 7 , 8 ]。本专家组在复习相关文献及充分讨论的基础上，针对定义、疾病分类、诊断标准及治疗等方面达成共识，推荐给皮肤科医生及全科医生临床实践参考。
试读结束，您可以通过登录机构账户或个人账户后获取全文阅读权限。
参考文献
[1]
Valdes-Rodriguez R , Stull C , Yosipovitch G . Chronic pruritus in the elderly: pathophysiology, diagnosis and management[J]. Drugs Aging, 2015,32(3):201-215. doi: 10.1007/s40266-015-0246-0 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Yalçin B , Tamer E , Toy GG ,et al. The prevalence of skin diseases in the elderly: analysis of 4099 geriatric patients[J]. Int J Dermatol, 2006,45(6):672-676. doi: 10.1111/j.1365-4632.2005.02607.x .
返回引文位置Google Scholar
百度学术
万方数据
[3]
Ju Y , Pei H , Kang N ,et al. Prevalence and potential risk factors of chronic pruritus among community middle-aged and older population in Beijing, China[J]. J Eur Acad Dermatol Venereol, 2022,36(7):1074-1079. doi: 10.1111/jdv.18041 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
陈师，高静，柏丁兮,等. 中国老年性皮肤瘙痒症患病率的Meta分析[J]. 中国循证医学杂志, 2020,20(5):562-567. doi: 10.7507/1672-2531.201910023 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
Calimport S , Bentley BL . Aging classified as a cause of disease in ICD-11[J]. Rejuvenation Res, 2019,22(4):281. doi: 10.1089/rej.2019.2242 .
返回引文位置Google Scholar
百度学术
万方数据
[6]
Clerc CJ , Misery L . A literature review of senile pruritus: from diagnosis to treatment[J]. Acta Derm Venereol, 2017,97(4):433-440. doi: 10.2340/00015555-2574 .
返回引文位置Google Scholar
百度学术
万方数据
[7]
谢志强. 老年瘙痒症:从症状到疾病[J]. 皮肤科学通报, 2019,36(4):480-490.
返回引文位置Google Scholar
百度学术
万方数据
[8]
Abel MK , Jelousi S , Berger T ,et al. Immunological eruptions of ageing: reframing chronic pruritic rashes in older adults[J]. Br J Dermatol, 2021,185(3):638-639. doi: 10.1111/bjd.20414 .
返回引文位置Google Scholar
百度学术
万方数据
[9]
中国中西医结合学会皮肤性病专业委员会老年皮肤病学组. 老年皮肤瘙痒症诊断与治疗专家共识[J]. 中国皮肤性病学杂志, 2018,32(11):1233-1237. doi: 10.13735/j.cjdv.1001-7089.201808168 .
返回引文位置Google Scholar
百度学术
万方数据
[10]
Berger TG , Steinhoff M . Pruritus in elderly patients--eruptions of senescence[J]. Semin Cutan Med Surg, 2011,30(2):113-117. doi: 10.1016/j.sder.2011.04.002 .
返回引文位置Google Scholar
百度学术
万方数据
[11]
Steinhoff M , Al-Khawaga S , Buddenkotte J . Itch in elderly patients: origin, diagnostics, management[J]. J Allergy Clin Immunol, 2023,152(1):42-49. doi: 10.1016/j.jaci.2023.05.009 .
返回引文位置Google Scholar
百度学术
万方数据
[12]
Roh YS , Khanna R , Patel SP ,et al. Circulating blood eosinophils as a biomarker for variable clinical presentation and therapeutic response in patients with chronic pruritus of unknown origin [J]. J Allergy Clin Immunol Pract, 2021,9(6):2513-2516.e2. doi: 10.1016/j.jaip.2021.01.034 .
