With the implement of long-term effective highly active antiretroviral therapy (HAART), it not only significantly improves the survival expectation of HIV-infected men, but also significantly reduces the risk of sexually transmitted infections. The combination of pre-exposure prophylaxis (PrEP) and precisely timed intercourse during easy pregnancy period significantly improves the prevention of HIV non-infected female partners from sexually transmitted infection, and has proved to be an effective way for male only HIV positive couples to conceive naturally. Using processed semen of HIV-infected men for assisted reproduction treatment, no female partner or children infection is found, which is the preferred treatment for male only HIV positive couples with decreased fertility. The quality of life and fertility desires of HIV infected people cannot be ignored.

Human immunodeficiency virus; Pre-exposure prophylaxis; Reproductive technique, assited; Natural conception; Timed intercourse; Sexually transmitted infections