Clinical Study
Study on the relationship between vitamin D level and ovarian blood flow and ovarian reserve function
Shen Huimin, Gong Pidong, Wang Chao, Wang Ruijing, Liu Yu, Wang Yaxin, Zhang Yanhui, Liu Meimei
Published 2023-08-25
Cite as Chin J Reprod Contracep, 2023, 43(8): 799-805. DOI: 10.3760/cma.j.cn101441-20220518-00217
Abstract
ObjectiveTo analyze the correlation between serum vitamin D level and ovarian artery blood flow index and ovarian reserve function in women.
MethodsA retrospective cohort study was conducted. Women aged from 18 to 40 years who were admitted to the Department of Obstetrics and Gynecology of the Second Affiliated Hospital of Harbin Medical University from September 2020 to November 2021 and had regular sexual life were selected as subjects. The data of age, height and weight were collected. And the indexes of vitamin D, anti-Müllerian hormone (AMH), luteinizing hormone and follicle-stimulating hormone were detected in the laboratory. Color Doppler ultrasound was used to measure antral follicle count and bilateral ovarian interstitial artery blood stream resistance index (RI) and plusatility index (PI) in early follicular phase. Multiple linear regression was used to analyze the related factors of serum vitamin D level.
ResultsA total of 218 women were included in the study, including 137 cases of vitamin D deficiency, accounting for 62.8%, 39 cases of vitamin D insufficiency, accounting for 17.9%, 42 cases of normal vitamin D, accounting for 19.3%. Multiple linear regression analysis showed that there was a negative correlation between serum vitamin D level and ovarian blood flow (P=0.024), but no correlation with other indexes (all P>0.05).
ConclusionSerum vitamin D level affected ovarian interstitial artery blood flow RI to some extent, but had no significant correlation with ovarian interstitial artery blood flow PI, serum AMH level and other indexes related to ovarian reserve function.
Key words:
Vitamin D; Hemodynamics; Ovarian reserve; Anti-Müllerian hormone
Contributor Information
Shen Huimin
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Gong Pidong
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Wang Chao
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Wang Ruijing
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Liu Yu
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Wang Yaxin
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Zhang Yanhui
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
Liu Meimei
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China
