下肢骨折诊治的前沿问题
ENGLISH ABSTRACT
新型交锁髓内钉固定AO分型32-A3型股骨干骨折的有限元分析
陈培生
林朝晖
林凤飞
陈宾
林东泽
郑科
作者及单位信息
·
DOI: 10.3760/cma.j.cn115530-20241231-00517
A novel interlocking intramedullary nail for type AO 32-A3 femoral shaft fractures: a finite element analysis
Chen Peisheng
Lin Chaohui
Lin Fengfei
Chen Bin
Lin Dongze
Zheng Ke
Authors Info & Affiliations
Chen Peisheng
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
Lin Chaohui
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
Lin Fengfei
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
Chen Bin
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
Lin Dongze
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
Zheng Ke
Department of Orthopaedics, Fuzhou Second General Hospital, School of Clinical Medicine, Fujian Medical University, Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma, Fuzhou 350007, China
·
DOI: 10.3760/cma.j.cn115530-20241231-00517
52
12
0
0
2
0
PDF下载
APP内阅读
摘要

目的通过有限元分析方法比较新型交锁髓内钉(nIMN)与传统交锁髓内钉(tIMN)固定AO分型32-A3型股骨干骨折的生物力学稳定性。

方法选择1例健康成年男性志愿者,30岁,体重为70 kg,采集股骨CT扫描数据,应用Mimics 17.0软件和Geomagic Studio软件建立股骨三维有限元模型,模拟AO分型为32-A3a型(上1/3)、32-A3b型(中1/3)、32-A3c型(下1/3)股骨干骨折,并分别与nIMN、tIMN装配。模拟垂直站立、缓步行走、快速行走、下楼梯4种载荷状态,在同一工况下比较2种髓内钉固定方案股骨干骨折断端的位移及应力分布情况,分析各骨折模型不同固定方案的稳定性。

结果在模拟4种载荷时,骨折断端位移平均为0.129 mm,最大应力值平均为111.00 MPa,最小的断端位移、最大应力值分别为0.014 mm、29.48 MPa,均为垂直站立时股骨干下1/3骨折采用nIMN固定,最大的断端位移、最大应力值分别为0.325 mm、242.98 MPa,均为下楼梯时股骨干上1/3骨折采用tIMN固定。对于股骨干上、中、下1/3骨折,不论采用tIMN或nIMN固定,断端位移、最大应力值均随载荷量增加呈现上升趋势,其中上1/3骨折尤为明显。与tIMN相比,nIMN固定股骨干上、中、下1/3骨折的断端位移、最大应力值均更小。以下楼梯载荷为例:股骨整体最大应力值均出现在股骨近端亚当斯弧及其周围部分,范围值为86.62~242.98 MPa;骨折断端最大应力值范围为0.44~56.49 MPa,应力主要集中在内侧部分,且随着股骨上、中、下1/3骨折呈现递减趋势。

结论对于AO分型32-A3型股骨干骨折,nIMN固定较tIMN固定的骨折断端位移和最大应力值均更小,抗旋转稳定性更好。

股骨骨折;骨折固定术,髓内;骨钉;有限元分析;生物力学
ABSTRACT

ObjectiveTo compare the biomechanical stability of a novel interlocking intramedullary nail (nIMN) with that of a traditional interlocking intramedullary nail (tIMN) in the treatment of type AO 32-A3 femoral shaft fractures using a finite element analysis.

MethodsA healthy adult male volunteer, aged 30 years old and weighing 70 kg, was selected for collection of his CT scan data of the femur. A three-dimensional finite element model of the femur was established using software Mimics 17.0 and Geomagic Studio. After femoral shaft fractures of AO/OTA types 32-A3a, 32-A3b, and 32-A3c were simulated, nIMN and tIMN were assembled respectively. After boundary conditions and material properties of the models were set based on reference literature, 4 load states were simulated: vertical standing, slow walking, fast walking, and descending stairs. The displacements and stress distribution at the femoral fracture ends under the same conditions were compared between nIMN and tIMN schemes of fixation. The stabilities of each fracture model at different fixation schemes and load states were analyzed.

