首页 中华急诊医学杂志 2025年34卷03期 脑自动调节在危重症领域的研究进展
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脑自动调节在危重症领域的研究进展
韦静静
邓双逍
卞兴航
杨思敏
袁慧琴
周保纯 
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DOI： 10.3760/cma.j.issn.1671-0282.2025.03.032
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摘要
大脑是一个代谢十分活跃的器官，尽管其重量仅占全身体重的2%，但脑血流量（cerebral blood flow, CBF）却占心输出量的15%，脑耗氧量占全身耗氧量的20% [1]，大脑高耗氧量的特点突出了保证脑血流供应的重要性，由此可见脑组织对缺血缺氧的耐受性是极差的，保证充足的脑灌注对于各类颅脑损伤的恢复以及继发性颅脑损伤的防治具有重要意义。
引用本文
韦静静,邓双逍,卞兴航,等. 脑自动调节在危重症领域的研究进展[J]. 中华急诊医学杂志,2025,34(03)：455-460.
DOI:10.3760/cma.j.issn.1671-0282.2025.03.032PERMISSIONS
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大脑是一个代谢十分活跃的器官，尽管其重量仅占全身体重的2%，但脑血流量（cerebral blood flow, CBF）却占心输出量的15%，脑耗氧量占全身耗氧量的20%
[
1
]，大脑高耗氧量的特点突出了保证脑血流供应的重要性，由此可见脑组织对缺血缺氧的耐受性是极差的，保证充足的脑灌注对于各类颅脑损伤的恢复以及继发性颅脑损伤的防治具有重要意义。
与外周循环不同，CBF的调节机制更加精密和复杂，这些机制包括脑自动调节、血管对血管活性刺激的反应性、神经血管耦合以及内皮依赖性反应
[
2
]。重症监护病房中的患者常常存在脑功能异常，脑自主调节功能障碍是神经功能障碍发生的重要原因，本文主要讨论脑自动调节在危重症患者中的研究进展。
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