经验交流
ENGLISH ABSTRACT
肺不典型类癌五例临床分析
王磊
袁茂玲
彭妍
俞鹏翼
汪潜云
王中林
作者及单位信息
·
DOI: 10.3760/cma.j.issn.1671-7368.2016.10.017
Clinical analysis of 5 cases of atypical pulmonary carcinoid
Wang Lei
Yuan Maoling
Peng Yan
Yu Pengyi
Wang Qianyun
Wang Zhonglin
Authors Info & Affiliations
Wang Lei
Department of Gastrointestinal Surgery, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
Yuan Maoling
Department of Geriatric Medicine, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
Peng Yan
Department of Patholoby, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
Yu Pengyi
Department of Thoracic Surgery, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
Wang Qianyun
Department of Thoracic Surgery, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
Wang Zhonglin
Department of Thoracic Surgery, the First People′s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
·
DOI: 10.3760/cma.j.issn.1671-7368.2016.10.017
542
31
0
0
0
0
PDF下载
APP内阅读
摘要

回顾分析2000年1月至2015年12月诊治、病理确诊的5例不典型类癌患者的临床资料。5例中,男2例,女3例,年龄39~76岁;体检发现2例,刺激性干咳2例,胸痛1例,咯血1例,痰中带血1例,均无类癌综合征表现。血癌胚抗原水平偏高1例;CT检查均提示占位病变;痰细胞学检查均阴性;4例行纤维支气管镜检查阳性。均行手术治疗,2例辅以化疗。术后随访24~58个月,1例术后1年发现前列腺癌骨转移,带瘤生存,4例无瘤生存。提示,肺不典型类癌临床少见,术前诊断较为困难,术后病理是确诊的主要方法,手术是治疗肺不典型类癌的有效方法,术后需要长期随访。

神经内分泌瘤;
引用本文

王磊,袁茂玲,彭妍,等. 肺不典型类癌五例临床分析[J]. 中华全科医师杂志,2016,15(10):800-801.

DOI:10.3760/cma.j.issn.1671-7368.2016.10.017

PERMISSIONS

Request permissions for this article from CCC.

评价本文
*以上评分为匿名评价
第4版WHO肺、胸膜、胸腺及心脏肿瘤分类于2015年初出版,其首次将小细胞癌(SCLC)、复合性SCLC、大细胞神经内分泌癌(LCNEC )、复合性LCNEC、不典型类癌(atypical carcinoid, AC)、典型类癌(typical carcinoid,TC)及弥漫性特发性的神经内分泌细胞增生(癌前病变)统一归为神经内分泌肿瘤(pulmonary neuroendocrine tumors,pNET) [ 1 ]。其中典型类癌和不典型类癌,分别被划为低度和中度恶性神经内分泌肿瘤,诊断标准同2004版 [ 2 ]。由于AC较少见,对其诊断、治疗和预后等往往难以把握,本文回顾分析我院收治的5例患者临床资料。
试读结束,您可以通过登录机构账户或个人账户后获取全文阅读权限。
参考文献
[1]
Travis WD1 , Brambilla E , Nicholson AG et al. The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification[J]. J Thorac Oncol, 201510(9):1243-1260. DOI: 10.1097/JTO.0000000000000630 .
返回引文位置Google Scholar
百度学术
万方数据
[2]
Travis WD , Brambilla E , Müller-Hermelink HK , et al . Pathology and genetics:tumours of the lung,pleura,thymus and Heart[M]. LyonIARC 2004.
[3]
Naalsund A , Rostad H , Strøm EH ,et al. Carcinoid lung tumors: incidence, treatment and outcomes: a population-based study[J]. Eur J Cardiothorac Surg, 201139(4):565-569. DOI: 10.1016/j.ejcts.2010.08.036 .
返回引文位置Google Scholar
百度学术
万方数据
[4]
<x>Ts</x> <x>uta</x> K , Raso MG , Kalhor N ,et al. Histologic features of low- and intermediate-grade neuroendocrine carcinoma (typical and atypical carcinoid tumors) of the lung[J]Lung Cancer, 201171(1):34-41. DOI: 10.1016/j.lungcan.2010.04.007 .
返回引文位置Google Scholar
百度学术
万方数据
[5]
Detterbeck FC . Management of carcinoid tumors[J]. Ann Thorac Surg, 201089(3):998-1005. DOI: 10.1016/j.athoracsur.2009.07.097 .
返回引文位置Google Scholar
百度学术
万方数据
[6]
Fink G , Krelbaum T , Yellin A et al. Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from the literature[J]Chest, 2001119(6):1647-1651.
返回引文位置Google Scholar
百度学术
万方数据
[7]
Machuca TN , Cardoso PF , Camargo SM ,et al. Surgical treatment of bronchial carcinoid tumors: a single-center experience[J]Lung Cancer, 201070(2):158-162. DOI: 10.1016/j.lungcan.2010.01.015 .
返回引文位置Google Scholar
百度学术
万方数据
[8]
Buonerba C , Gallo C , Di Lorenzo G et al. Ten-year adjuvant treatment with somatostatin analogs in a patient with atypical carcinoid of the lung[J]. Anticancer Drugs, 201021(4):465-468. DOI: 10.1097/CAD.0b013e32833688a2 .
返回引文位置Google Scholar
百度学术
万方数据
[9]
Rea F , Rizzardi G , Zuin A ,et al. Outcome and surgical strategy in bronchial carcinoid tumors: single institution experience with 252 patients[J]Eur J Cardiothorac Surg, 200731(2):186-191.
返回引文位置Google Scholar
百度学术
万方数据
[10]
Schrevens L , Vansteenkiste J , Deneffe G et al. Clinical-radiological presentation and outcome of surgically treated pulmonary carcinoid tumours: a long-term single institution experience[J]Lung Cancer, 200443(1):39-45.
返回引文位置Google Scholar
百度学术
万方数据
[11]
Ferolla P , Daddi N , Urbani M ,et al. Tumorlets, multicentric carcinoids, lymph-no dal metastases, and long-term behavior in bronchial carcinoids [J]J Thorac Oncol, 20094(3):383-387. DOI: 10.1097/JTO.0b013e318197f2e7 .
返回引文位置Google Scholar
百度学术
万方数据
[12]
Martin B , Paesmans M , Mascaux C ,et al. Ki-67 expression and patients survival in lung cancer: systematic review of the literature with meta-analysis[J]Br J Cancer, 200491(12):2018-2025.
返回引文位置Google Scholar
百度学术
万方数据
备注信息
A
袁茂玲,Email: mocdef.qabq669732623
评论 (0条)
注册
登录
时间排序
暂无评论,发表第一条评论抢沙发
MedAI助手(体验版)
文档即答
智问智答
机器翻译
回答内容由人工智能生成,我社无法保证其准确性和完整性,该生成内容不代表我们的态度或观点,仅供参考。
生成快照
文献快照

你好,我可以帮助您更好的了解本文,请向我提问您关注的问题。

0/2000

《中华医学会杂志社用户协议》 | 《隐私政策》

《SparkDesk 用户协议》 | 《SparkDesk 隐私政策》

网信算备340104764864601230055号 | 网信算备340104726288401230013号

技术支持:

历史对话
本文全部
还没有聊天记录
设置
模式
纯净模式沉浸模式
字号