返回引文位置Google Scholar
百度学术
万方数据
[13]
Roh YS , Choi J , Sutaria N ,et al. Itch: epidemiology, clinical presentation, and diagnostic workup[J]. J Am Acad Dermatol, 2022,86(1):1-14. doi: 10.1016/j.jaad.2021.07.076 .
返回引文位置Google Scholar
百度学术
万方数据
[14]
中国医师协会皮肤科医师分会. 慢性瘙痒管理指南（2024版）[J]. 中华皮肤科杂志, 2024,57(5):387-399. doi: 10.35541/cjd.20230746 .
返回引文位置Google Scholar
百度学术
万方数据
[15]
Reich A , Chatzigeorkidis E , Zeidler C ,et al. Tailoring the cut-off values of the visual analogue scale and numeric rating scale in itch assessment[J]. Acta Derm Venereol, 2017,97(6):759-760. doi: 10.2340/00015555-2642 .
返回引文位置Google Scholar
百度学术
万方数据
[16]
谢志强，傅君舟，陈敢,等. 改良川岛瘙痒严重度评价方法与视觉模拟评分法的相关性[J]. 中国医学科学院学报, 2018,40(4):539-542. doi: 10.3881/j.issn.1000-503X.10320 .
返回引文位置Google Scholar
百度学术
万方数据
[17]
Bastien CH , Vallières A , Morin CM . Validation of the insomnia severity index as an outcome measure for insomnia research[J]. Sleep Med, 2001,2(4):297-307. doi: 10.1016/s1389-9457(00)00065-4 .
返回引文位置Google Scholar
百度学术
万方数据
[18]
Zigmond AS , Snaith RP . The hospital anxiety and depression scale[J]. Acta Psychiatr Scand, 1983,67(6):361-370. doi: 10.1111/j.1600-0447.1983.tb09716.x .
返回引文位置Google Scholar
百度学术
万方数据
[19]
Finlay AY , Khan GK . Dermatology life quality index （DLQI）--a simple practical measure for routine clinical use[J]. Clin Exp Dermatol, 1994,19(3):210-216. doi: 10.1111/j.1365-2230.1994.tb01167.x .
返回引文位置Google Scholar
百度学术
万方数据
[20]
Choi EH . Gender, age, and ethnicity as factors that can influence skin pH[J]. Curr Probl Dermatol, 2018,54:48-53. doi: 10.1159/000489517 .
返回引文位置Google Scholar
百度学术
万方数据
[21]
Wang Z , Man MQ , Li T ,et al. Aging-associated alterations in epidermal function and their clinical significance[J]. Aging （Albany NY）, 2020,12(6):5551-5565. doi: 10.18632/aging.102946 .
返回引文位置Google Scholar
百度学术
万方数据
[22]
Wang B , Han J , Elisseeff JH ,et al. The senescence-associated secretory phenotype and its physiological and pathological implications[J]. Nat Rev Mol Cell Biol, 2024,25(12):958-978. doi: 10.1038/s41580-024-00727-x .
返回引文位置Google Scholar
百度学术
万方数据
[23]
Du LX , Zhu JY , Mi WL . Cytokines and chemokines modulation of itch[J]. Neuroscience, 2022,495:74-85. doi: 10.1016/j.neuroscience.2022.05.035 .
返回引文位置Google Scholar
百度学术
万方数据
[24]
Mansfield AS , Nevala WK , Dronca RS ,et al. Normal ageing is associated with an increase in Th2 cells, MCP-1 （CCL1） and RANTES （CCL5）, with differences in sCD40L and PDGF-AA between sexes[J]. Clin Exp Immunol, 2012,170(2):186-193. doi: 10.1111/j.1365-2249.2012.04644.x .
返回引文位置Google Scholar
百度学术
万方数据
[25]
Terekhova M , Swain A , Bohacova P ,et al. Single-cell atlas of healthy human blood unveils age-related loss of NKG2C（+）GZMB（-）CD8（+） memory T cells and accumulation of type 2 memory T cells[J]. Immunity, 2024,57(1):188-192. doi: 10.1016/j.immuni.2023.12.014 .