ResultsIn the 4 load states simulated, the displacements of the fracture ends averaged 0.129 mm, and the maximum stresses 111.00 MPa. The smallest displacement and maximum stress (0.014 mm and 29.48 MPa) were found in the vertical standing in the femoral shaft fracture of type 32-A3c fixed with nIMN. The largest displacement and maximum stress (0.325 mm and 242.98 MPa) were found in descending stairs in the femoral shaft fracture of type 32-A3a fixed with tIMN. In femoral shaft fractures of types 32-A3a, 32-A3b, and 32-A3c, regardless of tIMN or nIMN fixation, the displacement and maximum stress increased with the load, with the femoral shaft fracture of type 32-A3a being particularly evident. nIMN fixation resulted in lower displacements and maximum stresses in AO/OTA types 32-A3a, 32-A3b, and 32-A3c than tIMN fixation. Taking descending stairs as an example, the overall maximum stress occurred on the proximal part of the femur and the surrounding area of Adams'arc, with the maximum stress fluctuating between 86.62 and 242.98 MPa. The maximum stress at the fracture end fluctuated between 0.44 and 56.49 MPa. The stress mainly concentrated on the medial part, and decreased from type 32-A3a to type 32-A3b to type 32-A3c.

ConclusionIn type AO 32-A3 femoral shaft fractures, nIMN leads to a smaller fracture end displacement and a lower maximum stress than tIMN, indicating better rotational stability.

Femoral fractures;Fracture fixation, intramedullary;Bone nails;Finite element analysis;Biomechanics
Lin Fengfei, Email: mocdef.qabq446855695
引用本文

陈培生,林朝晖,林凤飞,等. 新型交锁髓内钉固定AO分型32-A3型股骨干骨折的有限元分析[J]. 中华创伤骨科杂志,2025,27(03):228-233.

