Cholera vaccine is one of the main tools for prevention and control of cholera. Shanchol is a killed oral bivalent whole cell cholera vaccine, which has good immunogenicity and efficacy, and has been used in mass vaccination campaign for preventing and controlling cholera. This review summarizes related studies on the immunogenicity and application status of Shanchol vaccine, influence factors on the effect of its vaccination, and the safety of Shanchol vaccine in specific populations.

Cholera Vaccines; Vibrio cholerae; Mass Vaccination; Safety