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ENGLISH ABSTRACT
多模态医学图像融合在颞下颌关节疾病诊治中的应用进展
赵伟
孙欣荣
冯玥
刘伟才
作者及单位信息
·
DOI： 10.3760/cma.j.cn112144-20241217-00495
Application of multimodal medical image fusion in temporomandibular joint diseases
Zhao Wei
Sun Xinrong
Feng Yue
Liu Weicai
Authors Info & Affiliations
Zhao Wei
Department of Prosthodontics, Stomatological Hospital and Dental School, Tongji University & Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology, Shanghai 200072, China
Sun Xinrong
Department of Prosthodontics, Stomatological Hospital and Dental School, Tongji University & Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology, Shanghai 200072, China
Feng Yue
Department of Prosthodontics, Stomatological Hospital and Dental School, Tongji University & Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology, Shanghai 200072, China
Liu Weicai
Department of Prosthodontics, Stomatological Hospital and Dental School, Tongji University & Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology, Shanghai 200072, China
·
DOI： 10.3760/cma.j.cn112144-20241217-00495
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摘要

随着现代科技的快速发展，计算机与医学的深度融合极大地促进了口腔医学诊断技术向前迈进。多模态医学图像融合是指不同模态医学影像信息的融合，即在计算机技术的帮助下，将所获得的各种影像学检查所得到的影像信息进行空间配准处理，形成一种信息全面的新图像，达到计算机辅助诊断的目的。颞下颌关节解剖结构复杂，颞下颌关节疾病类型多样，传统单一模态的影像学方法只能提供部分解剖结构信息，无法全面评估，也导致了疾病诊治的局限性。多模态医学图像融合技术产品凭借其信息全面等优点已广泛应用于口腔医学领域中，极大提升了颞下颌关节疾病的诊疗效率。本文就多模态医学图像融合在颞下颌关节疾病中的应用进展进行述论。

颞下颌关节;多模态医学图像融合;磁共振;锥形束CT;三维重建
ABSTRACT

With the rapid development of modern technology, the deep integration of computer science and medicine has greatly propelled the field of the dental diagnostics field. Multimodal medical image registration refers to the fusion of information from various modalities of medical imaging. In other words, with the assistance of computer technology, the image data acquired from various radiological examinations undergo spatial registration and are merged to create a comprehensive new image, serving the purpose of computer-aided diagnosis. The temporomandibular joint (TMJ) has complex anatomical structures, so there is a wide range of diseases associated with it. Traditional single-modal imaging methods can only provide partial anatomical information, which limits the comprehensive assessment and subsequently hinders the diagnosis and treatment of TMJ diseases. Multimodal medical image registration techniques, owing to their ability to provide comprehensive information, have been widely applied in the field of dentistry. This has greatly enhanced the efficiency of diagnosing and treating TMJ diseases. The article discusses the advancements in the application of multimodal medical image registration in the context of TMJ diseases.

Temporomandibular joint;Multimodal medical image fusion;Magnetic resonance imaging;Cone-beam CT;Three-dimensional reconstruction
Liu Weicai, Email: mocdef.3ab61igov, Tel: 0086-21-66315021
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引用本文

赵伟,孙欣荣,冯玥,等. 多模态医学图像融合在颞下颌关节疾病诊治中的应用进展[J]. 中华口腔医学杂志,2025,60(03)：296-301.

DOI:10.3760/cma.j.cn112144-20241217-00495

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近年来，医学图像融合作为医学领域的重要方法，受到了广泛关注。目前，临床中使用的多种医学成像模式下形成的各模态影像，均具有一定的局限性。例如，CT对骨组织和牙体组织显影良好，而对关节盘等软组织几乎不显影 ［ 1 ］ ；MRI可分析颞下颌关节（temporomandibular joint，TMJ）关节盘位置和形态 ［ 2 ］ ，但其定位关节盘在髁突和关节窝的相对位置时准确性欠佳 ［ 3 ］ ，在TMJ骨质地、形态检测方面灵敏度较低 ［ 4 ］ 。多模态医学图像融合技术是指将MRI、锥形束CT等不同成像机制的医学图像进行配准与融合，使各图像优势互补，得到解剖与功能信息结合的新整体 ［ 5 , 6 ］ 。它可以清晰地描述软组织周围骨骼关节结构的轮廓，优化TMJ的解剖学定义，从而提高临床决策的可靠性 ［ 7 ］ 。
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备注信息
A
刘伟才，Email： mocdef.3ab61igov，电话：021-66315021
B

赵伟：研究设计、文章撰写及修改、对文章的知识性内容作批评性审阅；孙欣荣：研究设计、统计分析；冯玥：数据采集、统计分析；刘伟才：文章的知识性内容作批评性审阅、经费支持

C
赵伟, 孙欣荣, 冯玥, 等. 多模态医学图像融合在颞下颌关节疾病诊治中的应用进展[J]. 中华口腔医学杂志, 2025, 60(3): 296-301. DOI: 10.3760/cma.j.cn112144-20241217-00495.
D
所有作者声明不存在利益冲突
E
上海申康医院发展中心临床三年行动计划——临床研究青年项目 (SHDC2020CR4088)
上海市科学技术委员会科研计划 (21Y11903800)
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