返回引文位置Google Scholar
百度学术
万方数据
[26]
Oetjen LK , Mack MR , Feng J ,et al. Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch[J]. Cell, 2017,171(1):217-228.e13. doi: 10.1016/j.cell.2017.08.006 .
返回引文位置Google Scholar
百度学术
万方数据
[27]
Sutaria N , Adawi W , Goldberg R ,et al. Itch: pathogenesis and treatment[J]. J Am Acad Dermatol, 2022,86(1):17-34. doi: 10.1016/j.jaad.2021.07.078 .
返回引文位置Google Scholar
百度学术
万方数据
[28]
Feng J , Luo J , Yang P ,et al. Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itch[J]. Science, 2018,360(6388):530-533. doi: 10.1126/science.aar5703 .
返回引文位置Google Scholar
百度学术
万方数据
[29]
Hadad R , Mandelli ML , Rankin KP ,et al. Itching frequency and neuroanatomic correlates in frontotemporal lobar degeneration[J]. JAMA Neurol, 2024,81(9):977-984. doi: 10.1001/jamaneurol.2024.2213 .
返回引文位置Google Scholar
百度学术
万方数据
[30]
Bressler R , Bahl JJ . Principles of drug therapy for the elderly patient[J]. Mayo Clin Proc, 2003,78(12):1564-1577. doi: 10.4065/78.12.1564 .
返回引文位置Google Scholar
百度学术
万方数据
[31]
Nowak DA , Yeung J . Diagnosis and treatment of pruritus[J]. Can Fam Physician, 2017,63(12):918-924.
返回引文位置Google Scholar
百度学术
万方数据
[32]
程淋 燕 ，王怡，卫颖漪,等. 三亚油酸甘油酯对皮肤屏障的保护作用研究[J]. 皮肤科学通报, 2024,41(03):299-304.
返回引文位置Google Scholar
百度学术
万方数据
[33]
Wang Y , Lu H , Cheng L ,et al. Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: a triacylglycerol from the medicinal plant Cannabis fructus[J]. Phytomedicine, 2024,132:155856. doi: 10.1016/j.phymed.2024.155856 .
返回引文位置Google Scholar
百度学术
万方数据
[34]
Katayama I , Aihara M , Ohya Y ,et al. Japanese guidelines for atopic dermatitis 2017[J]. Allergol Int, 2017,66(2):230-247. doi: 10.1016/j.alit.2016.12.003 .
返回引文位置Google Scholar
百度学术
万方数据
[35]
Hayama K , Takano Y , Tamura J ,et al. Effectiveness of a heparinoid-containing moisturiser to treat senile xerosis[J]. Australas J Dermatol, 2015,56(1):36-39. doi: 10.1111/ajd.12179 .
返回引文位置Google Scholar
百度学术
万方数据
[36]
Valdes-Rodriguez R , Stull C , Yosipovitch G . Chronic pruritus in the elderly: pathophysiology, diagnosis and management[J]. Drugs Aging, 2015,32(3):201-215. doi: 10.1007/s40266-015-0246-0 .
返回引文位置Google Scholar
百度学术
万方数据
[37]
<x>Nowa</x> <x>k</x> DA , Yeung J . Diagnosis and treatment of pruritus[J]. Can Fam Physician, 2017,63(12):918-924.
返回引文位置Google Scholar
百度学术
万方数据
[38]
Grozdev IS , Van Voorhees AS , Gottlieb AB ,et al. Psoriasis in the elderly: from the medical board of the national psoriasis foundation[J]. J Am Acad Dermatol, 2011,65(3):537-545. doi: 10.1016/j.jaad.2010.05.014 .