DOI:10.3760/cma.j.cn115530-20241231-00517

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价
随着内固定材料、手术方法的不断改进及人们对骨折治疗观念的转变,目前多趋向于采用手术治疗成人股骨干骨折 [ 1 , 2 ]。股骨交锁髓内钉(interlocking intramedullary nail, IMN)因符合骨组织的力学特性,操作微创,已成为目前治疗股骨干骨折最常用的内固定物 [ 1 , 2 ]。然而,股骨干骨折IMN固定术后骨不连的发生率高达12.5% [ 3 ]。既往研究表明,抗旋转稳定性不足是股骨干骨折术后发生骨不连的主要原因 [ 4 ]。因此,本研究团队设计研制了抗旋转稳定性加强的新型IMN(novel interlocking intramedullary nail,nIMN,中国专利号:ZL 2020 1 0491422.9, ZL 2021 1 0526204.9, ZL 2021 1 0526148.9),在传统IMN(traditional interlocking intramedullary nail,tIMN)的基础上,对4枚横锁钉的位置进行改良,将tIMN横锁钉的位置向骨折断端平移,使骨折端上、下2枚锁钉距离为tIMN长度的1/3,旨在改进tIMN固定股骨干骨折时抗旋转能力不足的问题。为验证nIMN系统在股骨干骨折治疗中的可行性,本研究采用有限元分析方法,建立nIMN固定AO/OTA 32-A3a型(上1/3)、32-A3b型(中1/3)、32-A3c型(下1/3)股骨干骨折的生物力学模型,并与tIMN固定模型进行比较,对比二者的抗旋转稳定性,旨在为nIMN的后续临床推广应用提供理论依据。
试读结束,您可以通过登录机构账户或个人账户后获取全文阅读权限。
参考文献
[1]
Hierholzer C , Glowalla C , Herrler M ,et al. Reamed intramedullary exchange nailing: treatment of choice of aseptic femoral shaft nonunion[J]. J Orthop Surg Res, 2014,9:88. DOI: 10.1186/s13018-014-0088-1 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Hosseini H , Heydari S , Domari AA ,et al. Comparison of treatment results of femoral shaft fracture with two methods of intramedullary nail (IMN) and plate[J]. BMC Surg, 2024,24(1):318. DOI: 10.1186/s12893-024-02590-1 .
返回引文位置Google Scholar
百度学术
万方数据
[3]
Pihlajamaki HK , Salminen ST , Bostman OM . The treatment of nonunions following intramedullary nailing of femoral shaft fractures[J]. J Orthop Trauma, 2002,16(6):394-402. DOI: 10.1097/00005131-200207000-00005 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
Wu T , Zhang W , Chang Z ,et al. Augmented stability in leaving original internal fixation with multidimensional cross locking plate through mini-open femoral anterior approach for aseptic femoral shaft nonunion: a retrospective cohort study[J]. Orthop Surg, 2023,15(1):169-178. DOI: 10.1111/os.13581 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
Perez JV , Warwick DJ , Case CP ,et al. Death after proximal femoral fracture--an autopsy study[J]. Injury, 1995,26(4):237-240. DOI: 10.1016/0020-1383(95)90008-l .
返回引文位置Google Scholar
百度学术
万方数据
[6]
Robinson PS , Placide R , Soslowsky LJ ,et al. Mechanical strength of repairs of the hip piriformis tendon[J]. J Arthroplasty, 2004,19(2):204-210. DOI: 10.1016/j.arth.2003.08.011 .
返回引文位置Google Scholar
百度学术
万方数据
[7]
徐锴,李开南. 三种内固定固定股骨转子间六部分骨折各分型稳定性的有限元分析[J]. 中华创伤骨科杂志, 2019,21(4):345-352. DOI: 10.3760/cma.j.issn.1671-7600.2019.04.013 .
返回引文位置Google Scholar
百度学术
万方数据
Xu K , Li KN . A finite element analysis of fixation with proximal femoral nail antirotation, dynamic hip screw and percutaneous compression plate for six-part intertrochanteric fractures[J]. Chin J Orthop Trauma, 2019,21(4):345-352. DOI: 10.3760/cma.j.issn.1671-7600.2019.04.013 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[8]
汪金平,杨天府,钟凤林,. 股骨生物力学特性的有限元分析[J]. 中华创伤骨科杂志, 2005,7(10):931-934.
返回引文位置Google Scholar
百度学术
万方数据
Wang JP , Yang TF , Zhong FL ,et al. Finite element analysis of the biomechanics of human femur[J]. Chin J Orthop Trauma, 2005,7(10):931-934.
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[9]
王国栋,姜海波,张元民,. 髓内持骨动力性髓内钉固定股骨干骨折的三维有限元分析[J]. 中国组织工程研究, 201418(40):6524-6530. DOI: 10.3969/j.issn.2095-4344.2014.40.022 .
返回引文位置Google Scholar
百度学术
万方数据
Wang GD , Jiang HB , Zhang YM ,et al. Three-dimensional finite element analysis on intramedullary controlled dynamic nailing for femoral shaft fracture[J]. Chinese Journal of Tissue Engineering Research, 2014,18(40):6524-6530. DOI: 10.3969/j.issn.2095-4344.2014.40.022 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[10]
