特应性皮炎是一种慢性复发性炎症性疾病,紫外线通过调节T细胞功能及相关炎症介质而取得良好疗效.不同波段紫外线因其特性而应用于不同类型的特应性皮炎:窄谱中波紫外线治疗儿童期特应性皮炎显示出良好疗效及安全性,认为是慢性患者的首选治疗;急性患者首选长波紫外线照射;局限性皮损选择308 nm准分子激光为佳.紫外线治疗特应性皮炎临床尚处于初级阶段,在照射剂量和照射疗程方面,各家报道不一。
Atopic dermatitis is a chronic recurrent inflammatory disease.By regulating the function of T cells and related inflammation factors,ultraviolet rays (UV) exert a satisfactory therapeutic effect on atopic dermatitis.Because of distinct characteristics,different spectrum of UV is applicable to specific types of atopic dermatitis.Narrow-band UVB shows good efficacy and safety in the treatment of atopic dermatitis in childhood,and is considered to be the best choice for patients with chronic atopic dermatitis; UVA is the preferred choice for patients with acute atopic dermatitis,and 308-nm excimer laser is suitable for local lesions of atopic dermatitis.However,there has been no uniform standard for the dose and duration of UV irradiation in the treatment of atopic dermatitis.
周飞红,喻雅也,李东升. 紫外线治疗特应性皮炎的进展 : [J]. 国际皮肤性病学杂志,2013,39(01):38-41.
DOI:10.3760/cma.j.issn.1673-4173.2013.01.013
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