返回引文位置Google Scholar
百度学术
万方数据
[39]
Al-Ghnaniem R , Short K , Pullen A ,et al. 1% hydrocortisone ointment is an effective treatment of pruritus ani: a pilot randomized controlled crossover trial[J]. Int J Colorectal Dis, 2007,22(12):1463. doi: 10.1007/s00384-007-0325-8 .
返回引文位置Google Scholar
百度学术
万方数据
[40]
Sher LG , Chang J , Patel IB ,et al. Relieving the pruritus of atopic dermatitis: a meta-analysis[J]. Acta Derm Venereol, 2012,92(5):455-461. doi: 10.2340/00015555-1360 .
返回引文位置Google Scholar
百度学术
万方数据
[41]
Duque MI , Yosipovitch G , Fleischer AB Jr,et al. Lack of efficacy of tacrolimus ointment 0.1% for treatment of hemodialysis-related pruritus: a randomized, double-blind, vehicle-controlled study[J]. J Am Acad Dermatol, 2005,52(3):Pt 1-519. 521doi: 10.1016/j.jaad.2004.08.050 .
返回引文位置Google Scholar
百度学术
万方数据
[42]
Yosipovitch G , Gold LF , Lebwohl MG ,et al. Early relief of pruritus in atopic dermatitis with crisaborole ointment, a non-steroidal, phosphodiesterase 4 inhibitor[J]. Acta Derm Venereol, 2018,98(5):484-489. doi: 10.2340/00015555-2893 .
返回引文位置Google Scholar
百度学术
万方数据
[43]
Ciechanowicz P , Rakowska A , Sikora M ,et al. JAK-inhibitors in dermatology: current evidence and future applications[J]. J Dermatolog Treat, 2019,30(7):648-658. doi: 10.1080/09546634.2018.1546043 .
返回引文位置Google Scholar
百度学术
万方数据
[44]
Chen X , Han X , Cheng B ,et al. Efficacy and safety of bilastine vs . levocetirizine for the treatment of chronic idiopathic urticaria: a multicenter, double-blind, double-dummy, phase Ⅲ, non-inferiority, randomized clinical trial [J]. Chin Med J （Engl）, 2024,137(12):1480-1482. doi: 10.1097/CM9.0000000000003071 .
返回引文位置Google Scholar
百度学术
万方数据
[45]
中国中西医结合学会皮肤性病专业委员会环境与职业性皮肤病学组. 抗组胺药在皮肤科应用专家共识[J]. 中华皮肤科杂志, 2017,50(6):393-396. doi: 10.3760/cma.j.issn.0412-4030.2017.06.001 .
返回引文位置Google Scholar
百度学术
万方数据
[46]
Yasuda KI , Ishiuji Y , Endo T ,et al. Cyclosporine improves sleep quality in patients with atopic dermatitis[J]. Dermatol Ther （Heidelb）, 2020,10(6):1359-1369. doi: 10.1007/s13555-020-00451-2 .
返回引文位置Google Scholar
百度学术
万方数据
[47]
Wollenberg A , Barbarot S , Bieber T ,et al. Consensus-based European guidelines for treatment of atopic eczema （atopic dermatitis） in adults and children: part Ⅱ[J]. J Eur Acad Dermatol Venereol, 2018,32(6):850-878. doi: 10.1111/jdv.14888 .
返回引文位置Google Scholar
百度学术
万方数据
[48]
Kursewicz C , Valdes-Rodriguez R , Yosipovitch G . Methotrexate in the treatment of chronic itch in the geriatric population[J]. Acta Derm Venereol, 2020,100(1):adv00037. doi: 10.2340/00015555-3360 .
返回引文位置Google Scholar
百度学术
万方数据
[49]
Matsuda KM , Sharma D , Schonfeld AR ,et al. Gabapentin and pregabalin for the treatment of chronic pruritus[J]. J Am Acad Dermatol, 2016,75(3):619-625.e6. doi: 10.1016/j.jaad.2016.02.1237 .
