褪黑激素及其受体对毛囊的作用

林永丽; 范卫新

doi:10.3760/cma.j.issn.1673-4173.2009.02.026

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国际皮肤性病学杂志

• 综述 •

ENGLISH ABSTRACT

褪黑激素及其受体对毛囊的作用

作者及单位信息

出版日期： 2009 -03 -15 ·

DOI： 10.3760/cma.j.issn.1673-4173.2009.02.026

Effects of melatonin and its receptors on hair follicles

Authors Info & Affiliations

LIN Yong-li

Department of Dermatology,First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China

FAN Wei-xin

Department of Dermatology,First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China

Published： 2009 -03 -15 ·

DOI： 10.3760/cma.j.issn.1673-4173.2009.02.026

166

APP内阅读

摘要

褪黑激素是松果体分泌的主要产物,其生物学作用及其受体在毛囊中的表达与毛发的生长和色素沉着有着密切关系,褪黑激素不仅作用于相应受体,还能通过雄激素受体和雌激素受体介导的信号传导通路起作用,对褪黑激素的深入研究也许可以为毛发疾病的临床治疗提供新的靶点。

关键词：毛囊;褪黑激素;色素沉着

ABSTRACT

Melatonin is the chief product secreted by pineal gland.The biology of melatonin and expression of its receptors in hair follicles have a close connection with hair growth and pigmentation.Melatonin not only interacts with its cognate receptors,but also exerts its role through androgen- and estrogen-receptor-mediated signaling pathways.Further study on melatonin may provide a new target for the treatment of hair diseases.

KEYWORDS： Hair follicle;Melatonin;Pigmentation

引用本文

林永丽,范卫新. 褪黑激素及其受体对毛囊的作用 : [J]. 国际皮肤性病学杂志,2009,35(02)：122-123.

DOI:10.3760/cma.j.issn.1673-4173.2009.02.026

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