Ghayyad K , Escobar P , Beaudoin TF ,et al. Nonunion fractures: trends in epidemiology and treatment of femur fractures, 2017-2022[J]. Cureus, 2024,16(9):e70566. DOI: 10.7759/cureus.70566 .
返回引文位置Google Scholar
百度学术
万方数据
[11]
Salman LA , Al-Ani A , Radi MFA ,et al. Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis[J]. Int Orthop, 2023,47(12):3031-3041. DOI: 10.1007/s00264-023-05740-x .
返回引文位置Google Scholar
百度学术
万方数据
[12]
柯铁,林昊,蔡鸿儒,. 阻挡钉技术治疗股骨交锁髓内钉术后肥大性骨不连[J]. 中华创伤杂志, 2017,33(4):344-348. DOI: 10.3760/cma.j.issn.1001-8050.2017.04.012 .
返回引文位置Google Scholar
百度学术
万方数据
Ke T , Lin H , Cai HR ,et al. Blocking nail technique for treatment of hypertrophic nonunion after femoral interlocking intramedullary nailing[J]. Chin J Trauma, 2017,33(4):344-348. DOI: 10.3760/cma.j.issn.1001-8050.2017.04.012 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[13]
Johnson KD , Tencer AF , Blumenthal S ,et al. Biomechanical performance of locked intra medullary nail systems in comminuted femoral shaft fractures [J]. Clin Orthop Relat Res, 1986(206):151-161. DOI: 10.1097/00003086-198605000-00028 .
返回引文位置Google Scholar
百度学术
万方数据
[14]
Vaughn JE , Shah RV , Samman T ,et al. Systematic review of dynamization vs exchange nailing for delayed/non-union femoral fractures [J]. World J Orthop, 2018,9(7):92-99. DOI: 10.5312/wjo.v9.i7.92 .
返回引文位置Google Scholar
百度学术
万方数据
[15]
孙贺,孙亮,李忠,. 股骨干骨折术后骨不连的诊疗进展[J]. 骨科, 2020,11(4):344-347. DOI: 10.3969/j.issn.1674-8573.2020.04.015 .
返回引文位置Google Scholar
百度学术
万方数据
Sun H , Sun L , Li Z ,et al. Progress in the diagnosis and treatment of nonunion after femoral shaft fracture[J]. Orthopaedics, 2020,11(4):344-347. DOI: 10.3969/j.issn.1674-8573.2020.04.015 .
Goto CitationGoogle Scholar
Baidu Scholar
Wanfang Data
[16]
Jin YF , Xu HC , Shen ZH ,et al. Comparing augmentative plating and exchange nailing for the treatment of nonunion of femoral shaft fracture after intramedullary nailing: a meta-analysis[J]. Orthop Surg, 2020,12(1):50-57. DOI: 10.1111/os.12580 .
返回引文位置Google Scholar
百度学术
万方数据
[17]
Ueng SW , Chao EK , Lee SS ,et al. Augmentative plate fixation for the management of femoral nonunion after intramedullary nailing[J]. J Trauma, 1997,43(4):640-644. DOI: 10.1097/00005373-199710000-00013 .
返回引文位置Google Scholar
百度学术
万方数据
[18]
Park J , Kim SG , Yoon HK ,et al. The treatment of nonisthmal femoral shaft nonunions with im nail exchange versus augmentation plating[J]. J Orthop Trauma, 2010,24(2):89-94. DOI: 10.1097/BOT.0b013e3181b8dafd .
返回引文位置Google Scholar
百度学术
万方数据
[19]
Perisano C , Cianni L , Polichetti C ,et al. Plate augmentation in aseptic femoral shaft nonunion after intramedullary nailing: a literature review[J]. Bioengineering (Basel), 2022,9(10):60. DOI: 10.3390/bioengineering9100560 .
返回引文位置Google Scholar
百度学术
万方数据
备注信息
A
林凤飞,Email: mocdef.qabq446855695
B

陈培生、林朝晖:研究实施、数据采集、论文撰写;林凤飞:研究设计、技术支持与指导;陈宾、林东泽、郑科:研究实施

C
ZL 2020 1 0491422.9, ZL 2021 1 0526204.9, ZL 2021 1 0526148.9
D
ZL 2020 1 0491422.9, ZL 2021 1 0526204.9, ZL 2021 1 0526148.9
E
所有作者声明无利益冲突
F
福建省自然科学基金面上项目 (2020J011192)
福建省引导性项目 (2022D019,2022-S-004)
福建省创伤骨科急救与康复临床医学研究中心项目 (2020Y2014)
福州市创伤医学中心项目 (2018080303)
评论 (0条)
注册
登录
时间排序
暂无评论,发表第一条评论抢沙发
MedAI助手(体验版)
文档即答
智问智答
机器翻译
回答内容由人工智能生成,我社无法保证其准确性和完整性,该生成内容不代表我们的态度或观点,仅供参考。
生成快照
文献快照

你好,我可以帮助您更好的了解本文,请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持:

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号