返回引文位置Google Scholar
百度学术
万方数据
[50]
Lee J , Shin JU , Noh S ,et al. Clinical efficacy and safety of naltrexone combination therapy in older patients with severe pruritus[J]. Ann Dermatol, 2016,28(2):159-163. doi: 10.5021/ad.2016.28.2.159 .
返回引文位置Google Scholar
百度学术
万方数据
[51]
Raap U , Ständer S , Metz M . Pathophysiology of itch and new treatments[J]. Curr Opin Allergy Clin Immunol, 2011,11(5):420-427. doi: 10.1097/ACI.0b013e32834a41c2 .
返回引文位置Google Scholar
百度学术
万方数据
[52]
Kumagai H , Ebata T , Takamori K ,et al. Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a phase Ⅲ, randomized, double-blind, placebo-controlled study[J]. Nephrol Dial Transplant, 2010,25(4):1251-1257. doi: 10.1093/ndt/gfp588 .
返回引文位置Google Scholar
百度学术
万方数据
[53]
Weiner DE , Schaufler T , McCafferty K ,et al. Difelikefalin improves itch-related sleep disruption in patients undergoing haemodialysis[J]. Nephrol Dial Transplant, 2024,39(7):1125-1137. doi: 10.1093/ndt/gfad245 .
返回引文位置Google Scholar
百度学术
万方数据
[54]
Alsebayel MM , Alzaid T , Alobaida SA . Dupilumab in acquired perforating dermatosis: a potential new treatment[J]. JAAD Case Rep, 2022,28:34-36. doi: 10.1016/j.jdcr.2022.08.013 .
返回引文位置Google Scholar
百度学术
万方数据
[55]
Jeon J , Wang F , Badic A ,et al. Treatment of patients with chronic pruritus of unknown origin with dupilumab[J]. J Dermatolog Treat, 2022,33(3):1754-1757. doi: 10.1080/09546634.2021.1880542 .
返回引文位置Google Scholar
百度学术
万方数据
[56]
Bal A , Sorensen A , Ondreyco SM . Nonbullous erythrodermic pemphigoid with florid lymphadenopathy, response to dupilumab[J]. JAAD Case Rep, 2021,17:58-60. doi: 10.1016/j.jdcr.2021.09.014 .
返回引文位置Google Scholar
百度学术
万方数据
[57]
Guttman-Yassky E , Bissonnette R , Ungar B ,et al. Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis[J]. J Allergy Clin Immunol, 2019,143(1):155-172. doi: 10.1016/j.jaci.2018.08.022 .
返回引文位置Google Scholar
百度学术
万方数据
[58]
Wu K , Jabbar-Lopez ZK . Omalizumab, an anti-IgE mAb, receives approval for the treatment of chronic idiopathic/spontaneous urticaria[J]. J Invest Dermatol, 2015,135(1):13-15. doi: 10.1038/jid.2014.362 .
返回引文位置Google Scholar
百度学术
万方数据
[59]
中华医学会皮肤性病学分会荨麻疹研究中心. 抗IgE疗法——奥马珠单抗治疗慢性荨麻疹专家共识[J]. 中华皮肤科杂志, 2021,54(12):1057-1062. doi: 10.35541/cjd.20210568 .
返回引文位置Google Scholar
百度学术
万方数据
[60]
Guttman-Yassky E , Thaçi D , <x>Pa</x> <x>ngan</x> AL ,et al. Upadacitinib in adults with moderate to severe atopic dermatitis: 16-week results from a randomized, placebo-controlled trial[J]. J Allergy Clin Immunol, 2020,145(3):877-884. doi: 10.1016/j.jaci.2019.11.025 .
返回引文位置Google Scholar
百度学术
万方数据
[61]
Eichenfield LF , Flohr C , Sidbury R ,et al. Efficacy and safety of abrocitinib in combination with topical therapy in adolescents with moderate-to-severe atopic dermatitis: the JADE TEEN randomized clinical trial[J]. JAMA Dermatol, 2021,157(10):1165-1173. doi: 10.1001/jamadermatol.2021.2830 .
