With the global prevalence of obesity continuing to rise, it has emerged as a critical public health crisis, severely compromising patients' quality of life and impeding socioeconomic development. As a pivo-tal plat-form for chronic disease management, obesity clinics are undergoing a paradigm shift from extensive diag-nostic-treatment models to precision management strategies. Recent years have witnessed breakthrough advance-ments in obesity care, but persistent gaps remain, including insufficient refinement of assessment tools and inade-quate precision in intervention strategies. This article focuses on optimizing obesity clinic frameworks and weight management protocols by examining multidimensional assessment frameworks, multidisciplinary collaboration mechanisms, and precision management systems. Drawing on clinical case studies, we propose a patient-centric obesity care system designed to enhance the scientific rigor and operational efficiency in obesity management. By integrating individualized and continuity-of-care principles, this approach delivers personalized and sustained sup-port for patients while advancing efforts to standardize and homogenize obesity management protocols globally.