返回引文位置Google Scholar
百度学术
万方数据
[62]
Wang F , Morris C , Bodet ND ,et al. Treatment of refractory chronic pruritus of unknown origin with tofacitinib in patients with rheumatoid arthritis[J]. JAMA Dermatol, 2019,155(12):1426-1428. doi: 10.1001/jamadermatol.2019.2804 .
返回引文位置Google Scholar
百度学术
万方数据
[63]
Buttgereit T , Grekowitz EM , Metz M . Baricitinib rapidly and sustainably relieves a patient from chronic pruritus of unknown origin refractory to dupilumab[J]. JAAD Case Rep, 2021,15:36-38. doi: 10.1016/j.jdcr.2021.06.028 .
返回引文位置Google Scholar
百度学术
万方数据
[64]
Kwatra SG , Bordeaux ZA , Parthasarathy V ,et al. Efficacy and safety of abrocitinib in prurigo nodularis and chronic pruritus of unknown origin: a nonrandomized controlled Trial[J]. JAMA Dermatol, 2024,160(7):717-724. doi: 10.1001/jamadermatol.2024.1464 .
返回引文位置Google Scholar
百度学术
万方数据
[65]
中华中医药学会皮肤科分会. 皮肤瘙痒症中医治疗专家共识[J]. 中国中西医结合皮肤性病学杂志, 2017,16(2):189-190. doi: 10.3969/j.issn.1672-0709.2017.02.036 .
返回引文位置Google Scholar
百度学术
万方数据
[66]
李斌，陈达灿. 中西医结合皮肤性病学[M]. 北京:中国中医药出版社, 2017.
返回引文位置
[67]
Chung BY , Um JY , Kim JC ,et al. Pathophysiology and treatment of pruritus in elderly[J]. Int J Mol Sci, 2020,22(1):174. doi: 10.3390/ijms22010174 .
返回引文位置Google Scholar
百度学术
万方数据
[68]
Schut C , Mollanazar NK , Kupfer J ,et al. Psychological interventions in the treatment of chronic itch[J]. Acta Derm Venereol, 2016,96(2):157-161. doi: 10.2340/00015555-2177 .
返回引文位置Google Scholar
百度学术
万方数据
[69]
凯特林·弗朗卡. 应激与皮肤疾病—从基础到临床[M]. 张海萍,译. 北京:清华大学出版社, 2021.
返回引文位置
备注信息
A
王宏伟，Email： mocdef.nabuyila5002gnawiewgnoh
B
谢志强，Email： mocdef.3ab6166qzeix
C
所有作者均声明无利益冲突
评论 （0条）
注册
登录
时间排序
暂无评论，发表第一条评论抢沙发
最新推荐
更多
老年骨质疏松性肩关节周围骨折诊疗中国专家共识（2023版）
胡衍 等
中华创伤杂志 2023,39(04)
创伤后多器官功能障碍综合征临床诊疗专家共识
中国研究型医院学会休克与脓毒症专业委员会 等
中华危重病急救医学 2022,34(03)
腰椎间盘突出症诊治与康复管理指南
中国康复医学会脊柱脊髓专业委员会基础研究与转化学组
中华外科杂志 2022,60(05)
慢性腰背痛康复中国疼痛科专家共识
国家卫生健康委能力建设和继续教育中心疼痛病诊疗专项能力培训项目专家组 等
中华疼痛学杂志 2021,17(06)
MedAI助手（体验版）
文档即答
智问智答
机器翻译
回答内容由人工智能生成，我社无法保证其准确性和完整性，该生成内容不代表我们的态度或观点，仅供参考。
生成快照
文献快照

你好，我可以帮助您更好的了解本文，请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持：

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号
小中大